| Literature DB >> 34737462 |
Steven Gunawan1, Nathan Bedard1, Christopher Foley1, Christopher Hulme1,2.
Abstract
This article describes the action of iodine(III) reagents [diacetoxyiodobenzene, PhI(OAc)2, and iodosobenzene, (PhIO)n] in conjunction with TMSBr which act as functional bromine equivalents in unique oxidations of saturated, carbamate protected N-heterocycles. Interestingly, during this work, treatment of the same carbamates with molecular bromine alone afforded similar products, which were sequestered by the solvent methanol.Entities:
Keywords: Bromination; CH-functionalization; Hypervalent iodine; N-Bromosuccinimide; N-acyliminium; Radical
Year: 2021 PMID： 34737462 PMCID： PMC8562708 DOI： 10.1016/j.tetlet.2021.152978
Source DB: PubMed Journal: Tetrahedron Lett ISSN： 0040-4039 Impact factor: 2.415