Literature DB >> 3464105

Threonyl-tRNA synthetase gene maps close to leucyl-tRNA synthetase gene on human chromosome 5.

S C Gerken, J J Wasmuth, S M Arfin.   

Abstract

The structural gene for threonyl-tRNA synthetase was mapped to human chromosome 5 by an analysis of the isoelectric focusing patterns of this enzyme from human X Chinese hamster interspecific somatic cell hybrids. The threonyl-tRNA synthetase gene is the fourth of seven aminoacyl-tRNA synthetase genes mapped in humans to be assigned to this chromosome. Regional mapping studies showed that the threonyl-tRNA synthetase gene is on the short arm of chromosome 5, p13-cen, and is close to, but separable from, the gene for leucyl-tRNA synthetase which maps to 5cen-5q11.

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Year:  1986        PMID: 3464105     DOI: 10.1007/BF01539923

Source DB:  PubMed          Journal:  Somat Cell Mol Genet        ISSN: 0740-7750


  3 in total

1.  Isolation of a cDNA clone for human threonyl-tRNA synthetase: amplification of the structural gene in borrelidin-resistant cell lines.

Authors:  K J Kontis; S M Arfin
Journal:  Mol Cell Biol       Date:  1989-05       Impact factor: 4.272

2.  The human QARS locus: assignment of the human gene for glutaminyl-tRNA synthetase to chromosome 1q32-42.

Authors:  N Kunze; E Bittler; R Fett; B Schray; H Hameister; K H Wiedorn; R Knippers
Journal:  Hum Genet       Date:  1990-10       Impact factor: 4.132

3.  CpG island clones from a deletion encompassing the gene for adenomatous polyposis coli.

Authors:  L Varesco; H J Thomas; S Cottrell; V Murday; S J Fennell; S Williams; S Searle; D Sheer; W F Bodmer; A M Frischauf
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205

  3 in total

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