Literature DB >> 2227938

The human QARS locus: assignment of the human gene for glutaminyl-tRNA synthetase to chromosome 1q32-42.

N Kunze1, E Bittler, R Fett, B Schray, H Hameister, K H Wiedorn, R Knippers.   

Abstract

We have used a cDNA encoding the core region of the human glutaminyl-tRNA synthetase to determine the chromosomal localization of the corresponding gene. Southern blots of restricted DNA from a panel of rodent-human cell lines and in situ chromosome hybridization gave identical results showing that the human gene locus for glutaminyl-tRNA synthetase resides on the distal long arm of chromosome 1. There are now nine mapped aminoacyl-tRNA synthetase genes in the human genome.

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Year:  1990        PMID: 2227938     DOI: 10.1007/bf00194231

Source DB:  PubMed          Journal:  Hum Genet        ISSN: 0340-6717            Impact factor:   4.132


  21 in total

1.  Assignment of a gene for tryptophanyl-transfer ribonucleic acid synthetase (E.C. 6.1.1.2) to human chromosome 14.

Authors:  R M Denney; I W Craig
Journal:  Biochem Genet       Date:  1976-02       Impact factor: 1.890

2.  New classes of common fragile sites induced by 5-azacytidine and bromodeoxyuridine.

Authors:  G R Sutherland; M I Parslow; E Baker
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

3.  Isolation of a cDNA clone for human threonyl-tRNA synthetase: amplification of the structural gene in borrelidin-resistant cell lines.

Authors:  K J Kontis; S M Arfin
Journal:  Mol Cell Biol       Date:  1989-05       Impact factor: 4.272

4.  Report of the nomenclature committee and the 1989 catalog of mapped genes.

Authors:  P J McAlpine; T B Shows; C Boucheix; L C Stranc; T G Berent; A J Pakstis; R C Douté
Journal:  Cytogenet Cell Genet       Date:  1989

Review 5.  Multienzyme complex of aminoacyl-tRNA synthetases: an essence of being eukaryotic.

Authors:  C V Dang; C V Dang
Journal:  Biochem J       Date:  1986-10-15       Impact factor: 3.857

Review 6.  Aminoacyl tRNA synthetases: general scheme of structure-function relationships in the polypeptides and recognition of transfer RNAs.

Authors:  P Schimmel
Journal:  Annu Rev Biochem       Date:  1987       Impact factor: 23.643

7.  Isolation and characterization of interspecific heat-resistant hybrids between a temperature-sensitive chinese hamster cell asparaginyl-tRNA synthetase mutant and normal human leukocytes: assignment of human asnS gene to chromosome 18.

Authors:  R E Cirullo; F X Arredondo-Vega; M Smith; J J Wasmuth
Journal:  Somatic Cell Genet       Date:  1983-03

8.  Lip pits and deletion 1q32----41.

Authors:  M Bocian; A P Walker
Journal:  Am J Med Genet       Date:  1987-02

9.  Threonyl-tRNA synthetase gene maps close to leucyl-tRNA synthetase gene on human chromosome 5.

Authors:  S C Gerken; J J Wasmuth; S M Arfin
Journal:  Somat Cell Mol Genet       Date:  1986-09

10.  Molecular cloning and primary structure of cDNA encoding the catalytic domain of rat liver aspartyl-tRNA synthetase.

Authors:  M Mirande; J P Waller
Journal:  J Biol Chem       Date:  1989-01-15       Impact factor: 5.157

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  4 in total

1.  Exons encoding the highly conserved part of human glutaminyl-tRNA synthetase.

Authors:  E Kaiser; D Eberhard; R Knippers
Journal:  J Mol Evol       Date:  1992-01       Impact factor: 2.395

2.  Human histidyl-tRNA synthetase: recognition of amino acid signature regions in class 2a aminoacyl-tRNA synthetases.

Authors:  N Raben; F Borriello; J Amin; R Horwitz; D Fraser; P Plotz
Journal:  Nucleic Acids Res       Date:  1992-03-11       Impact factor: 16.971

3.  Linkage of Van der Woude syndrome (VWS) to REN and exclusion of the candidate gene TGFB2 from the disease locus in a large pedigree.

Authors:  A Sander; H Moser; S Liechti-Gallati; T Grimm; M Zingg; J Raveh
Journal:  Hum Genet       Date:  1993-03       Impact factor: 4.132

4.  Evolution of the Glx-tRNA synthetase family: the glutaminyl enzyme as a case of horizontal gene transfer.

Authors:  V Lamour; S Quevillon; S Diriong; V C N'Guyen; M Lipinski; M Mirande
Journal:  Proc Natl Acad Sci U S A       Date:  1994-08-30       Impact factor: 11.205

  4 in total

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