Literature DB >> 3462716

Identification and transmission of hepatitis B virus-related variants.

J R Wands, Y K Fujita, K J Isselbacher, C Degott, H Schellekens, M C Dazza, V Thiers, P Tiollais, C Brechot.   

Abstract

We have identified long-incubation viral agents that share epitopes with hepatitis B virus (HBV). During chimpanzee infectivity studies, these agents may be recognized in the liver since they possess complementary nucleic acid sequences with HBV DNA; the genomic size was found to be 3.2 kilobases, identical to that of HBV. Liver injury was produced and there was antigen expression in hepatocytes. Chimpanzees were not protected by prior immunization with hepatitis B surface antigen; conversely, they were still susceptible to HBV after recovery from infection with such agents. These findings suggest that these hepatitis B virus-related variants appear to be immunologically distinct from HBV.

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Year:  1986        PMID： 3462716      PMCID： PMC386553          DOI： 10.1073/pnas.83.17.6608

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  13 in total

1.  Structural analysis of hepatitis B surface antigen by monoclonal antibodies.

Authors:  E Ben-Porath; J R Wands; R A Marciniak; M A Wong; L Hornstein; R Ryder; M Canlas; A Lingao; K J Isselbacher
Journal:  J Clin Invest       Date:  1985-10       Impact factor: 14.808

2.  High affinity monoclonal antibodies to hepatitis B surface antigen (HBsAg) produced by somatic cell hybrids.

Authors:  J R Wands; V R Zurawski
Journal:  Gastroenterology       Date:  1981-02       Impact factor: 22.682

3.  Biology of hepatitis B virus.

Authors:  P Tiollais; P Charnay; G N Vyas
Journal:  Science       Date:  1981-07-24       Impact factor: 47.728

4.  Monoclonal IgM radioimmunoassay for hepatitis B surface antigen: high binding activity in serum that is unreactive with conventional antibodies.

Authors:  J R Wands; R R Bruns; R I Carlson; A Ware; J E Menitove; K J Isselbacher
Journal:  Proc Natl Acad Sci U S A       Date:  1982-02       Impact factor: 11.205

5.  Detection of hepatitis B virus DNA in serum by a simple spot hybridization technique: comparison with results for other viral markers.

Authors:  J Scotto; M Hadchouel; C Hery; J Yvart; P Tiollais; C Brechot
Journal:  Hepatology       Date:  1983 May-Jun       Impact factor: 17.425

6.  Immunodiagnosis of hepatitis B with high-affinity IgM monoclonal antibodies.

Authors:  J R Wands; R I Carlson; H Schoemaker; K J Isselbacher; V R Zurawski
Journal:  Proc Natl Acad Sci U S A       Date:  1981-02       Impact factor: 11.205

7.  Presence of integrated hepatitis B virus DNA sequences in cellular DNA of human hepatocellular carcinoma.

Authors:  C Brechot; C Pourcel; A Louise; B Rain; P Tiollais
Journal:  Nature       Date:  1980-07-31       Impact factor: 49.962

8.  Hepatitis B viral antigenic structure: signature analysis by monoclonal radioimmunoassays.

Authors:  J R Wands; M A Wong; J Shorey; R D Brown; R A Marciniak; K J Isselbacher
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205

9.  Demonstration of previously undetected hepatitis B viral determinants in an Australian Aboriginal population by monoclonal anti-hbs antibody radioimmunoassays.

Authors:  J R Wands; R A Marciniak; K J Isselbacher; M Varghese; G Don; J W Halliday; L W Powell
Journal:  Lancet       Date:  1982-05-01       Impact factor: 79.321

10.  Hepatitis B virus antigens made in microbial cells immunise against viral infection.

Authors:  K Murray; S A Bruce; A Hinnen; P Wingfield; P M van Erd; A de Reus; H Schellekens
Journal:  EMBO J       Date:  1984-03       Impact factor: 11.598
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  10 in total

1.  Effects of interferon-alpha therapy on serum and liver HBV DNA in patients with chronic hepatitis B.

Authors:  S V Feinman; B Berris; R Sooknanan; B Fernandes; S Bojarski
Journal:  Dig Dis Sci       Date:  1992-10       Impact factor: 3.199

2.  Hepatitis B virus "escape" mutants.

Authors:  D H Crawford
Journal:  BMJ       Date:  1990-11-10

3.  Prevalence of HBeAg, anti-HBe serological markers and HBV-DNA in asymptomatic carriers in Ethiopia.

Authors:  M Rapicetta; K Hailù; G Morace; L Bisanti; A M Di Rienzo; A R Ciccaglione; D Bekura; P Pasquini; G B Rossi
Journal:  Eur J Epidemiol       Date:  1989-12       Impact factor: 8.082

4.  Global control of hepatitis B virus: does treatment-induced antigenic change affect immunization?

Authors:  C John Clements; Ben Coghlan; Mick Creati; Stephen Locarnini; Richard S Tedder; Joseph Torresi
Journal:  Bull World Health Organ       Date:  2009-10-23       Impact factor: 9.408

5.  Risk of hepatitis B infections in Olympic wrestling.

Authors:  S Bereket-Yücel
Journal:  Br J Sports Med       Date:  2007-03-01       Impact factor: 13.800

Review 6.  The detection of hepatitis B virus (HBV) in HBsAG negative individuals with primary liver cancer.

Authors:  P Paterlini; C Bréchot
Journal:  Dig Dis Sci       Date:  1991-08       Impact factor: 3.199

7.  Sensitivity of seven commercial assays in the detection of hepatitis B virus type 2-like infection.

Authors:  P León; J A López; J M Echevarría
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1992-07       Impact factor: 3.267

8.  Hepatitis C virus associated primary hepatocellular carcinoma in a noncirrhotic liver.

Authors:  W Herr; G Gerken; T Poralla; S Immenschuh; P Schirmacher; K W Steegmüller; H Schwickert; K H Meyer zum Büschenfelde
Journal:  Clin Investig       Date:  1993-01

9.  Anti-HBc screening for the prevention of perinatal transmission of hepatitis B virus in France.

Authors:  B Descos; J Scotto; V Fayol; J Y Huet; C Pichoud; M Hermier; G Ville; F Charvet; D Dargent; J M Thoulon
Journal:  Infection       Date:  1987 Nov-Dec       Impact factor: 3.553

10.  Rapid identification of low level hepatitis B-related viral genome in serum.

Authors:  T J Liang; K J Isselbacher; J R Wands
Journal:  J Clin Invest       Date:  1989-10       Impact factor: 14.808
  10 in total

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