Literature DB >> 34609310

Analysis of Quality of Life, Depression, and Sexual Function in Patients on the Liver Transplant List.

Cihan Fidan1, Aydıncan Akdur2, Mahir Kırnap2, Haldun Selçuk3, Sedat Yıldırım2, Gökhan Moray2, Mehmet Haberal2.   

Abstract

BACKGROUND: The only treatment in patients developing liver failure is liver transplantation. According to the Ministry of Health, the number of patients waiting for a liver transplantation is 2141, the average waiting period for liver transplantation is approximately 5 years, and 15-18% of these patients lose their life while waiting for transplantation. In these patients, limitations in daily activities and depression-anxiety are commonly found. The aim of this study was to analyze life quality, depression symptoms, and existence of sexual functional disorders of patients waiting for liver transplantation.
METHODS: A total of 74 patients, who were registered in Başkent University Hospital between 2015 and 2018, were included into the study. Short Form-36, Beck Depression Inventory, and Arizona Sexual Experiences Scale were applied to 56 patients who approved study.
RESULTS: Most of the patients were male (64.3%), and the mean age was 46 (18-64). Short Form-36 scores were low in all patients. The mean Beck Depression Inventory score of patients was found as 18.4 ± 11.3, and they were suffering from moderate depressive symptoms. According to Arizona Sexual Experiences Scale, total mean scores of males was found as 16.3 ± 5.5, and for females, it was 19.5 ± 5.3 with a statistically significant difference (P < .05). It was found that sexual dysfunction mostly had moderate to mild.
CONCLUSION: Depression and sexual dysfunction are common in patients with chronic liver diseases, and their life qualities deteriorate significantly. It is anticipated that evaluation of these patients in terms of psychological issues and sexual dysfunction will increase their quality of life during the organ waiting period and affect their well-being post-transplant.

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Year:  2021        PMID: 34609310      PMCID: PMC8975440          DOI: 10.5152/tjg.2021.21229

Source DB:  PubMed          Journal:  Turk J Gastroenterol        ISSN: 1300-4948            Impact factor:   1.555


  26 in total

1.  The Arizona Sexual Experience Scale (ASEX): reliability and validity.

Authors:  C A McGahuey; A J Gelenberg; C A Laukes; F A Moreno; P L Delgado; K M McKnight; R Manber
Journal:  J Sex Marital Ther       Date:  2000 Jan-Mar

2.  Waiting for a liver transplant: psychosocial well-being, spirituality, and need for counselling.

Authors:  L Goetzmann; R Wagner-Huber; R Klaghofer; B Muellhaupt; P A Clavien; C Buddeberg; E Scheuer
Journal:  Transplant Proc       Date:  2006-11       Impact factor: 1.066

3.  Quality of Life and Group Psychological Intervention in Patients With Cirrhosis on Liver Transplant Waiting List.

Authors:  B Febrero; P Ramírez; L Martínez-Alarcón; C Abete; M Galera; A Ríos; R Robles-Martínez; P M Ramírez-Pino; J Almela; G Ramis; J A Pons; P Parrilla
Journal:  Transplant Proc       Date:  2018-04-11       Impact factor: 1.066

4.  The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection.

Authors:  J E Ware; C D Sherbourne
Journal:  Med Care       Date:  1992-06       Impact factor: 2.983

5.  Health-related quality of life and affective status in liver transplant recipients and patients on the waiting list with low MELD scores.

Authors:  Christian Benzing; Nicco Krezdorn; Julia Förster; Andreas Hinz; Felix Krenzien; Georgi Atanasov; Moritz Schmelzle; Hans-Michael Hau; Michael Bartels
Journal:  HPB (Oxford)       Date:  2016-04-20       Impact factor: 3.647

6.  Health-related quality of life and psychological correlates in patients listed for liver transplantation.

Authors:  Jolie J Gutteling; Robert A de Man; Jan J V Busschbach; Anne-Sophie E Darlington
Journal:  Hepatol Int       Date:  2007-11-21       Impact factor: 6.047

Review 7.  Sexual dysfunction in chronic liver disease: is liver transplantation an effective cure?

Authors:  Patrizia Burra; Giacomo Germani; Annalisa Masier; Eleonora De Martin; Martina Gambato; Andrea Salonia; Patrizio Bo; Alessandro Vitale; Umberto Cillo; Francesco Paolo Russo; Marco Senzolo
Journal:  Transplantation       Date:  2010-06-27       Impact factor: 4.939

Review 8.  Depression and Anxiety as Risk Factors for Morbidity and Mortality After Organ Transplantation: A Systematic Review and Meta-Analysis.

Authors:  Mary Amanda Dew; Emily M Rosenberger; Larissa Myaskovsky; Andrea F DiMartini; Annette J DeVito Dabbs; Donna M Posluszny; Jennifer Steel; Galen E Switzer; Diana A Shellmer; Joel B Greenhouse
Journal:  Transplantation       Date:  2015-05       Impact factor: 4.939

Review 9.  Quality of life after liver transplantation: State of the art.

Authors:  Louis Onghena; Wouter Develtere; Carine Poppe; Anja Geerts; Roberto Troisi; Aude Vanlander; Frederik Berrevoet; Xavier Rogiers; Hans Van Vlierberghe; Xavier Verhelst
Journal:  World J Hepatol       Date:  2016-06-28

10.  Quality of life after adult living donor liver transplantation: A longitudinal prospective follow-up study.

Authors:  Junichi Togashi; Yasuhiko Sugawara; Nobuhisa Akamatsu; Sumihito Tamura; Noriyo Yamashiki; Junichi Kaneko; Yoshihiro Sakamoto; Taku Aoki; Kiyoshi Hasegawa; Norihiro Kokudo
Journal:  Hepatol Res       Date:  2013-02-01       Impact factor: 4.288

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