Literature DB >> 34595743

Chemical Probes for Histamine Receptor Subtypes.

Markus Falkenstein1, Milica Elek1, Holger Stark2.   

Abstract

Ligands with different properties and different selectivity are highly needed for in vitro and in vivo studies on the (patho)physiological influence of the chemical mediator histamine and its receptor subtypes. A selection of well-described ligands for the different receptor subtypes and different studies is shown with a particular focus on affinity and selectivity. In addition, compounds with radioactive or fluorescence elements will be presented with their beneficial use for other species or different investigations.
© 2021. The Author(s), under exclusive license to Springer Nature Switzerland AG.

Entities:  

Keywords:  Fluorescence; Histamine; Histamine H1 receptor; Histamine H2 receptor; Histamine H3 receptor; Histamine H4 receptor; PET; Radioligands

Mesh：

Substances：

Year:  2022        PMID： 34595743     DOI： 10.1007/7854_2021_254

Source DB:  PubMed          Journal:  Curr Top Behav Neurosci        ISSN： 1866-3370


  183 in total

1.  Visual detection of transport-P in peptidergic neurones.

Authors:  S al-Damluji; D Porter; L Z Krsmanovic; J R Knutson; I J Kopin
Journal:  Br J Pharmacol       Date:  1997-03       Impact factor: 8.739

2.  Evaluation of 11C-GSK189254 as a novel radioligand for the H3 receptor in humans using PET.

Authors:  Sharon Ashworth; Eugenii A Rabiner; Roger N Gunn; Christophe Plisson; Alan A Wilson; Robert A Comley; Robert Y K Lai; Antony D Gee; Marc Laruelle; Vincent J Cunningham
Journal:  J Nucl Med       Date:  2010-06-16       Impact factor: 10.057

3.  Structure-activity studies on a series of a 2-aminopyrimidine-containing histamine H4 receptor ligands.

Authors:  Robert J Altenbach; Ronald M Adair; Brian M Bettencourt; Lawrence A Black; Shannon R Fix-Stenzel; Sujatha M Gopalakrishnan; Gin C Hsieh; Huaqing Liu; Kennan C Marsh; Michael J McPherson; Ivan Milicic; Thomas R Miller; Timothy A Vortherms; Usha Warrior; Jill M Wetter; Neil Wishart; David G Witte; Prisca Honore; Timothy A Esbenshade; Arthur A Hancock; Jorge D Brioni; Marlon D Cowart
Journal:  J Med Chem       Date:  2008-09-24       Impact factor: 7.446

4.  Differential effects of functionally different histamine H4 receptor ligands on acute irritant dermatitis in mice.

Authors:  Maristella Adami; Cristina Micheloni; Daniela Grandi; Holger Stark
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2018-08-25       Impact factor: 3.000

Review 5.  Histamine in the immune regulation of allergic inflammation.

Authors:  Cezmi A Akdis; Kurt Blaser
Journal:  J Allergy Clin Immunol       Date:  2003-07       Impact factor: 10.793

6.  Constitutive activity and structural instability of the wild-type human H2 receptor.

Authors:  A E Alewijnse; M J Smit; M Hoffmann; D Verzijl; H Timmerman; R Leurs
Journal:  J Neurochem       Date:  1998-08       Impact factor: 5.372

7.  Acute wake-promoting actions of JNJ-5207852, a novel, diamine-based H3 antagonist.

Authors:  A J Barbier; C Berridge; C Dugovic; A D Laposky; S J Wilson; J Boggs; L Aluisio; B Lord; C Mazur; C M Pudiak; X Langlois; W Xiao; R Apodaca; N I Carruthers; T W Lovenberg
Journal:  Br J Pharmacol       Date:  2004-10-04       Impact factor: 8.739

8.  A novel series of histamine H4 receptor antagonists based on the pyrido[3,2-d]pyrimidine scaffold: comparison of hERG binding and target residence time with PF-3893787.

Authors:  Mounir Andaloussi; Herman D Lim; Tiffany van der Meer; Maarten Sijm; Chris B M Poulie; Iwan J P de Esch; Rob Leurs; Rogier A Smits
Journal:  Bioorg Med Chem Lett       Date:  2013-03-01       Impact factor: 2.823

9.  Famotidine, an Antiulcer Agent, Strongly Inhibits Helicobacter pylori and Human Carbonic Anhydrases.

Authors:  Andrea Angeli; Marta Ferraroni; Claudiu T Supuran
Journal:  ACS Med Chem Lett       Date:  2018-09-04       Impact factor: 4.345

10.  The promise and peril of chemical probes.

Authors:  Cheryl H Arrowsmith; James E Audia; Christopher Austin; Jonathan Baell; Jonathan Bennett; Julian Blagg; Chas Bountra; Paul E Brennan; Peter J Brown; Mark E Bunnage; Carolyn Buser-Doepner; Robert M Campbell; Adrian J Carter; Philip Cohen; Robert A Copeland; Ben Cravatt; Jayme L Dahlin; Dashyant Dhanak; Aled M Edwards; Mathias Frederiksen; Stephen V Frye; Nathanael Gray; Charles E Grimshaw; David Hepworth; Trevor Howe; Kilian V M Huber; Jian Jin; Stefan Knapp; Joanne D Kotz; Ryan G Kruger; Derek Lowe; Mary M Mader; Brian Marsden; Anke Mueller-Fahrnow; Susanne Müller; Ronan C O'Hagan; John P Overington; Dafydd R Owen; Saul H Rosenberg; Bryan Roth; Brian Roth; Ruth Ross; Matthieu Schapira; Stuart L Schreiber; Brian Shoichet; Michael Sundström; Giulio Superti-Furga; Jack Taunton; Leticia Toledo-Sherman; Chris Walpole; Michael A Walters; Timothy M Willson; Paul Workman; Robert N Young; William J Zuercher
Journal:  Nat Chem Biol       Date:  2015-08       Impact factor: 15.040
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