| Literature DB >> 34546894 |
Candice D Donaldson1,2, Theodore W Heyming3, Louis Ehwerhemuepha3,4, Brooke N Jenkins1,2,4, Michelle A Fortier2,3,5, William Feaster3, Zeev N Kain2,3,4,6.
Abstract
INTRODUCTION: Children and adolescents are not impervious to the unprecedented epidemic of opioid misuse in the United States. In 2016 more than 88,000 adolescents between the ages of 12-17 reported misusing opioid medication, and evidence suggests that there has been a rise in opioid-related mortality for pediatric patients. A major source of prescribed opioids for the treatment of pain is the emergency department (ED). The current study sought to assess the complex relationship between opioid administration, pain severity, and parent satisfaction with children's care in a pediatric ED.Entities:
Mesh:
Substances:
Year: 2021 PMID: 34546894 PMCID: PMC8463050 DOI: 10.5811/westjem.2021.6.51054
Source DB: PubMed Journal: West J Emerg Med ISSN: 1936-900X
Pediatric patient sample characteristics (N = 15,895).
| Demographic and Clincal Predictors | |
|---|---|
| Age | |
| Range | 0 – 17 years |
| M (SD) | 6.69 (5.19) |
| Ethnicity | |
| Hispanic | 5,786 (63.60%) |
| Non-Hispanic | 10,109 (36.40%) |
| Sex | |
| Male | 8,494 (53.44%) |
| Female | 7,401 (46.56%) |
| Low-income insurance (medicare/medi-cal) | |
| No | 4,419 (27.80%) |
| Yes | 11,476 (72.20%) |
| Acuity Score | |
| 1/2 (Resuscitation/Emergent) | 1,192 (7.50%) |
| 3 (Urgent) | 5,516 (34.70%) |
| 4/5 (Less Urgent/Non-Urgent) | 9,187 (57.80%) |
| Length of stay (minutes) | |
| Range | 16 – 716 |
| M (SD) | 170.00 (94.85) |
| Pain severity | |
| Range | 0 – 10 |
| M (SD) | 1.86 (2.72) |
| Administered opioids | |
| No | 15,109 (95.06%) |
| Yes | 786 (4.94%) |
| Administered non-opioids | |
| No | 7,683 (48.30%) |
| Yes | 8,212 (51.70%) |
|
| |
| Top International Classification of Diseases, Ninth/Tenth Revision Diagnoses | |
|
| |
| Bacterial/viral infections (A00–A99) | 1,149 (7.23%) |
| Circulatory system diseases (I00–I99) | 159 (1.00%) |
| Congenital malformations, deformations and chromosomal abnormalities (Q00–Q99) | 219 (1.38%) |
| Digestive and genitourinary system diseases (K00–K95, N00–N99) | 1,764 (11.10%) |
| Ear and eye diseases (H00–H59, H60–H95) | 1,351 (8.50%) |
| Endocrine, nutritional, and metabolic diseases (E00–E89) | 253 (1.59%) |
| Mental and behavioral disorders (F01–F99) | 556 (3.50%) |
| Diseases of the skin and subcutaneous tissue, musculoskeletal system, and connective tissue (L00–L99, M00–M99) | 2,050 (12.90%) |
| Diseases of the nervous system (G00–G99) | 283 (1.78%) |
| Diseases of the respiratory system (J00–J99) | 2,956 (18.60%) |
| Single body region traumatic injuries non-orthopedic (S00–S391) | 1,717 (10.80%) |
| Orthopedic injury (S40–S991) | 2,273 (14.30%) |
| Unspecified body regions, poisonings, other consequences of external causes, and all other trauma or injury (T00–T141, T15–T791) | 741 (4.66%) |
Note. Only top medical diagnoses that captured >/= 1% of patients were assessed. M, Mean; SD, standard deviation.
Results of bivariate analysis.
| Variables | Levels | Not Satisfied | Satisfied | Odds Ratio (95% CI) | Chi-square P-value |
|---|---|---|---|---|---|
| Acuity Score | 1/2 (Resuscitation/Emergent) | 247 (20.83) | 939 (79.17) | Reference | 0.002 |
| 3 (Urgent) | 1327 (24.07) | 4187 (75.93) | 0.83 (0.711, 0.966) | ||
| 4/5 (Less Urgent/Non-Urgent) | 2326 (25.30) | 6869 (74.70) | 0.777 (0.669, 0.899) | ||
| Pain severity | - | 1.73 (2.61) | 1.91 (2.75) | 1.026 (1.012, 1.04) | < 0.001 |
| Administered opioids | No | 3735 (24.72) | 11374 (75.28) | Reference | 0.018 |
| Yes | 165 (20.99) | 621 (79.01) | 1.236 (1.04, 1.477) | ||
| Administered non-opioids | No | 1926 (25.07) | 5757 (74.93) | Reference | 0.131 |
| Yes | 1974 (24.04) | 6238 (75.96) | 1.057 (0.983, 1.136) | ||
| Did the staff do everything they could to help your child with his/her discomfort? | Yes, definitely | 1274 (32.67) | 9187 (76.59) | Reference | < 0.001 |
| Yes, mostly | 1023 (26.23) | 1768 (14.74) | 0.240 (0.218, 0.264) | ||
| Yes, somewhat | 845 (21.67) | 730 (6.09) | 0.120 (0.107, 0.134) | ||
| No | 710 (18.21) | 146 (1.22) | 0.029 (0.024, 0.034) | ||
| Not applicable | 48 (1.23) | 164 (1.37) | 0.474 (0.345, 0.664) | ||
| Did the care providers do everything they could to ease your child’s discomfort? | Yes, definitely | 737 (18.90) | 5755 (47.98) | Reference | < 0.001 |
| Yes, mostly | 607 (15.56) | 1199 (10.00) | 0.253 (0.223, 0.286) | ||
| Yes, somewhat | 516 (13.23) | 458 (3.82) | 0.114 (0.098, 0.132) | ||
| No | 455 (11.67) | 94 (0.78) | 0.026 (0.021, 0.033) | ||
| Not applicable | 1585 (40.64) | 4489 (37.42) | 0.363 (0.329, 0.399) |
Note.
denotes statistical significance at the p < 0.050 level.
Results of multivariate analyses.
| Main Effects | Odds Ratio (95% CI) | P-value |
|---|---|---|
| Age | 1.034 (1.022, 1.046) | < 0.001 |
| --- | 1.034 (1.022, 1.046) | < 0.001 |
| Ethnicity | ||
| Hispanic | Reference | |
| Non-Hispanic | 0.644 (0.587, 0.706) | < 0.001 |
| Sex | ||
| Female | Reference | |
| Male | 0.9715 (0.892, 1.058) | 0.507 |
| Low-income insurance (medicare/medi-cal) | ||
| No | Reference | |
| Yes | 1.834 (1.660, 2.0260) | < 0.001 |
| Acuity Score | ||
| 1/2 (Resuscitation/Emergent) | Reference | |
| 3 (Urgent) | 0.545 (0.450, 0.658) | 0.060 |
| 4/5 (Less Urgent/Non-Urgent) | 0.545 (0.450, 0.658) | < 0.001 |
| Length of stay | ||
| --- | 0.996 (0.996, 0.997) | < 0.001 |
| Pain severity | ||
| --- | 1.034 (0.993, 1.076) | 0.105 |
| Administered opioids | ||
| No | Reference | |
| Yes | 3.537 (1.458, 9.089) | 0.007 |
| Administered non-opioids | ||
| No | Reference | |
| Yes | 1.053 (0.963, 1.1535) | 0.256 |
| Did the staff do everything they could to help your child with his/her discomfort? | ||
| Yes, definitely | Reference | |
| Yes, mostly | 0.304 (0.272, 0.340) | < 0.001 |
| Yes, somewhat | 0.177 (0.154, 0.203) | < 0.001 |
| No | 0.058 (0.047, 0.071) | < 0.001 |
| Not applicable | 0.614 (0.440, 0.872) | 0.005 |
| Did the care providers do everything they could to ease your child’s discomfort? | ||
| Yes, definitely | Reference | |
| Yes, mostly | 0.515 (0.446, 0.596) | < 0.001 |
| Yes, somewhat | 0.371 (0.310, 0.444) | < 0.001 |
| No | 0.157 (0.120, 0.209) | < 0.001 |
| Not applicable | 0.622 (0.559, 0.692) | < 0.001 |
|
| ||
| Interaction Effects | Odds Ratio (95% CI) | P-value |
|
| ||
| Age × opioid administration | 0.869 (0.796, 0.947) | 0.001 |
| Age × pain severity | 0.996 (0.992, 0.999) | 0.023 |
| Opioid administration × pain severity | 0.859 (0.718, 1.0257) | 0.095 |
| Age × pain severity × opioid administration | 1.022 (1.006, 1.038) | 0.007 |
Note. ICD 9/10 diagnoses were controlled for in the multivariate model but are not depicted in this table to maintain conceptual clarity.
denotes statistical significance at the p < 0.025 level.
Figure 1Three-way interaction of age, pain severity, and opioid administration on parent likelihood to provide a positive facility rating controlling for all other demographic, clinical, and top diagnosis covariates. Age by pain severity interactions were graphed for patients were not given an opioid (left) and for those that were administered an opioid (right).