| Literature DB >> 345441 |
A M Lefer, M L Ogletree, J B Smith, M J Silver, K C Nicolaou, W E Barnette, G P Gasic.
Abstract
Prostacyclin, a potent, naturally occurring prostaglandin exerts a variety of cardiovascular and cellular actions of potential value in acute myocardial ischemia. These properties include the reduction of systemic blood pressure without changing heart rate, the lowering of coronary vascular and total peripheral resistance, the inhibition of platelet aggregation and the concomitant formation of thromboxane B2, and the reduction of the release of lysosomal enzymes.Entities:
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Year: 1978 PMID： 345441 DOI： 10.1126/science.345441
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728