Literature DB >> 34405319

In Silico Hemodynamics and Filtering Evaluation of a Commercial Embolic Protection Device.

Antonio Gil1, Pedro Quintero2, Andrea Mares1, Juan Ribera de Serra3, Manuel Ignacio Sánchez-Nevárez4, Manuel Miralles4.   

Abstract

During the last years, several kinds of Embolic Protection Devices (EPD) have been developed, with the aim of minimizing complication caused by thrombi generated during Carotid Artery Stenting (CAS). These devices are capable of capturing small particles generated during the intervention, avoiding cerebral stroke and improving the outcomes of the surgery. However, they have associated complications, like the increase on flow resistance associated by their use or the lack of knowledge on their actual filtration efficiency for thrombi of low size. Current work proposes a validated computational methodology in order to predict the hemodynamic features and filtering efficiency of a commercial EPD. It will be observed how Computational Fluid Dynamics predicts pressure drop with fair agreement with the experimental measurements. Finally, this work analyzes the filtration efficiency and the influence of the distribution of injected particles on this parameter. The capabilities of the filter for retaining particles of diameter below the pore size is, additionally, discussed.
© 2021. Biomedical Engineering Society.

Entities:  

Keywords:  Computational fluid dynamics; Discrete element method; Embolic protection device; Filtration efficiency; Hemodynamics

Mesh:

Year:  2021        PMID: 34405319     DOI: 10.1007/s10439-021-02846-4

Source DB:  PubMed          Journal:  Ann Biomed Eng        ISSN: 0090-6964            Impact factor:   3.934


  3 in total

1.  Computational modeling of distal protection filters.

Authors:  Gail M Siewiorek; Ender A Finol
Journal:  J Endovasc Ther       Date:  2010-12       Impact factor: 3.487

2.  Correlation of periprocedural systolic blood pressure changes with neurological events in high-risk carotid stent patients.

Authors:  Marcus Howell; Zvonimir Krajcer; Kathy Dougherty; Neil Strickman; Mark Skolkin; Barry Toombs; David Paniagua
Journal:  J Endovasc Ther       Date:  2002-12       Impact factor: 3.487

3.  The Effect of Geometric and Hemodynamic Parameters on Blood Flow Efficiency in Repaired Tetralogy of Fallot Patients.

Authors:  Leslie Louvelle; Matthew Doyle; Glen Van Arsdell; Cristina Amon
Journal:  Ann Biomed Eng       Date:  2021-04-09       Impact factor: 3.934

  3 in total

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