Kuntay Kaplan1, Emre Turgut2,2, Gokalp Okut1, Yusuf Murat Bag3, Fatih Sumer4, Cuneyt Kayaalp5. 1. Department of Gastrointestinal Surgery, Inonu University, Malatya, Turkey. 2. Department of Gastrointestinal Surgery, Inonu University, Malatya, Turkey. dr.emrtrgt@gmail.com. 3. Department of Gastrointestinal Surgery, Health Sciences University Van Training and Research Hospital, Van, Turkey. 4. Department of Gastrointestinal Surgery, Irmet Hospital International, Çerkezköy, Turkey. 5. Department of Gastrointestinal Surgery, Yeditepe University, Istanbul, Turkey.
Abstract
BACKGROUND: The relationship between high body mass index (BMI) and Helicobacter pylori (HP) was reported previously. But the mechanism is not clear. We aimed to evaluate the effect of HP on gastric compliance and volumes in obese patients. MATERIALS AND METHODS: One hundred fifty-nine patients who underwent sleeve gastrectomy due to morbid obesity were enrolled in the study and were divided into two groups as HP+ (n = 86) and HP- (n = 73) according to the HP status in resection materials. Demographics, pathological data, specimen sizes, volume, and compliance were retrospectively analyzed. RESULTS: The median age of the study group was 34 years (17-64 years) while the median BMI was 43 kg/m2 (35-64, 3 kg/m2). Most of the patients (n = 134, 84.3%) were female. The median diameter of the widest point of the specimen was 22.5 cm (14-32 cm), and the median volume of the specimen was 790 cc (330-1920 cc). Both the diameter of the widest point and the volume of the specimens were significantly increased in the HP+ group compared to the HP- group (p < 0.001 and p = 0.017, respectively). In addition, the median compliance was 52.6 cc/mmHg, and the compliance was significantly higher (p < 0.001) in the HP+ group. There were no significant differences in specimen sizes between the two groups. CONCLUSION: This is the first study showing that HP increases gastric compliance in obese patients who underwent LSG. The etiology and the effects of this increase in compliance have not been fully clarified yet. Further studies are needed to shed light on these effects.
BACKGROUND: The relationship between high body mass index (BMI) and Helicobacter pylori (HP) was reported previously. But the mechanism is not clear. We aimed to evaluate the effect of HP on gastric compliance and volumes in obesepatients. MATERIALS AND METHODS: One hundred fifty-nine patients who underwent sleeve gastrectomy due to morbid obesity were enrolled in the study and were divided into two groups as HP+ (n = 86) and HP- (n = 73) according to the HP status in resection materials. Demographics, pathological data, specimen sizes, volume, and compliance were retrospectively analyzed. RESULTS: The median age of the study group was 34 years (17-64 years) while the median BMI was 43 kg/m2 (35-64, 3 kg/m2). Most of the patients (n = 134, 84.3%) were female. The median diameter of the widest point of the specimen was 22.5 cm (14-32 cm), and the median volume of the specimen was 790 cc (330-1920 cc). Both the diameter of the widest point and the volume of the specimens were significantly increased in the HP+ group compared to the HP- group (p < 0.001 and p = 0.017, respectively). In addition, the median compliance was 52.6 cc/mmHg, and the compliance was significantly higher (p < 0.001) in the HP+ group. There were no significant differences in specimen sizes between the two groups. CONCLUSION: This is the first study showing that HP increases gastric compliance in obesepatients who underwent LSG. The etiology and the effects of this increase in compliance have not been fully clarified yet. Further studies are needed to shed light on these effects.
Authors: Richard Welbourn; Marianne Hollyman; Robin Kinsman; John Dixon; Ronald Liem; Johan Ottosson; Almino Ramos; Villy Våge; Salman Al-Sabah; Wendy Brown; Ricardo Cohen; Peter Walton; Jacques Himpens Journal: Obes Surg Date: 2018-11-12 Impact factor: 4.129
Authors: K S Ahmed; A A Khan; I Ahmed; S K Tiwari; M A Habeeb; S M Ali; J D Ahi; Z Abid; A Alvi; M A Hussain; N Ahmed; C M Habibullah Journal: Singapore Med J Date: 2006-04 Impact factor: 1.858
Authors: F Mearin; X de Ribot; A Balboa; A Salas; M J Varas; M Cucala; R Bartolomé; J R Armengol; J R Malagelada Journal: Gut Date: 1995-07 Impact factor: 23.059
Authors: Jatin Roper; Fritz Francois; Peter L Shue; Michelle S Mourad; Zhiheng Pei; Asalia Z Olivares de Perez; Guillermo I Perez-Perez; Chi-Hong Tseng; Martin J Blaser Journal: J Clin Endocrinol Metab Date: 2008-04-08 Impact factor: 5.958
Authors: Antonietta Gerarda Gravina; Rocco Maurizio Zagari; Cristiana De Musis; Lorenzo Romano; Carmelina Loguercio; Marco Romano Journal: World J Gastroenterol Date: 2018-08-07 Impact factor: 5.742