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Literature DB >> 3430552

Trisomy 13 ascertained in a survey of spontaneous abortions.

P A Jacobs¹, T J Hassold, A Henry, D Pettay, N Takaesu.

Abstract

In a series of 2922 karyotyped spontaneous abortions, 62 were found to be trisomic for chromosome 13, 46 having a simple trisomy and 16 a translocation trisomy. The epidemiology of this series of trisomy 13 conceptuses is presented and compared to that of trisomy 13 ascertained from other populations. In most compared parameters the trisomy 13 spontaneous abortions are very similar. However, there is no evidence in our material for the fall in proportion of trisomy 13 conceptuses at very advanced maternal ages that has been reported in three previous studies, one of spontaneous abortions and two of amniocentesis specimens.

Entities: Disease

Mesh：

Year: 1987 PMID： 3430552 PMCID： PMC1050400 DOI： 10.1136/jmg.24.12.721

Source DB: PubMed Journal: J Med Genet ISSN： 0022-2593 Impact factor: 6.318

11 in total

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Authors: N Risch; Z Stein; J Kline; D Warburton
Journal: Am J Hum Genet Date: 1986-07 Impact factor: 11.025

2. Parental age and unbalanced Robertsonian translocations associated with Down syndrome and Patau syndrome: comparison with maternal and paternal age effects for 47, +21 and 47, +13.

Authors: E B Hook
Journal: Ann Hum Genet Date: 1984-10 Impact factor: 1.670

3. Maternal age specific rates for chromosome aberrations and factors influencing them: report of a collaborative european study on 52 965 amniocenteses.

Authors: M A Ferguson-Smith; J R Yates
Journal: Prenat Diagn Date: 1984 Impact factor: 3.050

4. The frequency of 47,+21,47,+18, and 47,+13 at the uppermost extremes of maternal ages: results on 56,094 fetuses studied prenatally and comparisons with data on livebirths.

Authors: E B Hook; P K Cross; R R Regal
Journal: Hum Genet Date: 1984 Impact factor: 4.132

5. Parental origin of de novo chromosome rearrangements.

Authors: J Chamberlin; R E Magenis
Journal: Hum Genet Date: 1980 Impact factor: 4.132

6. A cytogenetic study of 1000 spontaneous abortions.

Authors: T Hassold; N Chen; J Funkhouser; T Jooss; B Manuel; J Matsuura; A Matsuyama; C Wilson; J A Yamane; P A Jacobs
Journal: Ann Hum Genet Date: 1980-10 Impact factor: 1.670

7. A cytogenetic study of spontaneous abortions in Hawaii.

Authors: T J Hassold; A Matsuyama; I M Newlands; J S Matsuura; P A Jacobs; B Manuel; J Tsuei
Journal: Ann Hum Genet Date: 1978-05 Impact factor: 1.670

8. The effect of structural aberrations of the chromosomes on reproductive fitness in man. II. Results.

Authors: P A Jacobs; A Frackiewicz; P Law; C J Hilditch; N E Morton
Journal: Clin Genet Date: 1975-09 Impact factor: 4.438

9. Maternal age-specific rates of numerical chromosome abnormalities with special reference to trisomy.

Authors: T Hassold; D Chiu
Journal: Hum Genet Date: 1985 Impact factor: 4.132

10. Unbalanced Robertsonian translocations associated with Down's syndrome or Patau's syndrome: chromosome subtype, proportion inherited, mutation rates, and sex ratio.

Authors: E B Hook
Journal: Hum Genet Date: 1981 Impact factor: 4.132

6 in total

1. Use of cross-species in-situ hybridization (ZOO-FISH) to assess chromosome abnormalities in day-6 in-vivo- or in-vitro-produced sheep embryos.

Authors: Gianfranco Coppola; Basil Alexander; Dino Di Berardino; Elizabeth St John; Parvathi K Basrur; W Allan King
Journal: Chromosome Res Date: 2007-05-10 Impact factor: 5.239