| Literature DB >> 34288070 |
Myrte Westerneng1, Ank de Jonge1, Anneloes L van Baar2, Anke B Witteveen1, Petra Jellema1, K Marieke Paarlberg3, Marlies Rijnders4, Henriëtte E van der Horst5.
Abstract
BACKGROUND: Third-trimester routine ultrasounds are increasingly offered to monitor fetal growth. In addition to limited evidence for its clinical effectiveness, little is known about its importance for pregnancy-specific anxiety and mother-to-infant bonding.Entities:
Keywords: cluster-randomized trial; maternal bonding; pregnancy anxiety; third-trimester routine ultrasound
Mesh:
Year: 2021 PMID: 34288070 PMCID: PMC9290476 DOI: 10.1111/birt.12573
Source DB: PubMed Journal: Birth ISSN: 0730-7659 Impact factor: 3.081
FIGURE 1Flow chart of the study sample
Baseline (T1) characteristics of the study sample (N = 1275)
| Control group (N = 434) | Intervention group (N = 841) |
| ||
|---|---|---|---|---|
| Age (years) | Mean (sd) | 31.65 (3.84) | 31.58 (4.24) | 0.78 |
| <25 | 19 (4.4) | 45 (5.4) | 0.71 | |
| 25‐35 | 321 (74.1) | 609 (72.5) | ||
| >35 | 93 (21.5) | 186 (22.1) | ||
| Missing | 1 | 1 | ||
| Parity | Primiparous | 209 (48.5) | 409 (48.9) | 0.88 |
| Multiparous | 222 (51.5) | 427 (51.1) | ||
| Missing | 3 | 5 | ||
| Ethnicity | Dutch | 375 (86.6) | 680 (80.9) | 0.01 |
| Non‐Dutch | 58 (13.4) | 161 (19.1) | ||
| Missing | 1 | 0 | ||
| Educational level | Low | 30 (6.9) | 55 (6.6) | 0.15 |
| Moderate | 130 (30.1) | 395 (35.6) | ||
| High | 272 (63.0) | 479 (57.8) | ||
| Missing | 2 | 12 | ||
| Relationship with father unborn child | Yes | 426 (98.6) | 810 (97.2) | 0.12 |
| No | 6 (1.4) | 23 (2.8) | ||
| Missing | 2 | 8 | ||
| Pregnancy‐specific anxiety (PRAQ‐R2) | Mean (sd) | 19.94 (5.83) | 20.14 (6.21) | 0.58 |
| Missing | 10 | 15 | ||
| Mother‐to‐infant bonding (MAAS) | Mean (sd) | 75.70 (5.81) | 76.21 (6.13) | 0.16 |
| Missing | 12 | 26 | ||
| General anxiety (STAI) | Mean (sd) | 9.75 (2.84) | 10.05 (2.90) | 0.08 |
| Missing | 5 | 12 | ||
| Depressive symptoms (EDS) | Mean (sd) | 5.48 (4.26) | 5.82 (4.02) | 0.16 |
| Missing | 7 | 21 |
Results are presented as N (%), unless stated otherwise
Effect of offering a third‐trimester routine ultrasound on pregnancy‐specific anxiety and mother‐to‐infant bonding obtained from linear mixed model analysis
| Control group (N = 434) | Intervention group (N = 841) | B (95% CI) |
| |
|---|---|---|---|---|
| Mean (sd) | Mean (sd) | |||
| Pregnancy‐specific anxiety sum score (PRAQ‐R2 T2) | ||||
| Unadjusted model | 19.74 (5.62) | 19.65 (6.05) | −0.09 (−0.78 to 0.60) | 0.81 |
| Final model | −0.31 (−0.74 to 0.11) | 0.15 | ||
| Mother‐to‐infant bonding sum score (MAAS T2) | ||||
| Unadjusted model | 74.42 (5.76) | 75.04 (5.67) | 0.65 (−0.07 to 1.37) | 0.08 |
| Final model | 0.37 (−0.18 to 0.92) | 0.18 | ||
In the unadjusted model, the crude associations are presented. In the final model, we adjusted for midwifery practice, baseline levels of our outcomes of interest, baseline levels of general anxiety, and depressive symptoms for both our outcomes of interest and parity and ethnicity when examining pregnancy‐specific anxiety. Sample sizes slightly differ per analysis because of missings on outcomes or confounding variables.
Effect of a third‐trimester routine ultrasound on pregnancy‐specific anxiety and mother‐to‐infant bonding: per‐protocol analysis
| Control group (N = 211) | Intervention group (N = 539) | B (95% CI) |
| |
|---|---|---|---|---|
| Mean (sd) | Mean (sd) | |||
| Pregnancy‐specific anxiety sum score (PRAQ‐R2 T2) | ||||
| Unadjusted model | 20.13 (5.60) | 19.33 (5.83) | −0.80 (−1.73 to 0.13) | 0.09 |
| Final model | −0.61 (−1.18 to −0.04) | 0.04 | ||
| Mother‐to‐infant bonding sum score (MAAS T2) | ||||
| Unadjusted model | 77.52 (5.86) | 78.23 (5.86) | 0.71 (−0.24 to 1.65) | 0.14 |
| Final model | 0.38 (−0.36 to 1.11) | 0.31 | ||
In the unadjusted model, the crude associations are presented. In the final model, we adjusted for midwifery practice, baseline levels of our outcomes of interest, baseline levels of general anxiety and depressive symptoms for both our outcomes of interest and parity and ethnicity when examining pregnancy‐specific anxiety. Sample sizes slightly differ per analysis because of missings on outcomes or confounding variables.
FIGURE 2Interaction of baseline level of mother‐to‐infant bonding with the intervention on mother‐to‐infant bonding at T2
FIGURE 3Interaction of baseline level of depressive symptoms with the intervention on mother‐to‐infant bonding at T2