Literature DB >> 34287701

How does sleep apnea impact outcomes following primary total hip arthroplasty for femoral neck fractures: a matched-control analysis.

Ivan J Golub1, Mitchell K Ng1, Charles A Conway1, Rushabh M Vakharia2, Lisa K Cannada3, Kevin K Kang1.   

Abstract

BACKGROUND: Cross-sectional studies have demonstrated that the prevalence of sleep apnea (SA) to be increasing within the United States. While studies have shown the association of SA and its association on complications following elective orthopedic procedures, well-powered studies investigating its impact in a traumatic setting are limited. The purpose of this study was to determine whether SA patients undergoing primary total hip arthroplasty (THA) for femoral neck fractures have higher rates of: (1) hospital lengths of stay (LOS); (2) readmissions; (3) complications; and (4) healthcare expenditures.
METHODS: The 100% Medicare Standard Analytical Files was queried from 2005 to 2014 for patients who sustained femoral neck fractures and were treated with primary THA. The study group consisted of patients with concomitant diagnoses of SA, whereas patients without SA served as controls. Study group patients were matched to controls in a 1:5 ratio by age, sex, and various comorbid conditions. Demographics of the cohorts were compared using Pearson's chi-squared analyses, and multivariate logistic regression analyses were used to calculate the odds (OR) of the effects of SA on postoperative outcomes. A p value less than 0.006 was considered to be statistically significant.
RESULTS: The final query yielded 24,936 patients within the study (n = 4166) and control (n = 20,770) cohorts. SA patients had significantly longer in-hospital LOS (6 vs. 5 days, p < 0.0001) but similar readmission rates (24.12 vs. 20.50%; OR: 1.03, p = 0.476). SA patients had significantly higher frequency and odds of developing medical complications (72.66 vs. 43.85%; OR: 1.57, p < 0.0001), and higher healthcare costs ($22,743.79 vs. $21,572.89, p < 0.0001).
CONCLUSION: SA is associated with longer in-hospital LOS, higher rates of complications and healthcare expenditures. This study is vital as it can allow orthopaedists to educate patients with SA on the potential complications which may occur following their procedure. LEVEL OF EVIDENCE: III.
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Femoral neck fractures; Medicare; Outcomes; Sleep apnea; Total hip arthroplasty

Year:  2021        PMID: 34287701     DOI: 10.1007/s00402-021-04070-0

Source DB:  PubMed          Journal:  Arch Orthop Trauma Surg        ISSN: 0936-8051            Impact factor:   3.067


  22 in total

Review 1.  Sleep apnea in total joint arthroplasty patients and the role for cardiac biomarkers for risk stratification: an exploration of feasibility.

Authors:  M Melanie Lyons; Nitin Y Bhatt; Elizabeth Kneeland-Szanto; Brendan T Keenan; Joanne Pechar; Branden Stearns; Nabil M Elkassabany; Stavros G Memtsoudis; Allan I Pack; Indira Gurubhagavatula
Journal:  Biomark Med       Date:  2016       Impact factor: 2.851

2.  Clinical and Administrative Databases Used in Lower Extremity Arthroplasty Research.

Authors:  Mitchell K Ng; Rushabh M Vakharia; Kevin J Bozic; John J Callaghan; Michael A Mont
Journal:  J Arthroplasty       Date:  2021-05-28       Impact factor: 4.757

3.  Comparison of Patient Demographics and Patient-Related Risk Factors for Infections After Primary Total Hip Arthroplasty for Acetabular Fractures.

Authors:  Matthew L Ciminero; Ivan J Golub; Angelo Mannino; Rushabh M Vakharia; Lisa K Cannada; Kevin K Kang
Journal:  J Am Acad Orthop Surg       Date:  2021-05-17       Impact factor: 3.020

Review 4.  Obstructive sleep apnea syndrome and perioperative complications: a systematic review of the literature.

Authors:  Tajender S Vasu; Ritu Grewal; Karl Doghramji
Journal:  J Clin Sleep Med       Date:  2012-04-15       Impact factor: 4.062

Review 5.  Updates on definition, consequences, and management of obstructive sleep apnea.

Authors:  John G Park; Kannan Ramar; Eric J Olson
Journal:  Mayo Clin Proc       Date:  2011-06       Impact factor: 7.616

6.  An estimate of the worldwide prevalence and disability associated with osteoporotic fractures.

Authors:  O Johnell; J A Kanis
Journal:  Osteoporos Int       Date:  2006-09-16       Impact factor: 4.507

7.  Increased carotid intima-media thickness and serum inflammatory markers in obstructive sleep apnea.

Authors:  Kenji Minoguchi; Takuya Yokoe; Toshiyuki Tazaki; Hideko Minoguchi; Akihiko Tanaka; Naruhito Oda; Shinji Okada; Shin Ohta; Hirokuni Naito; Mitsuru Adachi
Journal:  Am J Respir Crit Care Med       Date:  2005-09-01       Impact factor: 21.405

Review 8.  Obstructive sleep apnea is a common disorder in the population-a review on the epidemiology of sleep apnea.

Authors:  Karl A Franklin; Eva Lindberg
Journal:  J Thorac Dis       Date:  2015-08       Impact factor: 2.895

Review 9.  Prevalence of obstructive sleep apnea in the general population: A systematic review.

Authors:  Chamara V Senaratna; Jennifer L Perret; Caroline J Lodge; Adrian J Lowe; Brittany E Campbell; Melanie C Matheson; Garun S Hamilton; Shyamali C Dharmage
Journal:  Sleep Med Rev       Date:  2016-07-18       Impact factor: 11.609

10.  OSA Is a Risk Factor for Recurrent VTE.

Authors:  Alberto Alonso-Fernández; Angela García Suquia; Mónica de la Peña; Raquel Casitas; Javier Pierola; Antonia Barceló; Joan B Soriano; Carmen Fernández-Capitán; Elizabet Martinez-Ceron; Miguel Carrera; Francisco García-Río
Journal:  Chest       Date:  2016-07-21       Impact factor: 9.410

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  1 in total

1.  Effects of Hypercarbia on Lower Extremity Primary Total Joint Replacement Infections.

Authors:  Teigen Goodeill; Justin Than; Olivia Pipitone; Jason Lin; Nicholas Tedesco
Journal:  Cureus       Date:  2022-06-18
  1 in total

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