| Literature DB >> 26925513 |
M Melanie Lyons1,2, Nitin Y Bhatt3, Elizabeth Kneeland-Szanto1, Brendan T Keenan1, Joanne Pechar4, Branden Stearns1, Nabil M Elkassabany5, Stavros G Memtsoudis6, Allan I Pack1, Indira Gurubhagavatula1,7.
Abstract
Obstructive sleep apnea (OSA) is highly prevalent in patients undergoing total joint arthroplasty (TJA) and is a major risk factor for postoperative cardiovascular complications and death. Recognizing this, the American Society of Anesthesiologists urges clinicians to implement special considerations in the perioperative care of OSA patients. However, as the volume of patients presenting for TJA increases, resources to implement these recommendations are limited. This necessitates mechanisms to efficiently risk stratify patients having OSA who may be susceptible to post-TJA cardiovascular complications. We explore the role of perioperative measurement of cardiac troponins (cTns) and brain natriuretic peptides (BNPs) in helping determine which OSA patients are at increased risk for post-TJA cardiovascular-related morbidity.Entities:
Keywords: brain natriuretic peptide; obstructive sleep apnea; postoperative complications; total joint arthroplasty; troponin
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Year: 2016 PMID: 26925513 PMCID: PMC5493965 DOI: 10.2217/bmm.16.1
Source DB: PubMed Journal: Biomark Med ISSN: 1752-0363 Impact factor: 2.851