Literature DB >> 34280247

Injection time related to intraocular pressure using a CO2 driven preloaded injector: An experimental laboratory study.

Jan N Weindler1, Tadas Naujokaitis1, Sonja K Schickhardt1, Ramin Khoramnia1, Gerd U Auffarth1.   

Abstract

PURPOSE: Experimental study to measure the intraocular lens (IOL) injection time and injection speed at different intraocular pressure (IOP) settings when using the AutonoMe® injector.
METHODS: In this experimental study, following phacoemulsification in porcine cadaver eyes, a trocar was inserted at pars plana with a connected infusion and IOPs of 20, 50 and 80 mmHg were generated by altering the infusion height. Twelve CO2 gas-driven injectors were used to implant an IOL via a corneal incision of 2.2 mm. For each IOP setting, the duration of the IOL injection and the injection speed was measured by analyzing a video recording of the procedure.
RESULTS: The mean ±SD injection time (seconds) was 4.47±0.50 at 20 mmHg, 4.98±0.55 at 50 mmHg and 5.47±0.20 at 80 mmHg. The mean ±SD injection speed (millimeters per seconds) was 1.36±0.15 at 20 mmHg, 1.22±0.14 at 50 mmHg and 1.10±0.04 at 80 mmHg. There was a significant (p<0.05) difference between the 20 and 80 mmHg groups in mean injection duration and injection speed.
CONCLUSION: The CO2 gas driven injector allows a safe IOL injection even at elevated IOP. Although the implantation time is slightly extended at higher IOPs, this does not seem to be clinically relevant. No IOL damage was observed at these pressure settings.

Entities:  

Year:  2021        PMID: 34280247     DOI: 10.1371/journal.pone.0254901

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


  17 in total

1.  Resistance force for intraocular lens insertion through lens cartridges and syringe-type injectors.

Authors:  Masahiko Usui; Takao Tanaka
Journal:  J Cataract Refract Surg       Date:  2015-08       Impact factor: 3.351

2.  Intraoperative intraocular pressure fluctuation during standard phacoemulsification in real human patients.

Authors:  Libor Hejsek; Jana Kadlecova; Martin Sin; Vera Velika; Nada Jiraskova
Journal:  Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub       Date:  2018-11-06       Impact factor: 1.245

3.  Intraocular pressure during phacoemulsification.

Authors:  Christopher Khng; Mark Packer; I Howard Fine; Richard S Hoffman; Fernando B Moreira
Journal:  J Cataract Refract Surg       Date:  2006-02       Impact factor: 3.351

4.  Pressure-volume relation for the living human eye.

Authors:  D M Silver; O Geyer
Journal:  Curr Eye Res       Date:  2000-02       Impact factor: 2.424

5.  Preloaded and non-preloaded intraocular lens delivery system and characteristics: human and porcine eyes trial.

Authors:  Byunghoon Chung; Hun Lee; Moonjung Choi; Kyoung Yul Seo; Eung Kweon Kim; Tae-Im Kim
Journal:  Int J Ophthalmol       Date:  2018-01-18       Impact factor: 1.779

6.  Comparison of intraocular pressure profiles during cataract surgery by phacoemulsification and extracapsular cataract extraction.

Authors:  Aharon Grinbaum; Michael Blumenthal; Ehud Assia
Journal:  Ophthalmic Surg Lasers Imaging       Date:  2003 May-Jun

7.  A 10 year retrospective survey of cataract surgery and endophthalmitis in a single eye unit: injectable lenses lower the incidence of endophthalmitis.

Authors:  E Mayer; D Cadman; P Ewings; J M Twomey; R H Gray; K G Claridge; K N Hakin; A K Bates
Journal:  Br J Ophthalmol       Date:  2003-07       Impact factor: 4.638

8.  Intraocular pressure and calculated diastolic ocular perfusion pressure during three simulated steps of phacoemulsification in vivo.

Authors:  Yune Zhao; Xingyu Li; Aizhu Tao; Jianhua Wang; Fan Lu
Journal:  Invest Ophthalmol Vis Sci       Date:  2009-01-24       Impact factor: 4.799

9.  The impact of a preloaded intraocular lens delivery system on operating room efficiency in routine cataract surgery.

Authors:  Jason J Jones; Jeffrey Chu; Jacob Graham; Serge Zaluski; Guillermo Rocha
Journal:  Clin Ophthalmol       Date:  2016-06-17

10.  Intraocular pressure and its normal range adjusted for ocular and systemic parameters. The Beijing Eye Study 2011.

Authors:  Ya Xing Wang; Liang Xu; Wen Bin Wei; Jost B Jonas
Journal:  PLoS One       Date:  2018-05-17       Impact factor: 3.240

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