BACKGROUND: The Taiwan Society of Cardiology (TSOC) has established multicenter registries for coronary artery disease (CAD) to investigate clinical characteristics, management and risks for mortality. However, the impacts of newly-emerged evidence-based therapies, including the use of drug-eluting stents (DESs), on patients with CAD in Taiwan remain unclear. METHODS: The Tri-Service General Hospital-Coronary Heart Disease (TSGH-CHD) registry is a single-center, prospective, longitudinal registry in Taiwan containing data from 2014-2016. Individuals who were admitted for coronary angiography were enrolled. Patient profiles, management and in-hospital outcome data were collected. RESULTS: We included 3352 patients: 2349 with stable angina and 1003 with acute coronary syndrome (ACS). In the stable angina group, both patients receiving stenting and those receiving medical treatment had a 0.7% mortality rate; DESs were used in 70.4% of the patients receiving stenting. In the ACS group, the patients receiving stenting and those receiving medical treatment had a 4.9% and 10.7% mortality rate, respectively; DESs were used in 63.1% of the patients receiving stenting. In the 2008-2010 Taiwan ACS registry, DESs were used in only 28% of all stenting procedures, and the estimated hospital mortality rate was 1.8%. Multivariate analysis indicated that older age, prior stroke, and cardiogenic shock on admission were associated with an increased risk of in-hospital mortality in the ACS group. CONCLUSIONS: Compared with the Taiwan ACS cohort, the TSGH-CHD registry revealed increased DES use and increased disease complexity and severity after 2010. Although unlikely to significantly improve survival, interventionists seemed to perform high-risk procedures for complex CAD more often in the new DES era.
BACKGROUND: The Taiwan Society of Cardiology (TSOC) has established multicenter registries for coronary artery disease (CAD) to investigate clinical characteristics, management and risks for mortality. However, the impacts of newly-emerged evidence-based therapies, including the use of drug-eluting stents (DESs), on patients with CAD in Taiwan remain unclear. METHODS: The Tri-Service General Hospital-Coronary Heart Disease (TSGH-CHD) registry is a single-center, prospective, longitudinal registry in Taiwan containing data from 2014-2016. Individuals who were admitted for coronary angiography were enrolled. Patient profiles, management and in-hospital outcome data were collected. RESULTS: We included 3352 patients: 2349 with stable angina and 1003 with acute coronary syndrome (ACS). In the stable angina group, both patients receiving stenting and those receiving medical treatment had a 0.7% mortality rate; DESs were used in 70.4% of the patients receiving stenting. In the ACS group, the patients receiving stenting and those receiving medical treatment had a 4.9% and 10.7% mortality rate, respectively; DESs were used in 63.1% of the patients receiving stenting. In the 2008-2010 Taiwan ACS registry, DESs were used in only 28% of all stenting procedures, and the estimated hospital mortality rate was 1.8%. Multivariate analysis indicated that older age, prior stroke, and cardiogenic shock on admission were associated with an increased risk of in-hospital mortality in the ACS group. CONCLUSIONS: Compared with the Taiwan ACS cohort, the TSGH-CHD registry revealed increased DES use and increased disease complexity and severity after 2010. Although unlikely to significantly improve survival, interventionists seemed to perform high-risk procedures for complex CAD more often in the new DES era.
Authors: Ph Gabriel Steg; Deepak L Bhatt; Peter W F Wilson; Ralph D'Agostino; E Magnus Ohman; Joachim Röther; Chiau-Suong Liau; Alan T Hirsch; Jean-Louis Mas; Yasuo Ikeda; Michael J Pencina; Shinya Goto Journal: JAMA Date: 2007-03-21 Impact factor: 56.272
Authors: Manel Sabate; Angel Cequier; Andrés Iñiguez; Antonio Serra; Rosana Hernandez-Antolin; Vicente Mainar; Marco Valgimigli; Maurizio Tespili; Pieter den Heijer; Armando Bethencourt; Nicolás Vazquez; Joan Antoni Gómez-Hospital; José Antonio Baz; Victoria Martin-Yuste; Robert-Jan van Geuns; Fernando Alfonso; Pascual Bordes; Matteo Tebaldi; Monica Masotti; Antonio Silvestro; Bianca Backx; Salvatore Brugaletta; Gerrit Anne van Es; Patrick W Serruys Journal: Lancet Date: 2012-09-03 Impact factor: 79.321
Authors: Emmanuel Sorbets; Nicola Greenlaw; Roberto Ferrari; Ian Ford; Kim M Fox; Jean-Claude Tardif; Michal Tendera; Philippe Gabriel Steg Journal: Clin Cardiol Date: 2017-05-31 Impact factor: 2.882
Authors: Kang Ling Wang; Carl Roobottom; Jason E Smith; Steve Goodacre; Katherine Oatey; Rachel O'Brien; Robert F Storey; Nick Curzen; Liza Keating; Attila Kardos; Dirk Felmeden; Praveen Thokala; Nicholas L Mills; David E Newby; Alasdair J Gray Journal: Eur Heart J Acute Cardiovasc Care Date: 2022-07-21