Literature DB >> 34250146

Incidental Diagnosis of Multiple Paragangliomas by Ga-68 DOTANOC Positron Emission Tomography-Computed Tomography.

Vivek Kumar Saini1, Akshay Kumar1, Aftab Hasan Nazar1, Manish Ora1, Sanjay Gambhir1.   

Abstract

A 65-year-old man presented with intermittent abdominal pain for three months. Abdominal ultrasonography revealed a mass in the body of the pancreas. Moreover, abdominal contrast-enhancing computed tomography revealed a homogenously enhancing mass in the body of the pancreas. Scan findings were in favor of the neuroendocrine tumor, and the serum chromogranin level was slightly raised (111.9 ng/ml, normal <98). He had no history of vomiting, jaundice, melena, hematemesis, constipation, diarrhea, weight gain, weight loss, loss of appetite, and fever. He also had no symptoms related to the excessive production of catecholamines, such as hypertension. The patient was referred for Ga-68 DOTANOC positron emission tomography-computed tomography (Ga-68 DOTANOC PET-CT) for further evaluation. The scan was done to rule out metastatic disease or other synchronous lesions to plan surgical excision. The Ga-68 DOTANOC PET-CT revealed a pancreatic lesion with no other abdominal lesions. We noted multiple tracer avid soft tissue lesions on both sides of the neck that were not diagnosed previously. This case report demonstrates a rare case with multiple paragangliomas diagnosed by the Ga-68 DOTANOC PET-CT. This finding could lead to changes in patient management.
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Entities:  

Keywords:  Ga-68 DOTANOC; Multiple Paraganglioma; PET/CT

Year:  2021        PMID: 34250146      PMCID: PMC8255528          DOI: 10.22038/AOJNMB.2021.17883

Source DB:  PubMed          Journal:  Asia Ocean J Nucl Med Biol        ISSN: 2322-5718


  14 in total

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Authors:  J K Ramage; A H G Davies; J Ardill; N Bax; M Caplin; A Grossman; R Hawkins; A M McNicol; N Reed; R Sutton; R Thakker; S Aylwin; D Breen; K Britton; K Buchanan; P Corrie; A Gillams; V Lewington; D McCance; K Meeran; A Watkinson
Journal:  Gut       Date:  2005-06       Impact factor: 23.059

2.  Paragangliomas: assessment of prognosis by histologic, immunohistochemical, and ultrastructural techniques.

Authors:  K E Kliewer; D R Wen; P A Cancilla; A J Cochran
Journal:  Hum Pathol       Date:  1989-01       Impact factor: 3.466

3.  Multiple paragangliomas of the head and neck.

Authors:  G Magliulo; F Zardo; S Varacalli; R D'Amico
Journal:  An Otorrinolaringol Ibero Am       Date:  2003

Review 4.  Genetics of pheochromocytomas and paragangliomas.

Authors:  Giuseppe Opocher; Francesca Schiavi
Journal:  Best Pract Res Clin Endocrinol Metab       Date:  2010-12       Impact factor: 4.690

5.  Staging and functional characterization of pheochromocytoma and paraganglioma by 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography.

Authors:  Henri J L M Timmers; Clara C Chen; Jorge A Carrasquillo; Millie Whatley; Alexander Ling; Graeme Eisenhofer; Kathryn S King; Jyotsna U Rao; Robert A Wesley; Karen T Adams; Karel Pacak
Journal:  J Natl Cancer Inst       Date:  2012-04-18       Impact factor: 13.506

Review 6.  Pheochromocytoma: an imaging chameleon.

Authors:  Michael A Blake; Mannudeep K Kalra; Michael M Maher; Dushyant V Sahani; Ann T Sweeney; Peter R Mueller; Peter F Hahn; Giles W Boland
Journal:  Radiographics       Date:  2004-10       Impact factor: 5.333

Review 7.  Metabologenomics of Phaeochromocytoma and Paraganglioma: An Integrated Approach for Personalised Biochemical and Genetic Testing.

Authors:  Graeme Eisenhofer; Barbara Klink; Susan Richter; Jacques Wm Lenders; Mercedes Robledo
Journal:  Clin Biochem Rev       Date:  2017-04

Review 8.  European Society of Endocrinology Clinical Practice Guideline for long-term follow-up of patients operated on for a phaeochromocytoma or a paraganglioma.

Authors:  P F Plouin; L Amar; O M Dekkers; M Fassnacht; A P Gimenez-Roqueplo; J W M Lenders; C Lussey-Lepoutre; O Steichen
Journal:  Eur J Endocrinol       Date:  2016-05       Impact factor: 6.664

Review 9.  Pheochromocytoma and Paraganglioma: From Epidemiology to Clinical Findings.

Authors:  Nurcihan Aygun; Mehmet Uludag
Journal:  Sisli Etfal Hastan Tip Bul       Date:  2020-06-03

10.  Challenges in the surgical treatment of undiagnosed functional paragangliomas: A case report.

Authors:  Liangyuan Lu; Zhanmin Yang; Guyue Zhang; Bin An; Yanjun Lin; Xiangli Zheng
Journal:  Medicine (Baltimore)       Date:  2018-09       Impact factor: 1.817

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