Literature DB >> 34236671

Efficacy and Safety of 10 kHz Spinal Cord Stimulation Using Cervical and Thoracic Leads: A Single-Center Retrospective Experience.

Gernot Surges1, Joachim Paulus2, Theresa Blaß2, Kerstin Mendryscha2, Martin Bettag2, Anand Rotte3.   

Abstract

INTRODUCTION: Spinal cord stimulation (SCS) with lower thoracic leads has been studied extensively. However, the evidence base for cervical SCS is less well developed, and reports of multiarea SCS lead placement are uncommon. Therefore, this single-center retrospective study evaluated outcomes from 10-kHz SCS with cervical or combined cervical and thoracic lead placement.
METHOD: All patients that underwent a 10-kHz SCS trial with either cervical or combined cervical and thoracic lead placement between 2015 and 2020 were included in our study. We reviewed patient's charts for demographic information, lead placement, and pain scores up to 48 months after implantation.
RESULTS: Of the 105 patients that underwent a 10-kHz SCS trial during the review period, 92 (88%) had back/neck or extremity pain that responded to therapy (≥ 50% pain relief from baseline) and received a permanent system. Sixty-two of these patients (67%) were implanted with combined cervical and thoracic leads, while 30 (33%) received cervical-only leads. Pain relief in both regions exceeded 60% at most visits throughout the 48-month study period. Throughout follow-up, the responder rate in both pain areas was consistently ≥ 70%. No unexpected adverse events occurred.
CONCLUSION: The 10-kHz SCS provided effective and durable pain relief with either cervical or combined cervical and thoracic leads. The efficacy and safety profile of both applications appears to be comparable to lower thoracic SCS. Our results suggest that 10-kHz SCS is a useful paresthesia-free therapeutic option for chronic neuropathic pain originating in the cervical area, as well as more complex multiarea pain presentations.

Entities:  

Keywords:  10 kHz SCS; Cervical SCS; Chronic pain; Multiarea SCS; Thoracic SCS

Year:  2021        PMID: 34236671     DOI: 10.1007/s40122-021-00287-4

Source DB:  PubMed          Journal:  Pain Ther


  38 in total

Review 1.  Evidence Gaps in the Use of Spinal Cord Stimulation for Treating Chronic Spine Conditions.

Authors:  David A Provenzano; Kasra Amirdelfan; Leonardo Kapural; B Todd Sitzman
Journal:  Spine (Phila Pa 1976)       Date:  2017-07-15       Impact factor: 3.468

2.  A Systematic Literature Review of Spine Neurostimulation Therapies for the Treatment of Pain.

Authors:  Timothy R Deer; Jay S Grider; Tim J Lamer; Jason E Pope; Steven Falowski; Corey W Hunter; David A Provenzano; Konstantin V Slavin; Marc Russo; Alexios Carayannopoulos; Jay M Shah; Michael E Harned; Jonathan M Hagedorn; Robert B Bolash; Jeff E Arle; Leo Kapural; Kasra Amirdelfan; Sameer Jain; Liong Liem; Jonathan D Carlson; Mark N Malinowski; Markus Bendel; Ajax Yang; Rohit Aiyer; Ali Valimahomed; Ajay Antony; Justin Craig; Michael A Fishman; Adnan A Al-Kaisy; Nick Christelis; Richard W Rosenquist; Robert M Levy; Nagy Mekhail
Journal:  Pain Med       Date:  2020-11-07       Impact factor: 3.750

3.  Mapping of sensory responses to epidural stimulation of the intraspinal neural structures in man.

Authors:  G Barolat; F Massaro; J He; S Zeme; B Ketcik
Journal:  J Neurosurg       Date:  1993-02       Impact factor: 5.115

4.  State of the field survey: spinal cord stimulator use by academic pain medicine practices.

Authors:  Christopher Gharibo; Gary Laux; Brian R Forzani; Christopher Sellars; Eric Kim; Shengping Zou
Journal:  Pain Med       Date:  2013-10-18       Impact factor: 3.750

5.  Explant rates of electrical neuromodulation devices in 1177 patients in a single center over an 11-year period.

Authors:  Adnan Al-Kaisy; Jonathan Royds; Omar Al-Kaisy; Stefano Palmisani; David Pang; Tom Smith; Nicholas Padfield; Stephany Harris; Samuel Wesley; Thomas Lamar Yearwood; Stephen Ward
Journal:  Reg Anesth Pain Med       Date:  2020-08-26       Impact factor: 6.288

6.  Less Pain Relief, More Depression, and Female Sex Correlate With Spinal Cord Stimulation Explants.

Authors:  Julia Slyer; Samae Scott; Breanna Sheldon; Maria Hancu; Cheyanne Bridger; Julie G Pilitsis
Journal:  Neuromodulation       Date:  2019-08-19

7.  The Neurostimulation Appropriateness Consensus Committee (NACC) Safety Guidelines for the Reduction of Severe Neurological Injury.

Authors:  Timothy R Deer; Tim J Lamer; Jason E Pope; Steven M Falowski; David A Provenzano; Konstantin Slavin; Stanley Golovac; Jeffrey Arle; Joshua M Rosenow; Kayode Williams; Porter McRoberts; Samer Narouze; Sam Eldabe; Shivanand P Lad; Jose A De Andrés; Eric Buchser; Philippe Rigoard; Robert M Levy; Brian Simpson; Nagy Mekhail
Journal:  Neuromodulation       Date:  2017-01-02

8.  The appropriate use of neurostimulation: avoidance and treatment of complications of neurostimulation therapies for the treatment of chronic pain. Neuromodulation Appropriateness Consensus Committee.

Authors:  Timothy R Deer; Nagy Mekhail; David Provenzano; Jason Pope; Elliot Krames; Simon Thomson; Lou Raso; Allen Burton; Jose DeAndres; Eric Buchser; Asokumar Buvanendran; Liong Liem; Krishna Kumar; Syed Rizvi; Claudio Feler; David Abejon; Jack Anderson; Sam Eldabe; Philip Kim; Michael Leong; Salim Hayek; Gladstone McDowell; Lawrence Poree; Elizabeth S Brooks; Tory McJunkin; Paul Lynch; Leo Kapural; Robert D Foreman; David Caraway; Ken Alo; Samer Narouze; Robert M Levy; Richard North
Journal:  Neuromodulation       Date:  2014-08

Review 9.  Effectiveness of cervical spinal cord stimulation for the management of chronic pain.

Authors:  Timothy R Deer; Ioannis M Skaribas; Nameer Haider; John Salmon; Chong Kim; Christopher Nelson; Jerry Tracy; Anthony Espinet; Todd E Lininger; Robert Tiso; Melinda A Archacki; Stephanie N Washburn
Journal:  Neuromodulation       Date:  2013-09-24

10.  Spinal cord stimulation in chronic neuropathic pain: mechanisms of action, new locations, new paradigms.

Authors:  Elbert A Joosten; Glenn Franken
Journal:  Pain       Date:  2020-09       Impact factor: 6.961

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