Literature DB >> 34201950

Dietary Antiplatelets: A New Perspective on the Health Benefits of the Water-Soluble Tomato Concentrate Fruitflow®.

Niamh O'Kennedy1, Ruedi Duss2, Asim K Duttaroy3.   

Abstract

Our understanding of platelet functionality has undergone a sea change in the last decade. No longer are platelets viewed simply as regulators of haemostasis; they are now acknowledged to be pivotal in coordinating the inflammatory and immune responses. This expanded role for platelets brings new opportunities for controlling a range of health conditions, targeting platelet activation and their interactions with other vascular cells. Antiplatelet drugs may be of wider utility than ever expected but often cause platelet suppression too strong to be used out of clinical settings. Dietary antiplatelets represent a nutritional approach that can be efficacious while safe for general use. In this review, we discuss potential new uses for dietary antiplatelets outside the field of cardiovascular health, with specific reference to the water-soluble tomato extract Fruitflow®. Its uses in different aspects of inflammation and immune function are discussed, highlighting exercise-induced inflammation, mediating the effects of air pollution, and controlling thrombotic aspects of the immune response. Potential future developments in women's health, erectile dysfunction, and the allergic response indicate how broad the utility of dietary antiplatelets can be.

Entities:  

Keywords:  dietary antiplatelet; immunothrombosis; inflammation; particulate air pollution; platelet activation; platelet function; platelet hyperactivity; platelet-leukocyte aggregates; water-soluble tomato extract

Year:  2021        PMID: 34201950     DOI: 10.3390/nu13072184

Source DB:  PubMed          Journal:  Nutrients        ISSN: 2072-6643            Impact factor:   5.717


  74 in total

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Authors:  J E Smith
Journal:  Br J Sports Med       Date:  2003       Impact factor: 13.800

Review 2.  Platelets in atherosclerosis.

Authors:  D Lievens; P von Hundelshausen
Journal:  Thromb Haemost       Date:  2011-10-20       Impact factor: 5.249

Review 3.  Benefits of Exercise in the Older Population.

Authors:  Juan Galloza; Brenda Castillo; William Micheo
Journal:  Phys Med Rehabil Clin N Am       Date:  2017-11       Impact factor: 1.784

4.  Acute and Chronic Exercise in Animal Models.

Authors:  Vu Thi Thu; Hyoung Kyu Kim; Jin Han
Journal:  Adv Exp Med Biol       Date:  2017       Impact factor: 2.622

5.  American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise.

Authors:  Carol Ewing Garber; Bryan Blissmer; Michael R Deschenes; Barry A Franklin; Michael J Lamonte; I-Min Lee; David C Nieman; David P Swain
Journal:  Med Sci Sports Exerc       Date:  2011-07       Impact factor: 5.411

Review 6.  Circulating Platelets as Mediators of Immunity, Inflammation, and Thrombosis.

Authors:  Milka Koupenova; Lauren Clancy; Heather A Corkrey; Jane E Freedman
Journal:  Circ Res       Date:  2018-01-19       Impact factor: 17.367

7.  Tomatoes have natural anti-thrombotic effects.

Authors:  J Yamamoto; T Taka; K Yamada; Y Ijiri; M Murakami; Y Hirata; A Naemura; M Hashimoto; T Yamashita; K Oiwa; J Seki; H Suganuma; T Inakuma; T Yoshida
Journal:  Br J Nutr       Date:  2003-12       Impact factor: 3.718

8.  Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015.

Authors:  Aaron J Cohen; Michael Brauer; Richard Burnett; H Ross Anderson; Joseph Frostad; Kara Estep; Kalpana Balakrishnan; Bert Brunekreef; Lalit Dandona; Rakhi Dandona; Valery Feigin; Greg Freedman; Bryan Hubbell; Amelia Jobling; Haidong Kan; Luke Knibbs; Yang Liu; Randall Martin; Lidia Morawska; C Arden Pope; Hwashin Shin; Kurt Straif; Gavin Shaddick; Matthew Thomas; Rita van Dingenen; Aaron van Donkelaar; Theo Vos; Christopher J L Murray; Mohammad H Forouzanfar
Journal:  Lancet       Date:  2017-04-10       Impact factor: 79.321

Review 9.  Platelets and Intravascular Immunity: Guardians of the Vascular Space During Bloodstream Infections and Sepsis.

Authors:  Braedon McDonald; Mary Dunbar
Journal:  Front Immunol       Date:  2019-10-11       Impact factor: 7.561

10.  Acute high-intensity interval rowing increases thrombin generation in healthy men.

Authors:  Matthew J Sedgwick; Matthew Thompson; Jack Garnham; Alice E Thackray; Laura A Barrett; Matthew Powis; David J Stensel
Journal:  Eur J Appl Physiol       Date:  2016-04-12       Impact factor: 3.078

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  3 in total

1.  Four-Week Supplementation of Water-Soluble Tomato Extract Attenuates Platelet Function in Chinese Healthy Middle-Aged and Older Individuals: A Randomized, Double-Blinded, and Crossover Clinical Trial.

Authors:  Zezhong Tian; Die Fan; Kongyao Li; Dan Zhao; Ying Liang; Qiuhua Ji; Xiaoli Gao; Xilin Ma; Yimin Zhao; Yuheng Mao; Huicui Meng; Yan Yang
Journal:  Front Nutr       Date:  2022-06-01

Review 2.  Scientific Evidence of the Beneficial Effects of Tomato Products on Cardiovascular Disease and Platelet Aggregation.

Authors:  Montaña Cámara; Virginia Fernández-Ruiz; María-Cortes Sánchez-Mata; Rosa M Cámara; Laura Domínguez; Howard D Sesso
Journal:  Front Nutr       Date:  2022-03-15

3.  Water-soluble tomato concentrate modulates shear-induced platelet aggregation and blood flow in vitro and in vivo.

Authors:  Lu Liu; Shunli Xiao; Yilin Wang; Yufang Wang; Lei Liu; Zhengxiao Sun; Qian Zhang; Xiaojie Yin; Fulong Liao; Yun You; Xuguang Zhang
Journal:  Front Nutr       Date:  2022-09-02
  3 in total

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