| Literature DB >> 34182593 |
Julian C Jamison1, Donald Bundy2, Dean T Jamison3, Jacob Spitz4, Stéphane Verguet5.
Abstract
OBJECTIVE: Countries have adopted different approaches, at different times, to reduce the transmission of coronavirus disease 2019 (COVID-19). Cross-country comparison could indicate the relative efficacy of these approaches. We assess various nonpharmaceutical interventions (NPIs), comparing the effects of voluntary behavior change and of changes enforced via official regulations, by examining their impacts on subsequent death rates. DATA SOURCES: Secondary data on COVID-19 deaths from 13 European countries, over March-May 2020. STUDYEntities:
Keywords: SARS-CoV-2; Western Europe; lockdown; nonpharmaceutical interventions; salience; voluntary behavior change
Mesh:
Year: 2021 PMID: 34182593 PMCID: PMC8441808 DOI: 10.1111/1475-6773.13688
Source DB: PubMed Journal: Health Serv Res ISSN: 0017-9124 Impact factor: 3.734
Summary statistics on COVID‐related deaths and timing of measures of voluntary behavior and government‐mandated regulations, for 13 European countries, March–May 2020
| Country | Total number of deaths | Total number of deaths per million population | Date of | Date mobility falls | Date mobility fall impacts deaths | Date national stay‐at‐home restrictions announced | Date national stay‐at‐home restrictions impact deaths | Number of days of data |
|---|---|---|---|---|---|---|---|---|
| Austria | 628 | 71 | 24 March | 11 March | NA | 6 March | 22–26 March | 56 |
| Belgium | 8959 | 784 | 19 March | 12 March | 28 March–1 April | 18 March | 3–7 April | 61 |
| Denmark | 537 | 93 | 23 March | 12 March | 28 March–1 April | 13 March | 29 March–2 April | 57 |
| France | 27 529 | 411 | 08 March | 12 March | 28 March–1 April | 17 March | 2–6 April | 72 |
| Germany | 7881 | 95 | 18 March | 9 March | NA | 9 March | 25–29 March | 62 |
| Ireland | 1518 | 313 | 27 March | 11 March | 27–31 March | 26 March | 11–15 April | 53 |
| Italy | 31 610 | 523 | 01 March | 24 February | 11–15 March | 10 March | 26–30 March | 79 |
| the Netherlands | 5643 | 327 | 16 March | 10 March | 26–30 March | 12 March | 28 March–1 April | 64 |
| Portugal | 1190 | 116 | 23 March | 12 March | 28 March–1 April | 19 March | 4–8 April | 57 |
| Spain | 27 563 | 590 | 08 March | 11 March | 27–31 March | 14 March | 30 March–3 April | 72 |
| Sweden | 3646 | 358 | 23 March | 11 March | 27–31 March | NA | NA | 57 |
| Switzerland | 1594 | 187 | 19 March | 10 March | 26–30 March | 17 March | 2–6 April | 61 |
| United Kingdom | 33 998 | 511 | 14 March | 12 March | 28 March–1 April | 23 March | 8–12 April | 66 |
Note: Deaths data are cumulative up to and including 16 May. We describe policy changes as taking effect over a 5‐day date range because our model uses a 5‐day rolling average. Date t 0 denotes the date at which the 5‐day rolling average reached five deaths, which we define as the start of the epidemic.
FIGURE 1Change in mobility trends (February–May 2020) in Spain, Sweden, and the United Kingdom [Color figure can be viewed at wileyonlinelibrary.com]
FIGURE 2Evolution of the daily deaths since t 0 (the date at which the 5‐day moving average reaches five deaths) in Spain, Sweden, and the United Kingdom [Color figure can be viewed at wileyonlinelibrary.com]
Effect of observed mobility and government closure on daily change in deaths, for 13 European countries, March–May 2020
| Model I (18‐day lag) | Model II (17‐day lag) | Model III (19‐day lag) | Model IV (continuous) | |
|---|---|---|---|---|
| Days from | −0.88 | −0.86 | −0.90 | −0.83 |
| [−1.10, −0.67] | [−1.06, −0.67] | [−1.10, −0.70] | [−1.05, −0.61] | |
| Days from | 0.009 | 0.008 | 0.009 | 0.008 |
| [0.006, 0.011] | [0.006, 0.010] | [0.006, 0.11] | [0.006, 0.107] | |
| Binary mobility | −9.2 | −10.2 | −9.0 | |
| [−14.0, −4.5] | [−14.7, −5.7] | [−12.7, −5.4] | ||
| Continuous mobility | −8.5 | |||
| [−16.0, −1.1] | ||||
| Binary closure | −14.0 | −15.2 | −13.1 | |
| [−17.2, −10.8] | [−18.7, −11.7] | [−15.5, −10.7] | ||
| Continuous closure | −22.1 | |||
| [−27.4, −16.9] | ||||
| Percent of population older than 65 | −0.18 | −0.17 | −0.17 | −0.13 |
| [−0.42, 0.06] | [−0.41, 0.06] | [−0.45, 0.10] | [−0.67, 0.41] | |
| Population density | 0.001 | 0.001 | 0.001 | −0.003 |
| [−0.004, 0.007] | [−0.004, 0.007] | [−0.004, 0.006] | [−0.010, 0.004] | |
| Number of acute care beds, per 100 000 people | 0.002 | 0.002 | 0.002 | 0.004 |
| [−0.005, 0.009] | [−0.005, 0.009] | [−0.005, 0.008] | [−0.004, 0.012] | |
| Date of | −0.21 | −0.20 | −0.21 | −0.34 |
| [−0.28, −0.14] | [−0.27, −0.13] | [−0.29, −0.13] | [−0.45, −0.24] | |
| Number of observations | 778 | 778 | 778 | 776 |
Note: 95% Confidence intervals are presented in square brackets. Standard errors are clustered at the country level. The unit of observation is a country‐day: 1 day of data for a specific country. Observed mobility is the binary measure based off Google mobility data; continuous mobility is a measure calculated by summing the same three measures of the Google Mobility Index and normalizing across countries; binary closure is our binary variable based on the Oxford Policy Tracker index for stay‐at‐home restrictions; and continuous closure is a measure calculated by summing all eight “containment and closure” categories in the Oxford Policy Tracker and normalizing across countries. We make one small change to the Oxford data: defining the German lockdown as being nationwide instead of regional. N is lower in Model IV because the lagged mobility data are only available for Italy from the third day of the epidemic. Model IV assumes an average 18‐day lag for mortality, like Model I.
Significant at 5% level.
** Significant at 1% level.
Significant at 0.1% level.
Disaggregated impact of the various nonpharmaceutical interventions on daily change in deaths, for 13 European countries, March–May 2020
| Model I | Model II | Model III | Model IV | |
|---|---|---|---|---|
| School closure | −2.9 | −3.3 | −2.5 | −22.1 |
| [−6.4, 0.62] | [−7.0, 0.5] | [−6.1, 1.1] | ||
| Workplace closure | −4.0 | −4.1 | −4.0 | |
| [−7.4, −0.5] | [−7.6, −0.5] | [−8.9, 0.9] | ||
| Restricting events | −5.9 | −2.2 | −13.0 | |
| [−9.8, −2.0] | ||||
| Restricting gathering size | 3.1 | [−7.6, 3.2] | ||
| [1.0, 5.2] | ||||
| Closure of public transport | 2.5 | −9.5 | ||
| [−1.7, 6.6] | [−27.4, −16.9] | |||
| Stay‐at‐home restrictions | −3.7 | [−20.0, −6.1] | ||
| [−11.8, 4.4] | ||||
| Restrictions on internal travel | −2.5 | [−16.9, −2.2] | ||
| [−7.3, 2.2] | ||||
| Restrictions on international travel | −5.4 | |||
| [−9.6, −1.1] | ||||
| Face mask requirements | −6.8 | −4.0 | −4.1 | |
| [−11.3, −2.2] | [−7.8, −0.3] | [−7.6, −0.62] | ||
| Continuous mobility | −7.5 | −8.8 | −10.0 | −8.5 |
| [−15.7, 0.62] | [−16.1, −1.4] | [−17.9, −2.1] | [−15.9, −1.1] | |
| Number of observations | 776 | 776 | 776 | 776 |
Note: 95% Confidence intervals are presented in square brackets. Specifications also included controls for t, t‐squared, the percentage of population older than 65, the population density, and number of acute care beds per 100,000 people, and the date when the 5‐day moving average of daily deaths is first equal to at least five. Standard errors are clustered at the country level. The unit of observation is a country‐day: 1 day of data for a specific country. All indicators of government restrictions are as defined in the Oxford tracker and are normalized across an interval [0,1] for the 13 countries. N lower than in Models I–III in Table 2 because the lagged mobility data are only available for Italy from the third day of the epidemic.
Significant at 5% level.
Significant at 1% level.
Significant at 0.1% level.