Literature DB >> 34165713

Pseudogenes as Competitive Endogenous RNAs: Testing miRNA Dependency.

Xiaonan Xu1, Florian A Karreth2.   

Abstract

Pseudogenes may function as competitive endogenous RNAs (ceRNAs), where they regulate the expression of genes by sequestering shared miRNAs. ceRNAs are becoming more extensively identified and studied, and demonstrating the dependence of their effects on miRNA sequestration is critical to establish them as ceRNAs. Here, we outline an experimental approach to assess the miRNA dependency of a candidate pseudogene ceRNA.

Keywords:  Pseudogene; ceRNA; miRNA

Year:  2021        PMID： 34165713     DOI： 10.1007/978-1-0716-1503-4_9

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  8 in total

Review 1.  PTEN ceRNA networks in human cancer.

Authors:  Laura Poliseno; Pier Paolo Pandolfi
Journal:  Methods       Date:  2015-01-30       Impact factor: 3.608

2.  Competitive endogenous RNAs cannot alter microRNA function in vivo.

Authors:  Jennifer A Broderick; Phillip D Zamore
Journal:  Mol Cell       Date:  2014-06-05       Impact factor: 17.970

3.  Assessing the ceRNA hypothesis with quantitative measurements of miRNA and target abundance.

Authors:  Rémy Denzler; Vikram Agarwal; Joanna Stefano; David P Bartel; Markus Stoffel
Journal:  Mol Cell       Date:  2014-05-01       Impact factor: 17.970

Review 4.  ceRNA cross-talk in cancer: when ce-bling rivalries go awry.

Authors:  Florian A Karreth; Pier Paolo Pandolfi
Journal:  Cancer Discov       Date:  2013-09-26       Impact factor: 39.397

5.  Endogenous miRNA and target concentrations determine susceptibility to potential ceRNA competition.

Authors:  Andrew D Bosson; Jesse R Zamudio; Phillip A Sharp
Journal:  Mol Cell       Date:  2014-10-23       Impact factor: 17.970

6.  A coding-independent function of gene and pseudogene mRNAs regulates tumour biology.

Authors:  Laura Poliseno; Leonardo Salmena; Jiangwen Zhang; Brett Carver; William J Haveman; Pier Paolo Pandolfi
Journal:  Nature       Date:  2010-06-24       Impact factor: 49.962

7.  Pseudogenes as competitive endogenous RNAs: target prediction and validation.

Authors:  Florian A Karreth; Ugo Ala; Paolo Provero; Pier Paolo Pandolfi
Journal:  Methods Mol Biol       Date:  2014

8.  Impact of MicroRNA Levels, Target-Site Complementarity, and Cooperativity on Competing Endogenous RNA-Regulated Gene Expression.

Authors:  Rémy Denzler; Sean E McGeary; Alexandra C Title; Vikram Agarwal; David P Bartel; Markus Stoffel
Journal:  Mol Cell       Date:  2016-10-27       Impact factor: 17.970
  8 in total
  2 in total

1.  ANXA2P2: A Potential Immunological and Prognostic Signature in Ovarian Serous Cystadenocarcinoma via Pan-Carcinoma Synthesis.

Authors:  Yanna Zhang; Ting Du; Xiancheng Chen
Journal:  Front Oncol       Date:  2022-02-08       Impact factor: 6.244

Review 2.  Novel Targets and Therapeutic Strategies to Protect Against Hepatic Ischemia Reperfusion Injury.

Authors:  Xin-Li Mao; Yue Cai; Ya-Hong Chen; Yi Wang; Xiu-Xiu Jiang; Li-Ping Ye; Shao-Wei Li
Journal:  Front Med (Lausanne)       Date:  2022-01-04
  2 in total

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