Literature DB >> 24823779

Pseudogenes as competitive endogenous RNAs: target prediction and validation.

Florian A Karreth1, Ugo Ala, Paolo Provero, Pier Paolo Pandolfi.   

Abstract

Pseudogenes may regulate expression of their parental genes as well as other protein-coding genes through various mechanisms. One such mechanism is the ability to act as competitive endogenous RNA (ceRNA) and participate in microRNA-mediated cross-regulation. Here, we outline how to predict the targets of pseudogene ceRNAs bioinformatically and how to validate them experimentally.

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Year:  2014        PMID: 24823779     DOI: 10.1007/978-1-4939-0835-6_13

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  9 in total

1.  Pseudogenes as Competitive Endogenous RNAs: Testing miRNA Dependency.

Authors:  Xiaonan Xu; Florian A Karreth
Journal:  Methods Mol Biol       Date:  2021

Review 2.  Oncocers: ceRNA-mediated cross-talk by sponging miRNAs in oncogenic pathways.

Authors:  Sercan Ergun; Serdar Oztuzcu
Journal:  Tumour Biol       Date:  2015-03-27

3.  Differentially-Expressed Pseudogenes in HIV-1 Infection.

Authors:  Aditi Gupta; C Titus Brown; Yong-Hui Zheng; Christoph Adami
Journal:  Viruses       Date:  2015-09-29       Impact factor: 5.048

4.  Does the linear Sry transcript function as a ceRNA for miR-138? The sense of antisense.

Authors:  Javier Tadeo Granados-Riveron; Guillermo Aquino-Jarquin
Journal:  F1000Res       Date:  2014-04-11

Review 5.  HMGA1-pseudogenes and cancer.

Authors:  Marco De Martino; Floriana Forzati; Claudio Arra; Alfredo Fusco; Francesco Esposito
Journal:  Oncotarget       Date:  2016-05-10

6.  miRNA regulation of Tip110 expression and self-renewal and differentiation of human CD34+ hematopoietic cells.

Authors:  Ying Liu; Xinxin Huang; Khalid A Timani; Hal E Broxmeyer; Johnny J He
Journal:  Oncotarget       Date:  2017-12-21

Review 7.  Competing Endogenous RNAs, Non-Coding RNAs and Diseases: An Intertwined Story.

Authors:  Ugo Ala
Journal:  Cells       Date:  2020-06-28       Impact factor: 6.600

8.  Comprehensive analysis of the long noncoding RNA-associated competitive endogenous RNA network in the osteogenic differentiation of periodontal ligament stem cells.

Authors:  Lingzhi Lai; Zhaodan Wang; Yihong Ge; Wei Qiu; Buling Wu; Fuchun Fang; Huiyong Xu; Zhao Chen
Journal:  BMC Genomics       Date:  2022-01-03       Impact factor: 3.969

Review 9.  Pseudogenes regulate parental gene expression via ceRNA network.

Authors:  Yang An; Kendra L Furber; Shaoping Ji
Journal:  J Cell Mol Med       Date:  2016-08-25       Impact factor: 5.310

  9 in total

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