PURPOSE: Flow Diverters (FD) have immensely extended the treatment of cerebral aneurysms in the past years. Complete aneurysm occlusion is a process that often takes a certain amount of time and is usually difficult to predict. Our aim was to investigate different syngo iFlow parameters in order to predict aneurysm occlusion. METHODS: Between 2014 and 2018 patients with unruptured cerebral aneurysms treated with a FD were reviewed. Aneurysm occlusion and complication rates have been assessed.In addition, various quantitative criteria were assessed using syngo iFlow before, after the intervention, and after short and long-term digital subtraction angiography (DSA). RESULTS: A total of 66 patients hosting 66 cerebral aneurysms were included in this study. 87.9% (n = 58) aneurysms in the anterior and 12.1% (n = 8) in the posterior circulation were treated. Adequate aneurysm occlusion at long-term follow-up (19.05 ± 15.1 months) was achieved in 90.9% (n = 60). Adequately occluded aneurysm revealed a significantly greater peak intensity delay (PI-D, p = 0.008) and intensity decrease ratio (ID-R, p < 0.001) compared to insufficiently occluded aneurysms. Increased intra-aneurysmal contrast agent intensity (>100%) after FD implantation resulted in an ID-R < 1, which was associated with aneurysm growth during follow-up DSA. Retreatment with another FD due to foreshortening and/or aneurysm growth was performed in 10.6% (n = 7). Overall morbidity and mortality rates were 1.5% (n = 1) and 0%. CONCLUSION: The applied syngo iFlow parameters were found to be useful in predicting adequate aneurysm occlusion and foresee aneurysm growth, which might indicate the implantation of another FD.
PURPOSE: Flow Diverters (FD) have immensely extended the treatment of cerebral aneurysms in the past years. Complete aneurysm occlusion is a process that often takes a certain amount of time and is usually difficult to predict. Our aim was to investigate different syngo iFlow parameters in order to predict aneurysm occlusion. METHODS: Between 2014 and 2018 patients with unruptured cerebral aneurysms treated with a FD were reviewed. Aneurysm occlusion and complication rates have been assessed.In addition, various quantitative criteria were assessed using syngo iFlow before, after the intervention, and after short and long-term digital subtraction angiography (DSA). RESULTS: A total of 66 patients hosting 66 cerebral aneurysms were included in this study. 87.9% (n = 58) aneurysms in the anterior and 12.1% (n = 8) in the posterior circulation were treated. Adequate aneurysm occlusion at long-term follow-up (19.05 ± 15.1 months) was achieved in 90.9% (n = 60). Adequately occluded aneurysm revealed a significantly greater peak intensity delay (PI-D, p = 0.008) and intensity decrease ratio (ID-R, p < 0.001) compared to insufficiently occluded aneurysms. Increased intra-aneurysmal contrast agent intensity (>100%) after FD implantation resulted in an ID-R < 1, which was associated with aneurysm growth during follow-up DSA. Retreatment with another FD due to foreshortening and/or aneurysm growth was performed in 10.6% (n = 7). Overall morbidity and mortality rates were 1.5% (n = 1) and 0%. CONCLUSION: The applied syngo iFlow parameters were found to be useful in predicting adequate aneurysm occlusion and foresee aneurysm growth, which might indicate the implantation of another FD.
Authors: L Ian Taylor; James C Dickerson; Robert J Dambrino; M Yashar S Kalani; Philipp Taussky; Chad W Washington; Min S Park Journal: Neurosurg Focus Date: 2017-06 Impact factor: 4.047
Authors: Christoph J Griessenauer; Alejandro Enriquez-Marulanda; Sissi Xiang; Tao Hong; Hongqi Zhang; Philipp Taussky; Ramesh Grandhi; Muhammad Waqas; Vincent M Tutino; Adnan H Siddiqui; Elad I Levy; Christopher S Ogilvy; Ajith J Thomas; Christian Ulfert; Markus A Möhlenbruch; Leonardo Renieri; Nicola Limbucci; Carmen Parra-Fariñas; Jan-Karl Burkhardt; Peter Kan; Lorenzo Rinaldo; Giuseppe Lanzino; Waleed Brinjikji; Julian Spears; Erasmia Müller-Thies-Broussalis; Monika Killer-Oberpfalzer; Civan Islak; Naci Kocer; Michael Sonnberger; Tobias Engelhorn; Mandeep Ghuman; Victor Xd Yang; Arsalaan Salehani; Mark R Harrigan; Ivan Radovanovic; Vitor M Pereira; Timo Krings; Charles C Matouk; Karen Chen; Mohammad Ali Aziz-Sultan; Mohammad Ghorbani; Clemens M Schirmer; Oded Goren; Shamsher S Dalal; Matthew J Koch; Christopher J Stapleton; Aman B Patel; Thomas Finkenzeller; Markus Holtmannspötter; Jan Hendrik Buhk; Paul Michael Foreman; Marshall Cress; Robert Hirschl; Wolfgang Reith; Andreas Simgen; Hendrik Janssen; Thomas R Marotta; Adam A Dmytriw Journal: J Neurointerv Surg Date: 2020-07-01 Impact factor: 5.836
Authors: P Gölitz; T Struffert; H Lücking; J Rösch; F Knossalla; O Ganslandt; Y Deuerling-Zheng; A Doerfler Journal: Clin Neuroradiol Date: 2012-12-14 Impact factor: 3.649
Authors: Satoshi Tateshima; Jesse G Jones; Fernando Mayor Basto; Fernando Vinuela; Gary R Duckwiler Journal: J Neurointerv Surg Date: 2014-05-28 Impact factor: 5.836