Ramachandran S Vasan1,2,3, Elman Martin Urbina4, Ling Jin4, Vanessa Xanthakis5,6,7. 1. Boston University's and National Heart, Lung, and Blood Institute's Framingham Heart Study, 73 Mount Wayte Avenue, Suite 2, Framingham, MA, 01702, USA. vasan@bu.edu. 2. Sections of Preventive Medicine and Epidemiology, and Cardiovascular Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA. vasan@bu.edu. 3. Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA. vasan@bu.edu. 4. Division of Internal Medicine, MetroWest Medical Center, Framingham, MA, USA. 5. Boston University's and National Heart, Lung, and Blood Institute's Framingham Heart Study, 73 Mount Wayte Avenue, Suite 2, Framingham, MA, 01702, USA. 6. Sections of Preventive Medicine and Epidemiology, and Cardiovascular Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA. 7. Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Abstract
PURPOSE OF REVIEW: Echocardiography is a noninvasive tool of choice for evaluating cardiac structure and function in numerous cardiac conditions ranging from congenital heart disease, myocardial diseases, coronary artery disease (CAD), valvulopathies, arrhythmias, and pericardial disorders. We review the prognostic significance of echocardiographic indices of cardiac remodeling in the general population. RECENT FINDINGS: Recent meta-analyses have confirmed the prognostic significance of echocardiographic measurements (left ventricular mass/hypertrophy, systolic and diastolic dysfunction, left atrial dimensions and function, and strain rate measures) in asymptomatic people in the community for adverse clinical outcomes including CAD, stroke, heart failure, atrial fibrillation, sudden death, and all-cause mortality. The clinical utility of screening echocardiography has been examined comprehensively in hypertensive patients, where it is challenged by measurement variability. Echocardiographic measures predict cardiovascular disease outcomes consistently in multiple community-based epidemiological studies. However, the clinical utility of screening asymptomatic individuals with echocardiography in population-based settings is limited.
PURPOSE OF REVIEW: Echocardiography is a noninvasive tool of choice for evaluating cardiac structure and function in numerous cardiac conditions ranging from congenital heart disease, myocardial diseases, coronary artery disease (CAD), valvulopathies, arrhythmias, and pericardial disorders. We review the prognostic significance of echocardiographic indices of cardiac remodeling in the general population. RECENT FINDINGS: Recent meta-analyses have confirmed the prognostic significance of echocardiographic measurements (left ventricular mass/hypertrophy, systolic and diastolic dysfunction, left atrial dimensions and function, and strain rate measures) in asymptomatic people in the community for adverse clinical outcomes including CAD, stroke, heart failure, atrial fibrillation, sudden death, and all-cause mortality. The clinical utility of screening echocardiography has been examined comprehensively in hypertensivepatients, where it is challenged by measurement variability. Echocardiographic measures predict cardiovascular disease outcomes consistently in multiple community-based epidemiological studies. However, the clinical utility of screening asymptomatic individuals with echocardiography in population-based settings is limited.
Authors: John S Gottdiener; James Bednarz; Richard Devereux; Julius Gardin; Allan Klein; Warren J Manning; Annitta Morehead; Dalane Kitzman; Jae Oh; Miguel Quinones; Nelson B Schiller; James H Stein; Neil J Weissman Journal: J Am Soc Echocardiogr Date: 2004-10 Impact factor: 5.251
Authors: Pamela S Douglas; Bijoy Khandheria; Raymond F Stainback; Neil J Weissman; Ralph G Brindis; Manesh R Patel; Bijoy Khandheria; Joseph S Alpert; David Fitzgerald; Paul Heidenreich; Edward T Martin; Joseph V Messer; Alan B Miller; Michael H Picard; Paolo Raggi; Kim D Reed; John S Rumsfeld; Anthony E Steimle; Russ Tonkovic; Krishnaswami Vijayaraghavan; Neil J Weissman; Susan Bok Yeon; Ralph G Brindis; Pamela S Douglas; Robert C Hendel; Manesh R Patel; Eric Peterson; Michael J Wolk; Joseph M Allen Journal: J Am Coll Cardiol Date: 2007-07-10 Impact factor: 24.094
Authors: Thomas R Porter; Sasha K Shillcutt; Mark S Adams; Georges Desjardins; Kathryn E Glas; Joan J Olson; Richard W Troughton Journal: J Am Soc Echocardiogr Date: 2015-01 Impact factor: 5.251
Authors: Kofo O Ogunyankin; Kiang Liu; Donald M Lloyd-Jones; Laura A Colangelo; Julius M Gardin Journal: Echocardiography Date: 2011-01-07 Impact factor: 1.724
Authors: Susan Cheng; Martin G Larson; Elizabeth L McCabe; Ewa Osypiuk; Birgitta T Lehman; Plamen Stanchev; Jayashri Aragam; Emelia J Benjamin; Scott D Solomon; Ramachandran S Vasan Journal: Circ Cardiovasc Imaging Date: 2013-08-05 Impact factor: 7.792
Authors: Ramachandran S Vasan; Nicole L Glazer; Janine F Felix; Wolfgang Lieb; Philipp S Wild; Stephan B Felix; Norbert Watzinger; Martin G Larson; Nicholas L Smith; Abbas Dehghan; Anika Grosshennig; Arne Schillert; Alexander Teumer; Reinhold Schmidt; Sekar Kathiresan; Thomas Lumley; Yurii S Aulchenko; Inke R König; Tanja Zeller; Georg Homuth; Maksim Struchalin; Jayashri Aragam; Joshua C Bis; Fernando Rivadeneira; Jeanette Erdmann; Renate B Schnabel; Marcus Dörr; Robert Zweiker; Lars Lind; Richard J Rodeheffer; Karin Halina Greiser; Daniel Levy; Talin Haritunians; Jaap W Deckers; Jan Stritzke; Karl J Lackner; Uwe Völker; Erik Ingelsson; Iftikhar Kullo; Johannes Haerting; Christopher J O'Donnell; Susan R Heckbert; Bruno H Stricker; Andreas Ziegler; Thorsten Reffelmann; Margaret M Redfield; Karl Werdan; Gary F Mitchell; Kenneth Rice; Donna K Arnett; Albert Hofman; John S Gottdiener; Andre G Uitterlinden; Thomas Meitinger; Maria Blettner; Nele Friedrich; Thomas J Wang; Bruce M Psaty; Cornelia M van Duijn; H-Erich Wichmann; Thomas F Munzel; Heyo K Kroemer; Emelia J Benjamin; Jerome I Rotter; Jacqueline C Witteman; Heribert Schunkert; Helena Schmidt; Henry Völzke; Stefan Blankenberg Journal: JAMA Date: 2009-07-08 Impact factor: 56.272
Authors: J M Gardin; D Siscovick; H Anton-Culver; J C Lynch; V E Smith; H S Klopfenstein; W J Bommer; L Fried; D O'Leary; T A Manolio Journal: Circulation Date: 1995-03-15 Impact factor: 29.690