Literature DB >> 34080249

Dysphagia profiles after primary transoral robotic surgery or radiation for oropharyngeal cancer: A registry analysis.

Carly E A Barbon1, Christopher M K L Yao1, Clare P Alvarez1, Ryan P Goepfert1, Clifton D Fuller2, Stephen Y Lai1,2, Neil D Gross1, Katherine A Hutcheson1,2.   

Abstract

OBJECTIVE: To describe the physiologic swallowing impairments (MBSImP™©) associated with safety/efficiency impairments (DIGESTsafety /DIGESTefficiency grades) at 3-6 months after transoral robotic surgery (TORS) or radiation therapy (RT). STUDY
DESIGN: Secondary analysis of registry data.
SETTING: Single, academic institution.
METHODS: Two hundred and fifty-seven patients with HPV+ oropharynx cancer were stratified by primary treatment (75 TORS, 182 RT). Modified barium swallow studies were analyzed at baseline and 3-6 months using MBSImP scores and DIGESTsafety /DIGESTefficiency grades. DIGESTsafety /DIGESTefficiency grades and MBSImP were compared groupwise and associations between DIGESTsafety /DIGESTefficiency grades and MBSImP were explored by ordinal logistic regression. Exploratory analyses were stratified by multimodality treatment.
RESULTS: Neither DIGESTsafety /DIGESTefficiency differed significantly between groups at baseline or 3-6 months. Laryngeal vestibule closure was impaired more frequently in the RT group (RT: 41% vs. TORS: 27%; p = 0.02) while the TORS group had significantly more pharyngeal contraction impairment (63%; p < 0.001) compared to RT at 3-6 months.
CONCLUSION: The results suggest a focal injury associated with DIGESTsafety /DIGESTefficiency post-TORS in contrast to a low-level diffuse physiologic impairment associated with post-RT dysphagia.
© 2021 Wiley Periodicals LLC.

Entities:  

Keywords:  dysphagia; head and neck cancer; radiation; surgery

Mesh：

Year:  2021        PMID： 34080249      PMCID： PMC8450940          DOI： 10.1002/hed.26768

Source DB:  PubMed          Journal:  Head Neck        ISSN： 1043-3074            Impact factor:   3.821


  28 in total

1.  Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support.

Authors:  Paul A Harris; Robert Taylor; Robert Thielke; Jonathon Payne; Nathaniel Gonzalez; Jose G Conde
Journal:  J Biomed Inform       Date:  2008-09-30       Impact factor: 6.317

2.  Relationship between fluoroscopic and manometric measures of pharyngeal constriction: the pharyngeal constriction ratio.

Authors:  Rebecca Leonard; Peter C Belafsky; Catherine J Rees
Journal:  Ann Otol Rhinol Laryngol       Date:  2006-12       Impact factor: 1.547

3.  Patterns of disease recurrence following treatment of oropharyngeal cancer with intensity modulated radiation therapy.

Authors:  Adam S Garden; Lei Dong; William H Morrison; Erich M Stugis; Bonnie S Glisson; Steven J Frank; Beth M Beadle; Gary B Gunn; David L Schwartz; Merill S Kies; Randal S Weber; K Kian Ang; David I Rosenthal
Journal:  Int J Radiat Oncol Biol Phys       Date:  2012-09-11       Impact factor: 7.038

4.  The REDCap consortium: Building an international community of software platform partners.

Authors:  Paul A Harris; Robert Taylor; Brenda L Minor; Veida Elliott; Michelle Fernandez; Lindsay O'Neal; Laura McLeod; Giovanni Delacqua; Francesco Delacqua; Jacqueline Kirby; Stephany N Duda
Journal:  J Biomed Inform       Date:  2019-05-09       Impact factor: 6.317

Review 5.  Physiological changes to the swallowing mechanism following (chemo)radiotherapy for head and neck cancer: a systematic review.

Authors:  Laurelie R Wall; Elizabeth C Ward; Bena Cartmill; Anne J Hill
Journal:  Dysphagia       Date:  2013-12       Impact factor: 3.438

6.  Respiratory-swallow phase patterns and their relationship to swallowing impairment in patients treated for oropharyngeal cancer.

Authors:  Martin B Brodsky; David H McFarland; Thomas S Dozier; Julie Blair; Christopher Ayers; Yvonne Michel; M Boyd Gillespie; Terry A Day; Bonnie Martin-Harris
Journal:  Head Neck       Date:  2010-04       Impact factor: 3.147

7.  MBS measurement tool for swallow impairment--MBSImp: establishing a standard.

Authors:  Bonnie Martin-Harris; Martin B Brodsky; Yvonne Michel; Donald O Castell; Melanie Schleicher; John Sandidge; Rebekah Maxwell; Julie Blair
Journal:  Dysphagia       Date:  2008-10-15       Impact factor: 3.438

8.  Decreased gastrostomy tube incidence and weight loss after transoral robotic surgery for low- to intermediate-risk oropharyngeal squamous cell carcinoma.

Authors:  Harold Heah; Ryan P Goepfert; Katherine A Hutcheson; Adam S Garden; G Brandon Gunn; Clifton D Fuller; Jan S Lewin; Michael E Kupferman; F Christopher Holsinger; Amy C Hessel; Neil D Gross
Journal:  Head Neck       Date:  2018-08-13       Impact factor: 3.147

9.  Radiotherapy dose-volume parameters predict videofluoroscopy-detected dysphagia per DIGEST after IMRT for oropharyngeal cancer: Results of a prospective registry.

Authors:  Mona Kamal; Abdallah S R Mohamed; Stefania Volpe; Jhankruti Zaveri; Martha Portwood Barrow; G Brandon Gunn; Stephen Y Lai; Renata Ferrarotto; Jan S Lewin; David I Rosenthal; Amit Jethanandani; Mohamed Ahmed Mohamed Meheissen; Samuel L Mulder; Carlos E Cardenas; Clifton D Fuller; Katherine A Hutcheson
Journal:  Radiother Oncol       Date:  2018-06-28       Impact factor: 6.280

10.  Reference Values for Healthy Swallowing Across the Range From Thin to Extremely Thick Liquids.

Authors:  Catriona M Steele; Melanie Peladeau-Pigeon; Carly A E Barbon; Brittany T Guida; Ashwini M Namasivayam-MacDonald; Weslania V Nascimento; Sana Smaoui; Melanie S Tapson; Teresa J Valenzano; Ashley A Waito; Talia S Wolkin
Journal:  J Speech Lang Hear Res       Date:  2019-05-21       Impact factor: 2.297
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.