BACKGROUND: Unstable respiratory-swallowing coordination has been associated with disorders and disease. The goals of this study were (1) to describe respiratory-swallow patterns in patients with dysphagia consequent to treatments for cancers of the oropharynx and (2) to determine the association between respiratory-swallow patterns, airway invasion, and overall severity of swallowing impairment. METHODS: This prospective, cross-sectional design compared respiratory-swallow patterns in 20 patients treated for oropharyngeal cancer and 20 healthy, age-matched control participants. Nasal airflow direction was synchronously recorded with videofluoroscopic imaging in participants who swallowed 5-mL thin liquid barium boluses. RESULTS: Respiratory-swallow patterns differed between groups. Most control participants initiated and completed swallowing bracketed by expiratory airflow. Swallowing in patients often interrupted inspiratory flow and was associated with penetration or aspiration of the bolus. CONCLUSIONS: We suggest nonexpiratory bracketed respiratory-swallowing phase patterns in patients with oropharyngeal cancer may place patients at greater risk of airway penetration or aspiration during swallowing.
BACKGROUND: Unstable respiratory-swallowing coordination has been associated with disorders and disease. The goals of this study were (1) to describe respiratory-swallow patterns in patients with dysphagia consequent to treatments for cancers of the oropharynx and (2) to determine the association between respiratory-swallow patterns, airway invasion, and overall severity of swallowing impairment. METHODS: This prospective, cross-sectional design compared respiratory-swallow patterns in 20 patients treated for oropharyngeal cancer and 20 healthy, age-matched control participants. Nasal airflow direction was synchronously recorded with videofluoroscopic imaging in participants who swallowed 5-mL thin liquid barium boluses. RESULTS: Respiratory-swallow patterns differed between groups. Most control participants initiated and completed swallowing bracketed by expiratory airflow. Swallowing in patients often interrupted inspiratory flow and was associated with penetration or aspiration of the bolus. CONCLUSIONS: We suggest nonexpiratory bracketed respiratory-swallowing phase patterns in patients with oropharyngeal cancer may place patients at greater risk of airway penetration or aspiration during swallowing.
Authors: Gillian M Nixon; Isabelle Charbonneau; Andrea S Kermack; Robert T Brouillette; David H McFarland Journal: Respir Physiol Neurobiol Date: 2007-08-26 Impact factor: 1.931
Authors: Nam P Nguyen; Candace C Moltz; Cheryl Frank; Ulf Karlsson; Phuc D Nguyen; Paul Vos; Herbert J Smith; Suresh Dutta; Ly M Nguyen; Claire Lemanski; Wayne Chan; Sabah Sallah Journal: Eur J Radiol Date: 2006-05-09 Impact factor: 3.528
Authors: Thomas S Dozier; Martin B Brodsky; Yvonne Michel; Bobby C Walters; Bonnie Martin-Harris Journal: Laryngoscope Date: 2006-08 Impact factor: 3.325
Authors: Vincent Jobin; Victoria Champagne; Josée Beauregard; Isabelle Charbonneau; David H McFarland; R John Kimoff Journal: J Appl Physiol (1985) Date: 2006-12-21
Authors: Cathy Lazarus; Jeri A Logemann; Barbara Roa Pauloski; Alfred W Rademaker; Irene B Helenowski; Edward F Vonesh; Ellen Maccracken; Bharat B Mittal; Everett E Vokes; Daniel J Haraf Journal: Head Neck Date: 2007-07 Impact factor: 3.147
Authors: Nam P Nguyen; Herbert J Smith; Suresh Dutta; Alan Alfieri; Debra North; Phuc D Nguyen; Howard Lee; Tomas Martinez; Claire Lemanski; Adir Ludin; Ly M Nguyen; Sabah Sallah Journal: Anticancer Res Date: 2007 May-Jun Impact factor: 2.480
Authors: Felix Y Feng; Hyungjin M Kim; Teresa H Lyden; Marc J Haxer; Mary Feng; Frank P Worden; Douglas B Chepeha; Avraham Eisbruch Journal: Int J Radiat Oncol Biol Phys Date: 2007-06-07 Impact factor: 7.038
Authors: Alyssa Huff; Trevor A Day; Mason English; Mitchell D Reed; Shaelynn Zouboules; Gurkarn Saran; Jack K Leacy; Carli Mann; Joel D B Peltonen; Ken D O'Halloran; Mingma T Sherpa; Teresa Pitts Journal: Respir Physiol Neurobiol Date: 2018-06-18 Impact factor: 1.931
Authors: D H McFarland; B Martin-Harris; A-J Fortin; K Humphries; E Hill; K Armeson Journal: Respir Physiol Neurobiol Date: 2016-09-06 Impact factor: 1.931
Authors: Martin B Brodsky; David H McFarland; Yvonne Michel; Suzanne B Orr; Bonnie Martin-Harris Journal: Dysphagia Date: 2011-07-07 Impact factor: 3.438
Authors: D L Oliveira; E A M Moreira; M B de Freitas; J de A Gonçalves; A M Furkim; P Clavé Journal: J Nutr Health Aging Date: 2017 Impact factor: 4.075
Authors: Bonnie Martin-Harris; David McFarland; Elizabeth G Hill; Charlton B Strange; Kendrea L Focht; Zhuang Wan; Julie Blair; Katlyn McGrattan Journal: Arch Phys Med Rehabil Date: 2014-12-11 Impact factor: 3.966