Marcel F Kunrath1,2, Saurabh Gupta3,4, Felice Lorusso5, Antonio Scarano3,5, Sammy Noumbissi3,5. 1. Dentistry Department, School of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul (PUCRS), P.O. Box 6681, Porto Alegre 90619-900, RS, Brazil. 2. Materials and Nanoscience Laboratory, Pontifical Catholic University of Rio Grande do Sul (PUCRS), P.O. Box 6681, Porto Alegre 90619-900, RS, Brazil. 3. Zirconia Implant Research Group (Z.I.R.G), International Academy of Ceramic Implantology, Silver Spring, MD 20901, USA. 4. Master Dental Science, Universitat Jaume I, 12071 Castellón de la Plana, Spain. 5. Department of Innovative Technologies in Medicine & Dentistry, University of Chieti-Pescara, Via dei Vestini, 31-66100 Chieti, CH, Italy.
Abstract
BACKGROUND: Dental components manufactured with zirconia (ZrO2) represent a significant percentage of the implant prosthetic market in dentistry. However, during the last few years, we have observed robust clinical and pre-clinical scientific investigations on zirconia both as a prosthetic and an implantable material. At the same time, we have witnessed consistent technical and manufacturing updates with regards to the applications of zirconia which appear to gradually clarify points which until recently were not well understood. METHODS: This critical review evaluated the "state of the art" in relation to applications of this biomaterial in dental components and its interactions with oral tissues. RESULTS: The physico-chemical and structural properties as well as the current surface treatment methodologies for ZrO2 were explored. A critical investigation of the cellular response to this biomaterial was completed and the clinical implications discussed. Finally, surface treatments of ZrO2 demonstrate that excellent osseointegration is possible and provide encouraging prospects for rapid bone adhesion. Furthermore, sophisticated surface treatment techniques and technologies are providing impressive oral soft tissue cell responses thus leading to superior biological seal. CONCLUSIONS: Dental devices manufactured from ZrO2 are structurally and chemically stable with biocompatibility levels allowing for safe and long-term function in the oral environment.
BACKGROUND: Dental components manufactured with zirconia (ZrO2) represent a significant percentage of the implant prosthetic market in dentistry. However, during the last few years, we have observed robust clinical and pre-clinical scientific investigations on zirconia both as a prosthetic and an implantable material. At the same time, we have witnessed consistent technical and manufacturing updates with regards to the applications of zirconia which appear to gradually clarify points which until recently were not well understood. METHODS: This critical review evaluated the "state of the art" in relation to applications of this biomaterial in dental components and its interactions with oral tissues. RESULTS: The physico-chemical and structural properties as well as the current surface treatment methodologies for ZrO2 were explored. A critical investigation of the cellular response to this biomaterial was completed and the clinical implications discussed. Finally, surface treatments of ZrO2 demonstrate that excellent osseointegration is possible and provide encouraging prospects for rapid bone adhesion. Furthermore, sophisticated surface treatment techniques and technologies are providing impressive oral soft tissue cell responses thus leading to superior biological seal. CONCLUSIONS: Dental devices manufactured from ZrO2 are structurally and chemically stable with biocompatibility levels allowing for safe and long-term function in the oral environment.
Authors: Antonio Liñares; Leticia Grize; Fernando Muñoz; Benjamin Evans Pippenger; Michel Dard; Olivier Domken; Juan Blanco-Carrión Journal: J Clin Periodontol Date: 2016-05-02 Impact factor: 8.728
Authors: Marcel F Kunrath; Fernando M Diz; Ricardo Magini; María E Galárraga-Vinueza Journal: Adv Colloid Interface Sci Date: 2020-09-08 Impact factor: 12.984
Authors: J H Dubruille; E Viguier; G Le Naour; M T Dubruille; M Auriol; Y Le Charpentier Journal: Int J Oral Maxillofac Implants Date: 1999 Mar-Apr Impact factor: 2.804
Authors: Marcel F Kunrath; Marina S G Monteiro; Saurabh Gupta; Roberto Hubler; Sílvia D de Oliveira Journal: Arch Oral Biol Date: 2020-06-22 Impact factor: 2.633