Literature DB >> 34046221

Time motion study to evaluate the impact of flattening filter free beam on overall treatment time for frameless intracranial radiosurgery using Varian TrueBeam® linear accelerator.

Gopinath Mamballikalam1,2, S Senthilkumar3, C O Clinto2, P M Ahamed Basith2, R C Jaon Bos2, Tems Thomas2.   

Abstract

BACKGROUND: The aim was to study the impact of the flattening filter free (FFF) beam on overall treatment time for frameless intracranial radiosurgery using TrueBeam® LINAC.The development of frameless stereotactic radiosurgery (SRS) is possible due to the incorporation of image guidance in the delivery of treatment. It is important to analyze the cost and benefits of FFF beams for treating SRS by understanding the impact of FFF beams in reducing the treatment time.
MATERIALS AND METHODS: Dynamic conformal arc (DCA ) and volumetric arc therapy (VMAT) plans were generated using 6 MV with a flattening filter (FF) and FFF beams. Overall treatment time was divided into beam on time (BOT) and beam off time (BFT). Percentage beam on time reduction (PBOTR) and Percentage total time reduction (PTTR) factors were defined for the comparison.
RESULTS: BOT reduction was observed to be significant for higher dose per fraction but subjected to the treatment technique and modulation differences. PBOTR values are much higher than PTTR values. The 39.9% of PBOTR resulted in only 8% PTTR for DCA and 65.3% resulted in 15.9% PTTR for VMAT.
CONCLUSION: Major BFT was utilized for imaging and verification. FFF beam significantly reduced the beam on time and was found to be most effective if the fractional dose was as high as that for SRS. Newly defined PBOTR and PTTR factors are very useful indicators to evaluate the efficacy of FFF beams in terms of time reduction.
© 2021 Greater Poland Cancer Centre.

Entities:  

Keywords:  flattening filter free; frameless SRS; stereotactic radiosurgery; time motion study; treatment time

Year:  2021        PMID: 34046221      PMCID: PMC8149126          DOI: 10.5603/RPOR.a2021.0018

Source DB:  PubMed          Journal:  Rep Pract Oncol Radiother        ISSN: 1507-1367


  21 in total

1.  Flattening-filter-free intensity modulated breath-hold image-guided SABR (Stereotactic ABlative Radiotherapy) can be applied in a 15-min treatment slot.

Authors:  Judit Boda-Heggemann; Sabine Mai; Jens Fleckenstein; Kerstin Siebenlist; Anna Simeonova; Michael Ehmann; Volker Steil; Frederik Wenz; Frank Lohr; Florian Stieler
Journal:  Radiother Oncol       Date:  2013-10-12       Impact factor: 6.280

2.  Cone beam CT image guidance for intracranial stereotactic treatments: comparison with a frame guided set-up.

Authors:  Laura Masi; Franco Casamassima; Caterina Polli; Claudia Menichelli; Ivano Bonucci; Carlo Cavedon
Journal:  Int J Radiat Oncol Biol Phys       Date:  2008-07-01       Impact factor: 7.038

3.  The effect of MLC speed and acceleration on the plan delivery accuracy of VMAT.

Authors:  J M Park; H-G Wu; J H Kim; J N K Carlson; K Kim
Journal:  Br J Radiol       Date:  2015-03-03       Impact factor: 3.039

4.  A system for stereotactic radiosurgery with a linear accelerator.

Authors:  W Lutz; K R Winston; N Maleki
Journal:  Int J Radiat Oncol Biol Phys       Date:  1988-02       Impact factor: 7.038

5.  Intracranial stereotactic positioning systems: Report of the American Association of Physicists in Medicine Radiation Therapy Committee Task Group No. 68.

Authors:  A W Lightstone; Stanley H Benedict; Frank J Bova; Timothy D Solberg; Robin L Stern
Journal:  Med Phys       Date:  2005-07       Impact factor: 4.071

6.  Intensity modulated radiosurgery of brain metastases with flattening filter-free beams.

Authors:  Florian Stieler; Jens Fleckenstein; Anna Simeonova; Frederik Wenz; Frank Lohr
Journal:  Radiother Oncol       Date:  2013-11-11       Impact factor: 6.280

7.  Feasibility and early clinical assessment of flattening filter free (FFF) based stereotactic body radiotherapy (SBRT) treatments.

Authors:  Marta Scorsetti; Filippo Alongi; Simona Castiglioni; Alessandro Clivio; Antonella Fogliata; Francesca Lobefalo; Pietro Mancosu; Pierina Navarria; Valentina Palumbo; Chiara Pellegrini; Sara Pentimalli; Giacomo Reggiori; Anna M Ascolese; Antonella Roggio; Stefano Arcangeli; Angelo Tozzi; Eugenio Vanetti; Luca Cozzi
Journal:  Radiat Oncol       Date:  2011-09-12       Impact factor: 3.481

8.  Flattening filter-free linac improves treatment delivery efficiency in stereotactic body radiation therapy.

Authors:  Brendan M Prendergast; John B Fiveash; Richard A Popple; Grant M Clark; Evan M Thomas; Douglas J Minnich; Rojymon Jacob; Sharon A Spencer; James A Bonner; Michael C Dobelbower
Journal:  J Appl Clin Med Phys       Date:  2013-05-06       Impact factor: 2.102

9.  To frame or not to frame? Cone-beam CT-based analysis of head immobilization devices specific to linac-based stereotactic radiosurgery and radiotherapy.

Authors:  Steven Babic; Young Lee; Mark Ruschin; Fiona Lochray; Alex Lightstone; Eshetu Atenafu; Nic Phan; Todd Mainprize; May Tsao; Hany Soliman; Arjun Sahgal
Journal:  J Appl Clin Med Phys       Date:  2018-01-24       Impact factor: 2.102

10.  Evaluation of stability of stereotactic space defined by cone-beam CT for the Leksell Gamma Knife Icon.

Authors:  Ismail AlDahlawi; Dheerendra Prasad; Matthew B Podgorsak
Journal:  J Appl Clin Med Phys       Date:  2017-04-17       Impact factor: 2.102

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