Literature DB >> 3402603

NMR-invisible lactate in blood plasma.

J D Bell1, J C Brown, G Kubal, P J Sadler.   

Abstract

Resonances for lactate are broadened in 500 MHz 1H NMR spectra of human blood plasma and only about one-third is visible in Hahn spin-echo spectra. Similar effects are observed for some other carboxylate anions. Lactate added to the high-Mr fraction of plasma can give rise to peaks which are too broad to observe in either single-pulse or spin-echo spectra. Addition of agents such as NH4Cl of SDS dramatically increases the intensities of lactate peaks. Some glycoproteins appear to broaden lactate resonances.

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Year:  1988        PMID: 3402603     DOI: 10.1016/0014-5793(88)81238-9

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  14 in total

1.  The application of micro-coil NMR probe technology to metabolomics of urine and serum.

Authors:  John H Grimes; Thomas M O'Connell
Journal:  J Biomol NMR       Date:  2011-03-06       Impact factor: 2.835

2.  Citrate NMR peak irreproducibility in blood samples after reacquisition of spectra.

Authors:  Munsoor A Hanifa; Raluca G Maltesen; Bodil S Rasmussen; Katrine B Buggeskov; Hanne B Ravn; Martin Skott; Søren Nielsen; Jørgen Frøkiær; Troels Ring; Reinhard Wimmer
Journal:  Metabolomics       Date:  2019-12-19       Impact factor: 4.290

3.  Massive glutamine cyclization to pyroglutamic acid in human serum discovered using NMR spectroscopy.

Authors:  G A Nagana Gowda; Yashas N Gowda; Daniel Raftery
Journal:  Anal Chem       Date:  2015-03-17       Impact factor: 6.986

4.  NMR-Guided Mass Spectrometry for Absolute Quantitation of Human Blood Metabolites.

Authors:  G A Nagana Gowda; Danijel Djukovic; Lisa Fan Bettcher; Haiwei Gu; Daniel Raftery
Journal:  Anal Chem       Date:  2018-01-09       Impact factor: 6.986

Review 5.  A guide to the metabolic pathways and function of metabolites observed in human brain 1H magnetic resonance spectra.

Authors:  Caroline D Rae
Journal:  Neurochem Res       Date:  2013-11-21       Impact factor: 3.996

6.  Lactate detection in inducible and orthotopic Her2/neu mammary gland tumours in mouse models.

Authors:  S Magnitsky; G K Belka; C Sterner; S Pickup; L A Chodosh; J D Glickson
Journal:  NMR Biomed       Date:  2012-07-05       Impact factor: 4.044

7.  In vivo and ex vivo magnetic resonance spectroscopy of the infarct and the subventricular zone in experimental stroke.

Authors:  Elena Jiménez-Xarrié; Myriam Davila; Sara Gil-Perotín; Andrés Jurado-Rodríguez; Ana Paula Candiota; Raquel Delgado-Mederos; Silvia Lope-Piedrafita; José Manuel García-Verdugo; Carles Arús; Joan Martí-Fàbregas
Journal:  J Cereb Blood Flow Metab       Date:  2015-01-21       Impact factor: 6.200

8.  Characterization of a specific signal from human pancreatic tumors heterotransplanted into nude mice. Study by high resolution 1H NMR and HPLC.

Authors:  C Chemin-Thomas; J Esclassan; C Palevody; E Hollande
Journal:  Int J Pancreatol       Date:  1993-06

9.  High-resolution proton nuclear magnetic resonance studies of urine from asphyxiated newborn infants.

Authors:  S Ma; L I Shieh; C C Huang
Journal:  Appl Biochem Biotechnol       Date:  1995-04       Impact factor: 2.926

10.  NMR Spectroscopy-Based Metabolic Profiling of Biospecimens.

Authors:  Arjun Sengupta; Aalim M Weljie
Journal:  Curr Protoc Protein Sci       Date:  2019-12
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