Literature DB >> 34018204

Transporting experimental results with entropy balancing.

Kevin P Josey1, Seth A Berkowitz2, Debashis Ghosh1, Sridharan Raghavan3,4.   

Abstract

We show how entropy balancing can be used for transporting experimental treatment effects from a trial population onto a target population. This method is doubly robust in the sense that if either the outcome model or the probability of trial participation is correctly specified, then the estimate of the target population average treatment effect is consistent. Furthermore, we only require the sample moments of the effect modifiers drawn from the target population to consistently estimate the target population average treatment effect. We compared the finite-sample performance of entropy balancing with several alternative methods for transporting treatment effects between populations. Entropy balancing techniques are efficient and robust to violations of model misspecification. We also examine the results of our proposed method in an applied analysis of the Action to Control Cardiovascular Risk in Diabetes Blood Pressure trial transported to a sample of US adults with diabetes taken from the National Health and Nutrition Examination Survey cohort.
© 2021 John Wiley & Sons Ltd.

Entities:  

Keywords:  calibration; causal inference; effect modification; generalizability

Mesh:

Year:  2021        PMID: 34018204      PMCID: PMC8487904          DOI: 10.1002/sim.9031

Source DB:  PubMed          Journal:  Stat Med        ISSN: 0277-6715            Impact factor:   2.497


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