Literature DB >> 34015676

Memory is key in capturing COVID-19 epidemiological dynamics.

Mircea T Sofonea1, Bastien Reyné2, Baptiste Elie2, Ramsès Djidjou-Demasse2, Christian Selinger2, Yannis Michalakis2, Samuel Alizon2.   

Abstract

SARS-CoV-2 virus has spread over the world rapidly creating one of the largest pandemics ever. The absence of immunity, presymptomatic transmission, and the relatively high level of virulence of the COVID-19 infection led to a massive flow of patients in intensive care units (ICU). This unprecedented situation calls for rapid and accurate mathematical models to best inform public health policies. We develop an original parsimonious discrete-time model that accounts for the effect of the age of infection on the natural history of the disease. Analysing the ongoing COVID-19 in France as a test case, through the publicly available time series of nationwide hospital mortality and ICU activity, we estimate the value of the key epidemiological parameters and the impact of lock-down implementation delay. This work shows that including memory-effects in the modelling of COVID-19 spreading greatly improves the accuracy of the fit to the epidemiological data. We estimate that the epidemic wave in France started on Jan 20 [Jan 12, Jan 28] (95% likelihood interval) with a reproduction number initially equal to 2.99 [2.59, 3.39], which was reduced by the national lock-down started on Mar 17 to 24 [21, 27] of its value. We also estimate that the implementation of the latter a week earlier or later would have lead to a difference of about respectively -13k and +50k hospital deaths by the end of lock-down. The present parsimonious discrete-time framework constitutes a useful tool for now- and forecasting simultaneously community incidence and ICU capacity strain.
Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Discrete-time modelling; Epidemiosurveillance; Mathematical epidemiology; Non-Markovian processes; Reproduction number

Year:  2021        PMID: 34015676     DOI: 10.1016/j.epidem.2021.100459

Source DB:  PubMed          Journal:  Epidemics        ISSN: 1878-0067            Impact factor:   4.396


  10 in total

1.  Back to the Roots: A Discrete Kermack-McKendrick Model Adapted to Covid-19.

Authors:  Matthias Kreck; Erhard Scholz
Journal:  Bull Math Biol       Date:  2022-02-17       Impact factor: 1.758

2.  From individual-based epidemic models to McKendrick-von Foerster PDEs: a guide to modeling and inferring COVID-19 dynamics.

Authors:  Félix Foutel-Rodier; François Blanquart; Philibert Courau; Peter Czuppon; Jean-Jil Duchamps; Jasmine Gamblin; Élise Kerdoncuff; Rob Kulathinal; Léo Régnier; Laura Vuduc; Amaury Lambert; Emmanuel Schertzer
Journal:  J Math Biol       Date:  2022-09-28       Impact factor: 2.164

3.  Analysing different exposures identifies that wearing masks and establishing COVID-19 areas reduce secondary-attack risk in aged-care facilities.

Authors:  Bastien Reyné; Christian Selinger; Mircea T Sofonea; Stéphanie Miot; Amandine Pisoni; Edouard Tuaillon; Jean Bousquet; Hubert Blain; Samuel Alizon
Journal:  Int J Epidemiol       Date:  2021-06-21       Impact factor: 9.685

4.  Principles of mathematical epidemiology and compartmental modelling application to COVID-19.

Authors:  Bastien Reyné; Nicolas Saby; Mircea T Sofonea
Journal:  Anaesth Crit Care Pain Med       Date:  2021-12-28       Impact factor: 4.132

5.  Epidemic models: why and how to use them.

Authors:  Mircea T Sofonea; Simon Cauchemez; Pierre-Yves Boëlle
Journal:  Anaesth Crit Care Pain Med       Date:  2022-02-28       Impact factor: 7.025

6.  Epidemiological and clinical insights from SARS-CoV-2 RT-PCR crossing threshold values, France, January to November 2020.

Authors:  Samuel Alizon; Christian Selinger; Mircea T Sofonea; Stéphanie Haim-Boukobza; Jean-Marc Giannoli; Laetitia Ninove; Sylvie Pillet; Vincent Thibault; Alexis de Rougemont; Camille Tumiotto; Morgane Solis; Robin Stephan; Céline Bressollette-Bodin; Maud Salmona; Anne-Sophie L'Honneur; Sylvie Behillil; Caroline Lefeuvre; Julia Dina; Sébastien Hantz; Cédric Hartard; David Veyer; Héloïse M Delagrèverie; Slim Fourati; Benoît Visseaux; Cécile Henquell; Bruno Lina; Vincent Foulongne; Sonia Burrel
Journal:  Euro Surveill       Date:  2022-02

7.  Estimating data-driven coronavirus disease 2019 mitigation strategies for safe university reopening.

Authors:  Qihui Yang; Don M Gruenbacher; Caterina M Scoglio
Journal:  J R Soc Interface       Date:  2022-03-14       Impact factor: 4.118

8.  Analyzing and Modeling the Spread of SARS-CoV-2 Omicron Lineages BA.1 and BA.2, France, September 2021-February 2022.

Authors:  Mircea T Sofonea; Bénédicte Roquebert; Vincent Foulongne; David Morquin; Laura Verdurme; Sabine Trombert-Paolantoni; Mathilde Roussel; Jean-Christophe Bonetti; Judith Zerah; Stéphanie Haim-Boukobza; Samuel Alizon
Journal:  Emerg Infect Dis       Date:  2022-05-31       Impact factor: 16.126

9.  Analysing different exposures identifies that wearing masks and establishing COVID-19 areas reduce secondary-attack risk in aged-care facilities.

Authors:  Bastien Reyné; Christian Selinger; Mircea T Sofonea; Stéphanie Miot; Amandine Pisoni; Edouard Tuaillon; Jean Bousquet; Hubert Blain; Samuel Alizon
Journal:  Int J Epidemiol       Date:  2021-06-21       Impact factor: 7.196

10.  Rapid spread of the SARS-CoV-2 Delta variant in some French regions, June 2021.

Authors:  Samuel Alizon; Stéphanie Haim-Boukobza; Vincent Foulongne; Laura Verdurme; Sabine Trombert-Paolantoni; Emmanuel Lecorche; Bénédicte Roquebert; Mircea T Sofonea
Journal:  Euro Surveill       Date:  2021-07
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.