Literature DB >> 33980300

Ozone therapy as an alternative method for the treatment of diabetic foot ulcer: a case report.

Navid Faraji1, Rasoul Goli2, Babak Choobianzali3, Soheyla Bahrami4, Ali Sadeghian5, Nazila Sepehrnia6, Mahmoodreza Ghalandari1.   

Abstract

BACKGROUND: Diabetic foot ulcer (DFU) is one of the most important complications of diabetes that can lead to amputation. Treatment of DFUs is a major challenge and places a heavy economic and social burden on patients and their families. CASE
PRESENTATION: The present case report is of a 52-year-old kurdish male patient with a 7-year history of type 2 diabetes. While on a bike ride, he sustained a traumatic injury to his right leg, which caused a deep gash measuring 14 × 5 cm on the tibia. During the hospital stay, no improvement was observed after routine wound care including suturing, antibiotic therapy, and dressing change. The patient was referred to our wound-care team. In the first step, the necrotic tissues of his foot ulcer were irrigated and then debrided using mechanical debridement and saline. Next, the patient underwent a 70 μg/dL dose of ozone therapy over a 30-day period in 10 sessions (one 20-minute session every 3 days). Between each session, the patient's wound was wrapped in silver-containing gauze bandages. After 1 month of wound-care using ozone therapy, the patient's foot ulcer had healed and he was discharged from our wound-care service with a stable and good general condition.
CONCLUSION: Considering the effectiveness of ozone therapy along with silver-containing dressing in the treatment of DFUs, wound-care teams can utilize it as an adjunct to the standard methods of DFU treatment.

Entities:  

Keywords:  Diabetic foot; Infection; Ozone; Silver; Wound

Mesh:

Substances:

Year:  2021        PMID: 33980300     DOI: 10.1186/s13256-021-02829-y

Source DB:  PubMed          Journal:  J Med Case Rep        ISSN: 1752-1947


  11 in total

Review 1.  Pathogenesis and treatment of impaired wound healing in diabetes mellitus: new insights.

Authors:  Dimitrios Baltzis; Ioanna Eleftheriadou; Aristidis Veves
Journal:  Adv Ther       Date:  2014-07-29       Impact factor: 3.845

2.  Ozone therapy effectiveness in patients with ulcerous lesions due to diabetes mellitus.

Authors:  Myroslav V Rosul; Bohdan M Patskan
Journal:  Wiad Lek       Date:  2016

3.  Familial Dysalbuminemic Hyperthyroxinemia (FDH), Albumin Gene Variant (R218S), and Risk of Miscarriages in Offspring.

Authors:  Shuiqing Lai; Geetha Gopalakrishnan; Jie Li; Xin Liu; Yuancheng Chen; Yuqiong Wen; Shuting Zhang; Bizhu Huang; Chanika Phornphutkul; Simin Liu; Jian Kuang
Journal:  Am J Med Sci       Date:  2020-05-28       Impact factor: 2.378

4.  2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections.

Authors:  Benjamin A Lipsky; Anthony R Berendt; Paul B Cornia; James C Pile; Edgar J G Peters; David G Armstrong; H Gunner Deery; John M Embil; Warren S Joseph; Adolf W Karchmer; Michael S Pinzur; Eric Senneville
Journal:  Clin Infect Dis       Date:  2012-06       Impact factor: 9.079

5.  Diabetic foot infection: A critical complication.

Authors:  Jennifer J Hurlow; Gavin J Humphreys; Frank L Bowling; Andrew J McBain
Journal:  Int Wound J       Date:  2018-05-28       Impact factor: 3.315

6.  Ozone Therapy on Reduction of Bacterial Colonies and Acceleration of Diabetic Foot Ulcer Healing.

Authors:  Kasmawati Kadir; Yuliana Syam; Saldy Yusuf; Masriani Zainuddin
Journal:  Home Healthc Now       Date:  2020 Jul/Aug

Review 7.  Prevention and treatment of diabetic foot ulcers.

Authors:  Jonathan Zhang Ming Lim; Natasha Su Lynn Ng; Cecil Thomas
Journal:  J R Soc Med       Date:  2017-01-24       Impact factor: 5.344

8.  Efficacy of comprehensive ozone therapy in diabetic foot ulcer healing.

Authors:  Morteza Izadi; Ramin Kheirjou; Roya Mohammadpour; Mohammad Hassan Aliyoldashi; Saeedreza Jamali Moghadam; Farzin Khorvash; Nematollah Jonaidi Jafari; Shahram Shirvani; Nahid Khalili
Journal:  Diabetes Metab Syndr       Date:  2018-12-01

9.  Ozone therapy: A clinical review.

Authors:  A M Elvis; J S Ekta
Journal:  J Nat Sci Biol Med       Date:  2011-01

Review 10.  Ozone therapy: an overview of pharmacodynamics, current research, and clinical utility.

Authors:  Noel L Smith; Anthony L Wilson; Jason Gandhi; Sohrab Vatsia; Sardar Ali Khan
Journal:  Med Gas Res       Date:  2017-10-17
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  4 in total

1.  Surgical debridement and maggot debridement therapy (MDT) bring the light of hope to patients with diabetic foot ulcers (DFUs): A case report.

Authors:  Naser Parizad; Kazem Hajimohammadi; Rasoul Goli; Yousef Mohammadpour; Navid Faraji; Khadijeh Makhdomi
Journal:  Int J Surg Case Rep       Date:  2022-10-05

2.  Ending surgical site infection by negative pressure wound therapy (NPWT): A case report.

Authors:  Mansour Arad; Rasoul Goli; Mazhar Ebrahimzade; Mohammad Lorzini; Mahnaz Abdali; Nazila Sepehrnia
Journal:  Int J Surg Case Rep       Date:  2022-04-12

3.  Wearable adjunct ozone and antibiotic therapy system for treatment of Gram-negative dermal bacterial infection.

Authors:  Alexander Roth; Murali Kannan Maruthamuthu; Sina Nejati; Akshay Krishnakumar; Vidhya Selvamani; Sotoudeh Sedaghat; Juliane Nguyen; Mohamed N Seleem; Rahim Rahimi
Journal:  Sci Rep       Date:  2022-08-17       Impact factor: 4.996

4.  The Relationship between Ozone and Human Blood in the Course of a Well-Controlled, Mild, and Transitory Oxidative Eustress.

Authors:  Gerardo Tricarico; Valter Travagli
Journal:  Antioxidants (Basel)       Date:  2021-12-04
  4 in total

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