Literature DB >> 3395105

Treatment of uncomplicated gonorrhea with single-dose imipenem-cilastatin.

M S Verdon1, F N Judson, J M Ehret, C J Root, E W Hook, W M McCormack, C A Frances, K Draft, J W Shands, H H Handsfield.   

Abstract

Single 500-mg intramuscular doses of imipenem-cilastatin cured 116 (95%) of 122 men and 9 of 9 women with uncomplicated gonorrhea due to beta-lactamase-negative Neisseria gonorrhoeae. Most co-existing Chlamydia trachomatis infections persisted. Imipenem-cilastatin is effective for uncomplicated gonorrhea in men but has no advantages over other available regimens.

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Year:  1988        PMID： 3395105      PMCID： PMC172272          DOI： 10.1128/AAC.32.5.773

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

1.  Chromogenic cephalosporin spot test to detect beta-lactamase in clinically significant bacteria.

Authors:  K Montgomery; L Raymundo; W L Drew
Journal:  J Clin Microbiol       Date:  1979-02       Impact factor: 5.948

2.  A community-based outbreak of infection with penicillin-resistant Neisseria gonorrhoeae not producing penicillinase (chromosomally mediated resistance).

Authors:  H Faruki; R N Kohmescher; W P McKinney; P F Sparling
Journal:  N Engl J Med       Date:  1985-09-05       Impact factor: 91.245

3.  Single doses of methacycline and doxycycline for gonorrhea: a cooperative study of the frequency and cause of treatment failure.

Authors:  P J Wiesner; K K Holmes; P F Sparling; M J Maness; D M Bear; L T Gutman; W W Karney
Journal:  J Infect Dis       Date:  1973-04       Impact factor: 5.226

4.  In vitro susceptibility and cross-resistance of South African isolates of Neisseria gonorrhoeae to 14 antimicrobial agents.

Authors:  L D Liebowitz; R C Ballard; H J Koornhof
Journal:  Antimicrob Agents Chemother       Date:  1982-10       Impact factor: 5.191

5.  Ampicillin resistance in Haemophilus influenzae as determined by a rapid test for beta-lactamase production.

Authors:  C Thornsberry; L A Kirven
Journal:  Antimicrob Agents Chemother       Date:  1974-11       Impact factor: 5.191

Review 6.  Thienamycin: development of imipenen-cilastatin.

Authors:  F M Kahan; H Kropp; J G Sundelof; J Birnbaum
Journal:  J Antimicrob Chemother       Date:  1983-12       Impact factor: 5.790

7.  Detection of Chlamydia trachomatis inclusions in Mccoy cell cultures with fluorescein-conjugated monoclonal antibodies.

Authors:  W E Stamm; M Tam; M Koester; L Cles
Journal:  J Clin Microbiol       Date:  1983-04       Impact factor: 5.948

8.  Microtest procedure for isolation of Chlamydia trachomatis.

Authors:  B L Yoder; W E Stamm; C M Koester; E R Alexander
Journal:  J Clin Microbiol       Date:  1981-06       Impact factor: 5.948

9.  Epidemiology of penicillinase-producing Neisseria gonorrhoeae infections: analysis by auxotyping and serogrouping.

Authors:  H H Handsfield; E G Sandström; J S Knapp; P L Perine; W L Whittington; D E Sayers; K K Holmes
Journal:  N Engl J Med       Date:  1982-04-22       Impact factor: 91.245

Review 10.  Gonococcal infections.

Authors:  E W Hook; K K Holmes
Journal:  Ann Intern Med       Date:  1985-02       Impact factor: 25.391
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