Literature DB >> 33948750

Biomechanical analysis of lumbar interbody fusion supplemented with various posterior stabilization systems.

Wei Fan1, Li-Xin Guo2, Ming Zhang3.   

Abstract

PURPOSE: Biomechanical comparison between rigid and non-rigid posterior stabilization systems following lumbar interbody fusion has been conducted in several studies. However, most of these previous studies mainly focused on investigating biomechanics of adjacent spinal segments or spine stability. The objective of the present study was to compare biomechanical responses of the fusion devices when using different posterior instrumentations.
METHODS: Finite-element model of the intact human lumbar spine (L1-sacrum) was modified to simulate implantation of the fusion cage at L4-L5 level supplemented with different posterior stabilization systems including (i) pedicle screw-based fixation using rigid connecting rods (titanium rods), (ii) pedicle screw-based fixation using flexible connecting rods (PEEK rods) and (iii) dynamic interspinous spacer (DIAM). Stress responses were compared among these various models under bending moments.
RESULTS: The highest and lowest stresses in endplate, fusion cage and bone graft were found at the fused L4-L5 level with DIAM and titanium rod stabilization systems, respectively. When using PEEK rod for the pedicle screw fixation, peak stress in the pedicle screw was lower but the ratio of peak stress in the rods to yield stress of the rod material was higher than using titanium rod.
CONCLUSIONS: Compared with conventional rigid posterior stabilization system, the use of non-rigid stabilization system (i.e., the PEEK rod system and DIAM system) following lumbar interbody fusion might increase the risks of cage subsidence and cage damage, but promote bony fusion due to higher stress in the bone graft. For the pedicle screw-based rod stabilization system, using PEEK rod might reduce the risk of screw breakage but increased breakage risk of the rod itself.

Entities:  

Keywords:  Biomechanics; Finite element; Lumbar interbody fusion; Non-rigid stabilization system; Rigid stabilization system

Year:  2021        PMID: 33948750     DOI: 10.1007/s00586-021-06856-7

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  35 in total

1.  Spinal-fusion surgery - the case for restraint.

Authors:  Richard A Deyo; Alf Nachemson; Sohail K Mirza
Journal:  N Engl J Med       Date:  2004-02-12       Impact factor: 91.245

Review 2.  Clinical and biomechanical researches of polyetheretherketone (PEEK) rods for semi-rigid lumbar fusion: a systematic review.

Authors:  Chan Li; Lei Liu; Jian-Yong Shi; Kai-Zhong Yan; Wei-Zhong Shen; Zhen-Rong Yang
Journal:  Neurosurg Rev       Date:  2016-07-08       Impact factor: 3.042

Review 3.  Adjacent segment disease after lumbar or lumbosacral fusion: review of the literature.

Authors:  Paul Park; Hugh J Garton; Vishal C Gala; Julian T Hoff; John E McGillicuddy
Journal:  Spine (Phila Pa 1976)       Date:  2004-09-01       Impact factor: 3.468

4.  Comparison of the load-sharing characteristics between pedicle-based dynamic and rigid rod devices.

Authors:  Yoon-Ho Ahn; Wen-Ming Chen; Kwon-Yong Lee; Kyung-Woo Park; Sung-Jae Lee
Journal:  Biomed Mater       Date:  2008-11-25       Impact factor: 3.715

5.  Biomechanical in vitro comparison between anterior column realignment and pedicle subtraction osteotomy for severe sagittal imbalance correction.

Authors:  Luigi La Barbera; Hans-Joachim Wilke; Christian Liebsch; Tomaso Villa; Andrea Luca; Fabio Galbusera; Marco Brayda-Bruno
Journal:  Eur Spine J       Date:  2019-08-14       Impact factor: 3.134

6.  A comparison of the influence of three different lumbar interbody fusion approaches on stress in the pedicle screw fixation system: Finite element static and vibration analyses.

Authors:  Wei Fan; Li-Xin Guo
Journal:  Int J Numer Method Biomed Eng       Date:  2018-10-30       Impact factor: 2.747

Review 7.  A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned.

Authors:  Eugene J Carragee; Eric L Hurwitz; Bradley K Weiner
Journal:  Spine J       Date:  2011-06       Impact factor: 4.166

Review 8.  Lumbar interbody fusion: techniques, indications and comparison of interbody fusion options including PLIF, TLIF, MI-TLIF, OLIF/ATP, LLIF and ALIF.

Authors:  Ralph J Mobbs; Kevin Phan; Greg Malham; Kevin Seex; Prashanth J Rao
Journal:  J Spine Surg       Date:  2015-12

9.  Pelvic plexus tumors.

Authors:  Kurtus Dafford; Daniel Kim; Natasha Reid; David Kline
Journal:  Neurosurg Focus       Date:  2007-06-15       Impact factor: 4.047

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  3 in total

1.  Deterioration of the fixation segment's stress distribution and the strength reduction of screw holding position together cause screw loosening in ALSR fixed OLIF patients with poor BMD.

Authors:  Jing-Chi Li; Zhi-Qiang Yang; Tian-Hang Xie; Zhe-Tao Song; Yue-Ming Song; Jian-Cheng Zeng
Journal:  Front Bioeng Biotechnol       Date:  2022-08-30

2.  The Mismatch Between Bony Endplates and Grafted Bone Increases Screw Loosening Risk for OLIF Patients With ALSR Fixation Biomechanically.

Authors:  Jing-Chi Li; Tian-Hang Xie; Zhuang Zhang; Zhe-Tao Song; Yue-Ming Song; Jian-Cheng Zeng
Journal:  Front Bioeng Biotechnol       Date:  2022-04-08

3.  Biomechanical Effects of Pedicle Screw Positioning on the Surgical Segment in Models After Oblique Lumbar Interbody Fusion: An in-silico Study.

Authors:  Chen Xu; Chenyi Huang; Ping Cai; Zhongxin Fang; Zhangchao Wei; Fei Liu; Jingchi Li; Yang Liu
Journal:  Int J Gen Med       Date:  2022-02-02
  3 in total

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