Literature DB >> 33876913

Elimination of the Perinatal Transmission of HIV and Syphilis in Puerto Rico and Sustained Success since 2007: Convergence of Science, Women-Centered Care, and Policy.

Carmen D Zorrilla1, Linnette Rodríguez-Figueroa2, Sandra Miranda-De León3, Bernardita López-Alvarado3, Eileen Pérez4, Silvia E Rabionet5.   

Abstract

OBJECTIVE: There have been significant successes in the fight against HIV/AIDS due to the access to rapid HIV testing, interventions to reduce the mother-to-child transmission (MTCT) risk, potent and effective antiviral medications, and other biomedical prevention strategies. The purpose of this work is to demonstrate that Puerto Rico eliminated Mother-to-Child Transmission of HIV (MTCT) following the 2017 World Health Organization (WHO) criteria for validating the elimination of MTCT and Syphilis.
METHODS: Existing epidemiological data from Puerto Rico was used to document the elimination of MTCT and Syphilis. Data to calculate the indicators was obtained from the various divisions of the Puerto Rico Department of Health, including vital statistics, surveillance data, and programmatic outcomes.
RESULTS: Puerto Rico eliminated MTCT and syphilis, according to the WHO indicators, earlier than other countries. We can trace the outcomes to 1994 using the incidence rate of perinatally-acquired HIV of <50/100,000; to 2007 using HIV perinatal transmission rates for non-breastfeeding countries (<2%), to 2008 using 90% of women receiving ART at delivery, and to 2005 using the incidence rate of congenital syphilis of <50/100,000.
CONCLUSION: Not only have we eliminated the MTCT of HIV and syphilis, but the efforts have been sustained since 2000. The elimination of transmission of infectious diseases requires the intersection of scientific feasibility, coordinated interventions, and political will, successfully attained in Puerto Rico.

Entities:  

Keywords:  Elimination of Mother to Child HIV Transmission; HIV and Syphilis; HIV and pregnancy; Perinatal HIV transmission; Women-centered HIV Care

Mesh:

Year:  2021        PMID: 33876913      PMCID: PMC8363176     

Source DB:  PubMed          Journal:  P R Health Sci J        ISSN: 0738-0658            Impact factor:   0.705


  8 in total

1.  UK Mother-to-Child HIV Transmission Rates Continue to Decline: 2012-2014.

Authors:  Helen Peters; Kate Francis; Rebecca Sconza; Anna Horn; Catherine S Peckham; Pat A Tookey; Claire Thorne
Journal:  Clin Infect Dis       Date:  2017-02-15       Impact factor: 9.079

2.  Reconsidering the Number of Women With HIV Infection Who Give Birth Annually in the United States.

Authors:  Steven R Nesheim; Lauren F FitzHarris; Margaret A Lampe; Kristen Mahle Gray
Journal:  Public Health Rep       Date:  2018-09-28       Impact factor: 2.792

3.  The shape of the HIV/AIDS epidemic in Puerto Rico.

Authors:  M A Gomez; D M Fernandez; J F Otero; S Miranda; R Hunter
Journal:  Rev Panam Salud Publica       Date:  2000-06

4.  Zidovudine for the prevention of HIV transmission from mother to infant.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  1994-04-29       Impact factor: 17.586

5.  Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group.

Authors:  E M Connor; R S Sperling; R Gelber; P Kiselev; G Scott; M J O'Sullivan; R VanDyke; M Bey; W Shearer; R L Jacobson
Journal:  N Engl J Med       Date:  1994-11-03       Impact factor: 91.245

6.  Brief Report: Estimated Incidence of Perinatally Acquired HIV Infection in the United States, 1978-2013.

Authors:  Steven R Nesheim; Jeffrey Wiener; Lauren F Fitz Harris; Margaret A Lampe; Paul J Weidle
Journal:  J Acquir Immune Defic Syndr       Date:  2017-12-15       Impact factor: 3.731

7.  Reduction in the perinatal HIV transmission: the experience at the Maternal Infant Studies Center and Gamma Projects at the University of Puerto Rico School of Medicine.

Authors:  Carmen D Zorrilla; Vivian Tamayo Agrait; Irma Febo; Lydia E Santiago; Clemente Díaz; Iraida Salabarría; Eileen Pérez; George V Hillyer
Journal:  P R Health Sci J       Date:  2007-12       Impact factor: 0.705

8.  U.S. Public Health Service recommendations for human immunodeficiency virus counseling and voluntary testing for pregnant women.

Authors: 
Journal:  MMWR Recomm Rep       Date:  1995-07-07
  8 in total
  3 in total

1.  Management Solutions for the Restructuring of Laboratories Associated to the Sentinel Services for Syphilis and Other STIs.

Authors:  Karilany Dantas Coutinho; Ricardo A de M Valentim; Geir Veras Vieira; Maíra Sidrim; Pedro Henrique Germano Evangelista; Laís Pereira de Oliveira
Journal:  Front Public Health       Date:  2022-04-29

2.  The Historic Elimination of Mother-to-Child HIV and Syphilis Transmission in Puerto Rico.

Authors:  Sten H Vermund; Irma Febo
Journal:  P R Health Sci J       Date:  2021-03       Impact factor: 0.705

3.  Syphilis response policies and their assessments: A scoping review.

Authors:  Milena C D Almeida; António M R Cordeiro; Aliete Cunha-Oliveira; Daniele M S Barros; Diana G S M Santos; Thaísa S Lima; Ricardo A M Valentim
Journal:  Front Public Health       Date:  2022-09-16
  3 in total

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