Literature DB >> 33837442

[Possibilities and limits of conservative treatment for osteoarthritis : Sport advice, training therapy, orthotics and cartilage therapeutics].

Stefan Nehrer1,2, Markus Neubauer3,4.   

Abstract

BACKGROUND: Osteoarthritis (OA)-the progressive degeneration of synovial joints-is a worldwide problem that affects society, is associated with age and is the dominant reason for pain and immobility of the locomotor system. In the population, 70% of people over the age of 70 show some signs of OA. Overall, up to 25% of the total population is affected, due to the general aging of the population itself, and this is an increasing tendency. However, in people over the age of 40 the incidence of OA is already rising due to posttraumatic or secondary forms, like dysplasia, malalignment and other background factors. CLAIM: There is a high need for mobility and sports in all generations, so the demands on the joints are high, especially if early degenerative changes are already present. Orthopaedic physicians are challenged with the limited load capacity, pain and the progressive joint problems, on the one hand to get the patient back to full mobility, and, on the other, to prevent early joint replacement. Early diagnosis and preventive measurements, as well as conservative treatments-from medication to braces-are necessary to achieve symptom-free movement and joint preservation to avoid joint replacement.

Entities:  

Keywords:  Aging; Athletics; Braces; Conservative therapy; Joints

Year:  2021        PMID: 33837442     DOI: 10.1007/s00132-021-04100-0

Source DB:  PubMed          Journal:  Orthopade        ISSN: 0085-4530            Impact factor:   1.087


  34 in total

Review 1.  Skeletal muscle unweighting: spaceflight and ground-based models.

Authors:  Gregory R Adams; Vincent J Caiozzo; Kenneth M Baldwin
Journal:  J Appl Physiol (1985)       Date:  2003-12

Review 2.  Pathomechanisms of cartilage destruction by mechanical injury.

Authors:  Bodo Kurz; Angelika K Lemke; Jakob Fay; Thomas Pufe; Alan J Grodzinsky; Michael Schünke
Journal:  Ann Anat       Date:  2005-11       Impact factor: 2.698

Review 3.  Effects of aging on articular cartilage homeostasis.

Authors:  Martin Lotz; Richard F Loeser
Journal:  Bone       Date:  2012-03-28       Impact factor: 4.398

4.  Physical workload and the risk of severe knee osteoarthritis.

Authors:  Pirjo Manninen; Markku Heliövaara; Hilkka Riihimäki; Olavi Suoma-Iainen
Journal:  Scand J Work Environ Health       Date:  2002-02       Impact factor: 5.024

5.  Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment.

Authors:  Ok Hee Jeon; Chaekyu Kim; Remi-Martin Laberge; Marco Demaria; Sona Rathod; Alain P Vasserot; Jae Wook Chung; Do Hun Kim; Yan Poon; Nathaniel David; Darren J Baker; Jan M van Deursen; Judith Campisi; Jennifer H Elisseeff
Journal:  Nat Med       Date:  2017-04-24       Impact factor: 53.440

6.  Quadriceps femoris muscle weakness and activation failure in patients with symptomatic knee osteoarthritis.

Authors:  Michael D Lewek; Katherine S Rudolph; Lynn Snyder-Mackler
Journal:  J Orthop Res       Date:  2004-01       Impact factor: 3.494

Review 7.  Articular cartilage: structure, injuries and review of management.

Authors:  Abhijit M Bhosale; James B Richardson
Journal:  Br Med Bull       Date:  2008-08-01       Impact factor: 4.291

Review 8.  Cellular ageing mechanisms in osteoarthritis.

Authors:  P K Sacitharan; T L Vincent
Journal:  Mamm Genome       Date:  2016-05-23       Impact factor: 2.957

9.  Stratification of knee osteoarthritis: two major patient subgroups identified by genome-wide expression analysis of articular cartilage.

Authors:  Jamie Soul; Sara L Dunn; Sanjay Anand; Ferdinand Serracino-Inglott; Jean-Marc Schwartz; Ray P Boot-Handford; Tim E Hardingham
Journal:  Ann Rheum Dis       Date:  2017-12-22       Impact factor: 19.103

10.  Concentration-Dependent Effects of Cobalt and Chromium Ions on Osteoarthritic Chondrocytes.

Authors:  Christoph Bauer; Christoph Stotter; Vivek Jeyakumar; Eugenia Niculescu-Morzsa; Bojana Simlinger; Manel Rodríguez Ripoll; Thomas Klestil; Friedrich Franek; Stefan Nehrer
Journal:  Cartilage       Date:  2019-11-28       Impact factor: 4.634

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