Literature DB >> 33828474

Neurorobotic Models of Neurological Disorders: A Mini Review.

Savva Pronin1,2, Liam Wellacott1, Jhielson Pimentel1, Renan C Moioli3, Patricia A Vargas1.   

Abstract

Modeling is widely used in biomedical research to gain insights into pathophysiology and treatment of neurological disorders but existing models, such as animal models and computational models, are limited in generalizability to humans and are restricted in the scope of possible experiments. Robotics offers a potential complementary modeling platform, with advantages such as embodiment and physical environmental interaction yet with easily monitored and adjustable parameters. In this review, we discuss the different types of models used in biomedical research and summarize the existing neurorobotics models of neurological disorders. We detail the pertinent findings of these robot models which would not have been possible through other modeling platforms. We also highlight the existing limitations in a wider uptake of robot models for neurological disorders and suggest future directions for the field.
Copyright © 2021 Pronin, Wellacott, Pimentel, Moioli and Vargas.

Entities:  

Keywords:  artificial neural networks; computational models; neurophysiology; neurorobotics; pathophysiology; robot models; simulation

Year:  2021        PMID: 33828474      PMCID: PMC8020031          DOI: 10.3389/fnbot.2021.634045

Source DB:  PubMed          Journal:  Front Neurorobot        ISSN: 1662-5218            Impact factor:   2.650


  36 in total

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Authors:  Werner Poewe; Klaus Seppi; Caroline M Tanner; Glenda M Halliday; Patrik Brundin; Jens Volkmann; Anette-Eleonore Schrag; Anthony E Lang
Journal:  Nat Rev Dis Primers       Date:  2017-03-23       Impact factor: 52.329

2.  A biophysical model of the cortex-basal ganglia-thalamus network in the 6-OHDA lesioned rat model of Parkinson's disease.

Authors:  Karthik Kumaravelu; David T Brocker; Warren M Grill
Journal:  J Comput Neurosci       Date:  2016-02-11       Impact factor: 1.621

3.  A brief history of animal modeling.

Authors:  Aaron C Ericsson; Marcus J Crim; Craig L Franklin
Journal:  Mo Med       Date:  2013 May-Jun

Review 4.  Insights into Parkinson's disease from computational models of the basal ganglia.

Authors:  Mark D Humphries; Jose Angel Obeso; Jakob Kisbye Dreyer
Journal:  J Neurol Neurosurg Psychiatry       Date:  2018-04-17       Impact factor: 10.154

5.  Dynamic dopamine modulation in the basal ganglia: a neurocomputational account of cognitive deficits in medicated and nonmedicated Parkinsonism.

Authors:  Michael J Frank
Journal:  J Cogn Neurosci       Date:  2005-01       Impact factor: 3.225

6.  The end of the line for a brain-damaged model of unilateral neglect.

Authors:  M C Mozer; P W Halligan; J C Marshall
Journal:  J Cogn Neurosci       Date:  1997-03       Impact factor: 3.225

7.  Generalisation, decision making, and embodiment effects in mental rotation: A neurorobotic architecture tested with a humanoid robot.

Authors:  Kristsana Seepanomwan; Daniele Caligiore; Angelo Cangelosi; Gianluca Baldassarre
Journal:  Neural Netw       Date:  2015-10-03

8.  Hedonic quality or reward? A study of basic pleasure in homeostasis and decision making of a motivated autonomous robot.

Authors:  Matthew Lewis; Lola Cañamero
Journal:  Adapt Behav       Date:  2016-10-12       Impact factor: 1.942

9.  Different Dopaminergic Dysfunctions Underlying Parkinsonian Akinesia and Tremor.

Authors:  Daniele Caligiore; Francesco Mannella; Gianluca Baldassarre
Journal:  Front Neurosci       Date:  2019-05-29       Impact factor: 4.677

10.  The hierarchical and functional connectivity of higher-order cognitive mechanisms: neurorobotic model to investigate the stability and flexibility of working memory.

Authors:  Fady Alnajjar; Yuichi Yamashita; Jun Tani
Journal:  Front Neurorobot       Date:  2013-02-18       Impact factor: 2.650

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  1 in total

1.  Neuro4PD: An Initial Neurorobotics Model of Parkinson's Disease.

Authors:  Jhielson M Pimentel; Renan C Moioli; Mariana F P de Araujo; Caetano M Ranieri; Roseli A F Romero; Frank Broz; Patricia A Vargas
Journal:  Front Neurorobot       Date:  2021-07-01       Impact factor: 2.650

  1 in total

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