Literature DB >> 33814608

Intraoperative Cell Saving: Is the Solution the Actual Problem?

Krishnan Pillay1, Shobashini Perumal1.   

Abstract

Allogenic blood is a scarce, precious, and expensive resource that is not always available on demand. After termination of cardiopulmonary bypass, a large amount of residual pump blood remains in the extracorporeal circuit. The cell saver washes and concentrates this blood with .9% normal saline (NS), making autologous blood available and reducing the demand for allogenic blood. To quantify the quality of residual pump blood it was washed with either NS or a bicarbonate-buffered solution (Balsol). A qualitative in vitro analysis was conducted. Residual cardiopulmonary bypass blood from forty bypass circuits was processed with a cell saver device, using NS or Balsol solution. Measurements made compared the pH, electrolytes, metabolites, hematocrit, hemoglobin, osmolality, albumin, total protein, and strong ion difference. There were significant differences between the NS and Balsol groups. In the Balsol group, osmolality, electrolytes, and strong ion difference were similar to the constitution of Balsol solution after washing, but not with the normal saline group. Washing residual cardiopulmonary bypass pump blood with Balsol solution results in a resuspended red cell concentrate with a superior electrolyte profile and a strong ion difference similar to that of residual pump blood. © Copyright 2021 AMSECT.

Entities:  

Year:  2021        PMID: 33814608      PMCID: PMC7995625          DOI: 10.1182/ject-2000047

Source DB:  PubMed          Journal:  J Extra Corpor Technol        ISSN: 0022-1058


  29 in total

1.  Quality of red blood cells using autotransfusion devices: a comparative analysis.

Authors:  Cyril J Serrick; Mary Scholz; Arthur Melo; Onkar Singh; Dionne Noel
Journal:  J Extra Corpor Technol       Date:  2003-03

2.  Dilutional hypokalemia-induced arrhythmias associated with intraoperative cell salvage and reinfusion.

Authors:  Yong G Peng; Gregory M Janelle; Erik R Perschau; Matthew D Forthofer; Nikolaus Gravenstein
Journal:  J Cardiothorac Vasc Anesth       Date:  2006-01-06       Impact factor: 2.628

3.  Washing of stored red blood cells by an autotransfusion device before transfusion.

Authors:  R de Vroege; W R Wildevuur; J A G Muradin; D Graves; W van Oeveren
Journal:  Vox Sang       Date:  2007-02       Impact factor: 2.144

4.  Acid-base effects of a bicarbonate-balanced priming fluid during cardiopulmonary bypass: comparison with Plasma-Lyte 148. A randomised single-blinded study.

Authors:  T J Morgan; G Power; B Venkatesh; M A Jones
Journal:  Anaesth Intensive Care       Date:  2008-11       Impact factor: 1.669

5.  Isolyte S, a physiologic multielectrolyte solution, is preferable to normal saline to wash cell saver salvaged blood: conclusions from a prospective, randomized study in a canine model.

Authors:  N A Halpern; M Alicea; B Seabrook; A Spungen; R Greenstein
Journal:  Crit Care Med       Date:  1997-12       Impact factor: 7.598

6.  Crystalloid strong ion difference determines metabolic acid-base change during acute normovolaemic haemodilution.

Authors:  Thomas J Morgan; Balasubramanian Venkatesh; Jonathan Hall
Journal:  Intensive Care Med       Date:  2004-02-28       Impact factor: 17.440

7.  A randomized, controlled, double-blind crossover study on the effects of 2-L infusions of 0.9% saline and plasma-lyte® 148 on renal blood flow velocity and renal cortical tissue perfusion in healthy volunteers.

Authors:  Abeed H Chowdhury; Eleanor F Cox; Susan T Francis; Dileep N Lobo
Journal:  Ann Surg       Date:  2012-07       Impact factor: 12.969

8.  Application of the continuous autotransfusion system (CATS) to prevent transfusion-related hyperkalemia following hyperkalemic cardiac arrest in an infant -A case report-.

Authors:  Hye-Min Sohn; Yong-Hee Park; Hyo-Jin Byon; Jin-Tae Kim; Hee-Soo Kim; Chong Sung Kim
Journal:  Korean J Anesthesiol       Date:  2012-03-21

9.  Severe electrolyte disorders following cardiac surgery: a prospective controlled observational study.

Authors:  Kees H Polderman; Armand R J Girbes
Journal:  Crit Care       Date:  2004-10-22       Impact factor: 9.097

10.  Cell salvage using the continuous autotransfusion device CATSmart - an observational bicenter technical evaluation.

Authors:  Simone Lindau; Madeline Kohlhaas; Michael Nosch; Suma Choorapoikayil; Kai Zacharowski; Patrick Meybohm
Journal:  BMC Anesthesiol       Date:  2018-12-12       Impact factor: 2.217

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