Literature DB >> 33801919

Pharmacogenomic Determinants of Interindividual Drug Response Variability: From Discovery to Implementation.

Stuart A Scott1,2, Jesse J Swen3.   

Abstract

Since the term "pharmacogenetics" was first published in the late 1950s by Friedrich Vogel, the field has evolved into genome-wide association studies identifying novel variants associated with drug response phenotypes, international societies and consortia dedicated to pharmacogenomic research and clinical implementation, clinical practice guidelines, and the increasing availability of pharmacogenomic tests for healthcare providers in both hospital and primary care [...].

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Year:  2021        PMID: 33801919      PMCID: PMC7999913          DOI: 10.3390/genes12030393

Source DB:  PubMed          Journal:  Genes (Basel)        ISSN: 2073-4425            Impact factor:   4.096


  15 in total

1.  Profile of the Nicotinic Cholinergic Receptor Alpha 7 Subunit Gene Expression is Associated with Response to Varenicline Treatment.

Authors:  Juliana Rocha Santos; Paulo Roberto Xavier Tomaz; Jaqueline Ribeiro Scholz; Patrícia Viviane Gaya; Tânia Ogawa Abe; José Eduardo Krieger; Alexandre Costa Pereira; Paulo Caleb Júnior de Lima Santos
Journal:  Genes (Basel)       Date:  2020-07-06       Impact factor: 4.096

Review 2.  Comparison of the Impact of Pharmacogenetic Variability on the PK of Slow Release and Immediate Release Tacrolimus Formulations.

Authors:  Teun van Gelder; Oumaima Etsouli; Dirk Jan Moes; Jesse J Swen
Journal:  Genes (Basel)       Date:  2020-10-15       Impact factor: 4.096

3.  Genetic Variants Affecting Anti-VEGF Drug Response in Polypoidal Choroidal Vasculopathy Patients: A Systematic Review and Meta-Analysis.

Authors:  Xando Díaz-Villamarín; David Blánquez-Martínez; Ana Pozo-Agundo; Ana María Pérez-Gutiérrez; José Ignacio Muñoz-Ávila; Alba Antúnez-Rodríguez; Ana Estefanía Fernández-Gómez; Paloma García-Navas; Luis Javier Martínez-González; Cristina Lucía Dávila-Fajardo
Journal:  Genes (Basel)       Date:  2020-11-12       Impact factor: 4.096

Review 4.  Technologies for Pharmacogenomics: A Review.

Authors:  Maaike van der Lee; Marjolein Kriek; Henk-Jan Guchelaar; Jesse J Swen
Journal:  Genes (Basel)       Date:  2020-12-04       Impact factor: 4.096

5.  Using Personal Genomic Data within Primary Care: A Bioinformatics Approach to Pharmacogenomics.

Authors:  Rick Overkleeft; Judith Tommel; Andrea W M Evers; Johan T den Dunnen; Marco Roos; Marie-José Hoefmans; Walter E Schrader; Jesse J Swen; Mattijs E Numans; Elisa J F Houwink
Journal:  Genes (Basel)       Date:  2020-11-30       Impact factor: 4.096

6.  Genome-Wide Association Study of Metamizole-Induced Agranulocytosis in European Populations.

Authors:  Anca Liliana Cismaru; Deborah Rudin; Luisa Ibañez; Evangelia Liakoni; Nicolas Bonadies; Reinhold Kreutz; Alfonso Carvajal; Maria Isabel Lucena; Javier Martin; Esther Sancho Ponce; Mariam Molokhia; Niclas Eriksson; Stephan Krähenbühl; Carlo R Largiadèr; Manuel Haschke; Pär Hallberg; Mia Wadelius; Ursula Amstutz
Journal:  Genes (Basel)       Date:  2020-10-29       Impact factor: 4.096

7.  Association of NUDT15*3 and FPGS 2572C>T Variants with the Risk of Early Hematologic Toxicity During 6-MP and Low-Dose Methotrexate-Based Maintenance Therapy in Indian Patients with Acute Lymphoblastic Leukemia.

Authors:  Sunitha Kodidela; Patchava Dorababu; Dimpal N Thakkar; Biswajit Dubashi; Rajan Sundaram; Niveditha Muralidharan; Ravi Prasad Nidanapu; Anil Aribandi; Suresh Chandra Pradhan; Chakradhara Rao Satyanarayana Uppugunduri
Journal:  Genes (Basel)       Date:  2020-05-28       Impact factor: 4.096

Review 8.  A Review of the Important Role of CYP2D6 in Pharmacogenomics.

Authors:  Christopher Taylor; Ian Crosby; Vincent Yip; Peter Maguire; Munir Pirmohamed; Richard M Turner
Journal:  Genes (Basel)       Date:  2020-10-30       Impact factor: 4.096

9.  Phased Haplotype Resolution of the SLC6A4 Promoter Using Long-Read Single Molecule Real-Time (SMRT) Sequencing.

Authors:  Mariana R Botton; Yao Yang; Erick R Scott; Robert J Desnick; Stuart A Scott
Journal:  Genes (Basel)       Date:  2020-11-12       Impact factor: 4.096

Review 10.  Thiopurine Drugs in the Treatment of Ulcerative Colitis: Identification of a Novel Deleterious Mutation in TPMT.

Authors:  Pierre-Olivier Harmand; Jérôme Solassol
Journal:  Genes (Basel)       Date:  2020-10-16       Impact factor: 4.096

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