Datonye Alasia1, Golden Owhonda2, Omosivie Maduka3, Ifeoma Nwadiuto2, Godswill Arugu2, Charles Tobin-West3, Esther Azi4, Victor Oris-Onyiri2, Inwon Joseph Urang5, Victor Abikor2, Ayo-Maria Olofinuka6, Obelebra Adebiyi2, Abiye Somiari7, Hope Avundaa7, Aloni Alali7. 1. Department of Internal Medicine, University of Port Harcourt, Rivers State, Nigeria. 2. Department of Public Health and Disease Control, Rivers State Ministry of Health, Rivers State, Nigeria. 3. Department of Preventive and Social Medicine, University of Port Harcourt, Rivers State, Nigeria. 4. Department of Community Medicine, Rivers State University Port-Harcourt, Nigeria, Rivers State, Nigeria. 5. Department of Community Health, Rivers State Primary Health Care Management Board, Rivers State, Nigeria. 6. World Health Organization Abuja Office, Abuja, Nigeria. 7. Department of Community Medicine, University of Port Harcourt Teaching Hospital, Rivers State, Nigeria.
Abstract
INTRODUCTION: the knowledge of epidemiologic and clinical variables in patients with SARS- CoV-2 infection provides evidence and lessons that are useful for the pandemic response, with consideration of National and sub-National variations. The objective of this study was to characterize and describe the clinical and epidemiologic features of all the hospitalised patients with COVID-19 in Rivers State Nigeria, from March to August 2020. METHODS: a prospective descriptive multi-center study of patients with positive SARS-CoV-2 RT PCR, who were hospitalised for treatment and self-isolation in four treatment centers in Rivers state, Nigeria. RESULTS: the mean age of all the patients was 39.21 ± 12.31 years, with a range of 2 to 77 years. The majority of patients were in the 31 to 40-year (33.0%), 41 to 50-year (23.1%) and 18-to 30-year (22.0%) age groups. The patient population included 474 (73.4%) males and 172 (26.6%) females, with 93 (14.4%) healthcare workers. A history of contact and travel was established in 38.5% and at least one comorbid disease condition was present in 32.8% of patients. Patients with severe disease were 61 (9.45%), while the overall case fatality rate was 2%. The leading comorbid disease conditions were Hypertension in 23.8% and diabetes in 7.7% of patients. Fever (26.0%), dry Cough (17.6%), dyspnoea (12.7%), anosmia (12.7%) and headache (9.9%) were the most common symptoms. The presence of comorbidity and increasing age predicted death from COVID-19. CONCLUSION: the clinical and epidemiologic characteristics of this cohort of hospitalised patients show significant similarities with existing trends from previously reported studies, with contextual peculiarities. Copyright: Datonye Alasia et al.
INTRODUCTION: the knowledge of epidemiologic and clinical variables in patients with SARS- CoV-2 infection provides evidence and lessons that are useful for the pandemic response, with consideration of National and sub-National variations. The objective of this study was to characterize and describe the clinical and epidemiologic features of all the hospitalised patients with COVID-19 in Rivers State Nigeria, from March to August 2020. METHODS: a prospective descriptive multi-center study of patients with positive SARS-CoV-2 RT PCR, who were hospitalised for treatment and self-isolation in four treatment centers in Rivers state, Nigeria. RESULTS: the mean age of all the patients was 39.21 ± 12.31 years, with a range of 2 to 77 years. The majority of patients were in the 31 to 40-year (33.0%), 41 to 50-year (23.1%) and 18-to 30-year (22.0%) age groups. The patient population included 474 (73.4%) males and 172 (26.6%) females, with 93 (14.4%) healthcare workers. A history of contact and travel was established in 38.5% and at least one comorbid disease condition was present in 32.8% of patients. Patients with severe disease were 61 (9.45%), while the overall case fatality rate was 2%. The leading comorbid disease conditions were Hypertension in 23.8% and diabetes in 7.7% of patients. Fever (26.0%), dry Cough (17.6%), dyspnoea (12.7%), anosmia (12.7%) and headache (9.9%) were the most common symptoms. The presence of comorbidity and increasing age predicted death from COVID-19. CONCLUSION: the clinical and epidemiologic characteristics of this cohort of hospitalised patients show significant similarities with existing trends from previously reported studies, with contextual peculiarities. Copyright: Datonye Alasia et al.
Authors: Daniel Pan; Shirley Sze; Jatinder S Minhas; Mansoor N Bangash; Nilesh Pareek; Pip Divall; Caroline Ml Williams; Marco R Oggioni; Iain B Squire; Laura B Nellums; Wasim Hanif; Kamlesh Khunti; Manish Pareek Journal: EClinicalMedicine Date: 2020-06-03
Authors: Lara S Shekerdemian; Nabihah R Mahmood; Katie K Wolfe; Becky J Riggs; Catherine E Ross; Christine A McKiernan; Sabrina M Heidemann; Lawrence C Kleinman; Anita I Sen; Mark W Hall; Margaret A Priestley; John K McGuire; Konstantinos Boukas; Matthew P Sharron; Jeffrey P Burns Journal: JAMA Pediatr Date: 2020-09-01 Impact factor: 16.193