Abimbola Bowale 1 , Akin Abayomi 2 , Jide Idris 2 , Sunday Omilabu 3 , Ismail Abdus-Salam 2 , Busayo Adebayo 4 , Folarin Opawoye 5 , Ore Finnih-Awokoya 6 , Emmanuella Zamba 2 , Hussein Abdur-Razzaq 2 , Olufemi Erinoso 4 , Tosin Onasanya 7 , Patrick Ramadan 8 , Sam Nyenyi 8 , Evaristus Aniaku 9 , Muhammad Balogun 10 , Oyeladun Okunromade 9 , Olusola Adejumo 1 , Sunday Adesola 1 , Tope Ogunniyan 1 , Mobolanle Balogun 3,5 , Akin Osibogun 3,7 Show Affiliations »
Abstract
INTRODUCTION: Success in curtailing the pandemic coronavirus disease (COVID-19) depends largely on a sound understanding of the epidemiologic and clinical profile of cases in a population as well as the case management approach. This study documents the presenting characteristics, treatment modalities and outcomes of the first 32 COVID-19 patients in Nigeria. METHODS: This retrospective study used medical records of the first 32 patients admitted and discharged from the Mainland Hospital, Lagos State, southwest Nigeria between February 27 and April 6, 2020. The outcomes of interest were death, promptness of admission process and duration of hospitalization. RESULTS: The mean age of the patients was 38.1 years (SD: 15.5) and 66% were male. Three-quarters (75%) of the patients presented in moderately severe condition while 16% were asymptomatic. The most common presenting symptoms were fever (59%) and dry cough (44%). The mean time between a positive test result and admission was 1.63 days (SD: 1.31). Almost all (97%) the patients were treated with lopinavir-ritonavir with no recorded death. The median duration of hospital stay was 12 days (IQR: 9-13.5). CONCLUSION: In this preliminary analysis of the first COVID-19 cases in Nigeria, clinical presentation was mild to moderate with no mortality. Processes to improve promptness of admission and reduce hospital stay are required to enhance the response to COVID-19 in Nigeria. ©Abimbola Bowale et al.
INTRODUCTION: Success in curtailing the pandemic coronavirus disease (COVID-19) depends largely on a sound understanding of the epidemiologic and clinical profile of cases in a population as well as the case management approach. This study documents the presenting characteristics, treatment modalities and outcomes of the first 32 COVID-19 patients in Nigeria. METHODS: This retrospective study used medical records of the first 32 patients admitted and discharged from the Mainland Hospital, Lagos State, southwest Nigeria between February 27 and April 6, 2020. The outcomes of interest were death, promptness of admission process and duration of hospitalization. RESULTS: The mean age of the patients was 38.1 years (SD: 15.5) and 66% were male. Three-quarters (75%) of the patients presented in moderately severe condition while 16% were asymptomatic. The most common presenting symptoms were fever (59%) and dry cough (44%). The mean time between a positive test result and admission was 1.63 days (SD: 1.31). Almost all (97%) the patients were treated with lopinavir-ritonavir with no recorded death. The median duration of hospital stay was 12 days (IQR: 9-13.5). CONCLUSION: In this preliminary analysis of the first COVID-19 cases in Nigeria, clinical presentation was mild to moderate with no mortality. Processes to improve promptness of admission and reduce hospital stay are required to enhance the response to COVID-19 in Nigeria. ©Abimbola Bowale et al.
Entities: Chemical
Keywords:
COVID-19 presentation; Nigeria; clinical outcomes; retrospective study
Mesh： See more »
Year: 2020
PMID： 33623549 PMCID： PMC7875732 DOI： 10.11604/pamj.supp.2020.35.2.23262
Source DB: PubMed Journal: Pan Afr Med J