| Literature DB >> 33773079 |
Lynn Williams1, Karen Deakin1, Allyson Gallant2, Susan Rasmussen1, David Young3, Nicola Cogan1.
Abstract
BACKGROUND: Seasonal influenza vaccination is recommended for patients with chronic respiratory conditions, but uptake is suboptimal. We undertook a comprehensive mixed methods study in order to examine the barriers and enablers to influenza vaccination in patients with chronic respiratory conditions.Entities:
Keywords: complacency; influenza; mixed methods; trust; vaccine hesitancy
Mesh:
Substances:
Year: 2021 PMID: 33773079 PMCID: PMC8404050 DOI: 10.1111/irv.12856
Source DB: PubMed Journal: Influenza Other Respir Viruses ISSN: 1750-2640 Impact factor: 4.380
Sociodemographic and health variables for the survey sample
| Variable | N | % |
|---|---|---|
| Gender | ||
| Female | 273 | 63.6 |
| Male | 149 | 34.7 |
| Missing | 7 | |
| Education | ||
| High School | 115 | 27.1 |
| College | 134 | 31.5 |
| University | 109 | 25.6 |
| Postgraduate | 67 | 15.8 |
| Missing | 4 | |
| Deprivation | ||
| SIMD 1 (most deprived) | 104 | 26.7 |
| SIMD 2 | 79 | 20.3 |
| SIMD 3 | 81 | 20.8 |
| SIMD 4 | 68 | 17.4 |
| SIMD 5 (least deprived) | 58 | 14.9 |
| Missing | 39 | |
| Type of respiratory condition | ||
| Asthma | 346 | 80.7 |
| COPD | 82 | 19.1 |
| Other | 29 | 6.8 |
| Severity of condition | ||
| Mild | 170 | 40.1 |
| Moderate | 208 | 49.1 |
| Severe | 46 | 10.8 |
| Missing | 5 | |
| Influenza vaccination uptake | ||
| Yes | 240 | 55.9 |
| No | 189 | 44.1 |
Integration of the main findings across the quantitative and qualitative studies
| Quantitative study | Qualitative study | Integration and synthesis |
|---|---|---|
| Older participants were more likely to get vaccinated | The quantitative findings suggest particular targeted efforts may be needed for younger adults with chronic respiratory conditions | |
| Having greater confidence in vaccines was associated with getting vaccinated (univariate analysis) | The perception that the vaccine causes adverse side effects as well as a lack of trust and rapport in general with HCPs was identified as a barrier | The importance of having trust in vaccines and the system that delivers them was identified in both components. Addressing concerns about side effects through transparent communication with healthcare providers may be important |
| Higher levels of complacency about vaccination were associated with not getting vaccinated | Acceptance of being at greater risk due to respiratory condition and the belief that influenza represented a significant threat to health’ leading to feelings of being protected, was a facilitator to vaccination | Both components identified the key role for an individual's perception of risk. Those who perceived influenza to be a significant threat and that they were at greater risk for it were more likely to get vaccinated |
| Higher perceptions of constraints around vaccination were associated with not getting vaccinated | Lack of knowledge about the vaccine was identified as a barrier, with participants wanting more detailed information tailored to their condition | Practical constraints were identified as being important in both components. The provision of more tailored information may be useful |
| Higher levels of collective responsibility were associated with getting vaccinated | Participants mentioned the importance of protecting vulnerable people that they were in contact with | The willingness to protect others was identified in both components. Emphasising that getting vaccinated can protect others, including vulnerable friends and family, may be useful |
Univariate analysis of influenza vaccination uptake
| Variable | Comparison | Coefficient | ||
|---|---|---|---|---|
| Age | .007 | – | 1.02 | – |
| Gender | .510 | Male vs female | 0.694 | – |
| Education | .080 | College vs high school | 1.25 | – |
| University vs high school | 1.20 | – | ||
| Postgraduate vs high school | 2.31 | – | ||
| Deprivation | .727 | SIMD 2 vs SIMD 1 (most deprived) | 1.00 | |
| SIMD 3 vs SIMD 1 (most deprived) | 1.16 | |||
| SIMD 4 vs SIMD 1 (most deprived) | 1.50 | |||
| SIMD 5 (least deprived) vs SIMD 1 (most deprived) | 1.22 | |||
| Severity of condition | .037 | Moderate vs mild | 0.44 | .020 |
| Severe vs mild | 0.32 | .192 | ||
| Confidence | <.001 | – | 1.59 | – |
| Complacency | <.001 | – | 0.501 | – |
| Constraints | <.001 | – | 0.507 | – |
| Calculation | .338 | – | 0.945 | – |
| Collective responsibility | <.001 | – | 2.05 | – |
Multivariate analysis of influenza vaccination uptake
| Variable | Comparison | Coefficient | |
|---|---|---|---|
| Age | .030 | – | 1.02 |
| Severity of condition | .118 | Moderate vs mild | 1.395 |
| Severe vs mild | 2.42 | ||
| Confidence | .060 | – | 1.19 |
| Complacency | .008 | – | 0.72 |
| Constraints | <.001 | – | 0.62 |
| Collective responsibility | .001 | – | 1.52 |