Silvana Pereira Giozza1, Ximena Pamela Díaz Bermúdez2, Edna Oliveira Kara3, Guilherme Amaral Calvet4, Ana Maria Bispo de Filippis5, Marcus Vinícius Guimarães Lacerda6,7, Camila Helena Aguiar Bôtto-Menezes8, Marcia da Costa Castilho7, Rafael Freitas Oliveira Franca9, Armando Menezes Neto9, Casey Storme10, Noemia S Lima10, Kayvon Modjarrad11, Maria Cristina Pimenta de Oliveira12, Gerson Fernando Mendes Pereira12, Nathalie Broutet3. 1. Department of Chronic Condition Diseases and Sexually Transmitted Infections, Health Surveillance Secretariat, Ministry of Health, Brazil, SRTVN Quadra 701, Lote D, Edifício PO700 - 5° andar, Brasília, Distrito Federal, 70719-040, Brazil. silvana.giozza@aids.gov.br. 2. Public Health Department, University of Brasilia, Brasilia, Brazil. 3. World Health Organization, Geneva, Switzerland. 4. Evandro Chagas National Institute of Infectious Diseases, Rio de Janeiro, Brazil. 5. Oswaldo Cruz Institute, Rio de Janeiro, Brazil. 6. Instituto Leônidas & Maria Deane, Fiocruz, Manaus, Brazil. 7. Tropical Medicine Foundation Dr Heitor Vieira Dourado, Manaus, Brazil. 8. Amazonas State University, Manaus, Brazil. 9. Oswaldo Cruz Foundation - Institute Aggeu Magalhães, Recife, Brazil. 10. Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA. 11. Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA. 12. Department of Chronic Condition Diseases and Sexually Transmitted Infections, Health Surveillance Secretariat, Ministry of Health, Brazil, SRTVN Quadra 701, Lote D, Edifício PO700 - 5° andar, Brasília, Distrito Federal, 70719-040, Brazil.
Abstract
BACKGROUND: The Zika virus outbreak has triggered a set of local and global actions for a rapid, effective, and timely public health response. A World Health Organization (WHO) initiative, supported by the Department of Chronic Condition Diseases and Sexually Transmitted Infections (DCCI) of the Health Surveillance Secretariat (SVS), Brazil Ministry of Health (MoH) and other public health funders, resulted in the start of the "Study on the persistence of Zika virus in body fluids of patients with ZIKV infection in Brazil - ZIKABRA study". The ZIKABRA study was designed to increase understanding of how long ZIKV persists in bodily fluids and informing best measures to prevent its transmission. Data collection began in July 2017 and the last follow up visit occurred in 06/26/2020. METHODS: A framework for the ZIKABRA Cooperation initiative is provided through a description and analysis of the mechanisms, strategies and the ethos that have guided the models of international governance and technical cooperation in health for scientific exchange in the context of a public health emergency. Among the methodological strategies, we included a review of the legal documents that supported the ZIKABRA Cooperation; weekly documents produced in the meetings and working sessions; technical reports; memorandum of understanding and the research protocol. CONCLUSION: We highlight the importance of working in cooperation between different institutional actors to achieve more significant results than that obtained by each group working in isolation. In addition, we point out the advantages of training activities, ongoing supervision, the construction of local installed research capacity, training academic and non-academic human resources, improvement of laboratory equipment, knowledge transfer and the availability of the ZIKABRA study protocol for development of similar studies, favoring the collective construction of knowledge to provide public health emergency responses. Strategy harmonization; human resources and health services; timing and recruiting particularities and processing institutional clearance in the different sites can be mentioned as challenges in this type of initiative.
BACKGROUND: The Zika virus outbreak has triggered a set of local and global actions for a rapid, effective, and timely public health response. A World Health Organization (WHO) initiative, supported by the Department of Chronic Condition Diseases and Sexually Transmitted Infections (DCCI) of the Health Surveillance Secretariat (SVS), Brazil Ministry of Health (MoH) and other public health funders, resulted in the start of the "Study on the persistence of Zika virus in body fluids of patients with ZIKV infection in Brazil - ZIKABRA study". The ZIKABRA study was designed to increase understanding of how long ZIKV persists in bodily fluids and informing best measures to prevent its transmission. Data collection began in July 2017 and the last follow up visit occurred in 06/26/2020. METHODS: A framework for the ZIKABRA Cooperation initiative is provided through a description and analysis of the mechanisms, strategies and the ethos that have guided the models of international governance and technical cooperation in health for scientific exchange in the context of a public health emergency. Among the methodological strategies, we included a review of the legal documents that supported the ZIKABRA Cooperation; weekly documents produced in the meetings and working sessions; technical reports; memorandum of understanding and the research protocol. CONCLUSION: We highlight the importance of working in cooperation between different institutional actors to achieve more significant results than that obtained by each group working in isolation. In addition, we point out the advantages of training activities, ongoing supervision, the construction of local installed research capacity, training academic and non-academic human resources, improvement of laboratory equipment, knowledge transfer and the availability of the ZIKABRA study protocol for development of similar studies, favoring the collective construction of knowledge to provide public health emergency responses. Strategy harmonization; human resources and health services; timing and recruiting particularities and processing institutional clearance in the different sites can be mentioned as challenges in this type of initiative.
Entities:
Keywords:
International cooperation in health; Outbreak; Public health emergency; Zika virus
Authors: Beatriz Parra; Jairo Lizarazo; Jorge A Jiménez-Arango; Andrés F Zea-Vera; Guillermo González-Manrique; José Vargas; Jorge A Angarita; Gonzalo Zuñiga; Reydmar Lopez-Gonzalez; Cindy L Beltran; Karen H Rizcala; Maria T Morales; Oscar Pacheco; Martha L Ospina; Anupama Kumar; David R Cornblath; Laura S Muñoz; Lyda Osorio; Paula Barreras; Carlos A Pardo Journal: N Engl J Med Date: 2016-10-05 Impact factor: 91.245
Authors: Kristina M Angelo; Rhett J Stoney; Gaelle Brun-Cottan; Karin Leder; Martin P Grobusch; Natasha Hochberg; Susan Kuhn; Emmanuel Bottieau; Patricia Schlagenhauf; Lin Chen; Noreen A Hynes; Cecilia Perret Perez; Frank P Mockenhaupt; Israel Molina; Clara Crespillo-Andújar; Denis Malvy; Eric Caumes; Pierre Plourde; Marc Shaw; Anne E McCarthy; Nancy Piper-Jenks; Bradley A Connor; Davidson H Hamer; Annelies Wilder-Smith Journal: J Travel Med Date: 2020-07-14 Impact factor: 8.490
Authors: Gibrilla F Deen; Nathalie Broutet; Wenbo Xu; Barbara Knust; Foday R Sesay; Suzanna L R McDonald; Elizabeth Ervin; Jaclyn E Marrinan; Philippe Gaillard; Ndema Habib; Hongtu Liu; William Liu; Anna E Thorson; Francis Yamba; Thomas A Massaquoi; Faustin James; Archchun Ariyarajah; Christine Ross; Kyle Bernstein; Antoine Coursier; John Klena; Marylin Carino; Alie H Wurie; Yong Zhang; Marion S Dumbuya; Neetu Abad; Baimba Idriss; Teodora Wi; Sarah D Bennett; Tina Davies; Faiqa K Ebrahim; Elissa Meites; Dhamari Naidoo; Samuel J Smith; Patricia Ongpin; Tasneem Malik; Anshu Banerjee; Bobbie R Erickson; Yongjian Liu; Yang Liu; Ke Xu; Aaron Brault; Kara N Durski; Jörn Winter; Tara Sealy; Stuart T Nichol; Margaret Lamunu; James Bangura; Sihem Landoulsi; Amara Jambai; Oliver Morgan; Guizhen Wu; Mifang Liang; Qiudong Su; Yu Lan; Yanzhe Hao; Pierre Formenty; Ute Ströher; Foday Sahr Journal: N Engl J Med Date: 2015-10-14 Impact factor: 91.245
Authors: Annelies Wilder-Smith; Yinghui Wei; Thalia Velho Barreto de Araújo; Maria VanKerkhove; Celina Maria Turchi Martelli; Marília Dalva Turchi; Mauro Teixeira; Adriana Tami; João Souza; Patricia Sousa; Antoni Soriano-Arandes; Carmen Soria-Segarra; Nuria Sanchez Clemente; Kerstin Daniela Rosenberger; Ludovic Reveiz; Arnaldo Prata-Barbosa; Léo Pomar; Luiza Emylce Pelá Rosado; Freddy Perez; Saulo D Passos; Mauricio Nogueira; Trevor P Noel; Antônio Moura da Silva; Maria Elisabeth Moreira; Ivonne Morales; Maria Consuelo Miranda Montoya; Demócrito de Barros Miranda-Filho; Lauren Maxwell; Calum N L Macpherson; Nicola Low; Zhiyi Lan; Angelle Desiree LaBeaud; Marion Koopmans; Caron Kim; Esaú João; Thomas Jaenisch; Cristina Barroso Hofer; Paul Gustafson; Patrick Gérardin; Jucelia S Ganz; Ana Carolina Fialho Dias; Vanessa Elias; Geraldo Duarte; Thomas Paul Alfons Debray; María Luisa Cafferata; Pierre Buekens; Nathalie Broutet; Elizabeth B Brickley; Patrícia Brasil; Fátima Brant; Sarah Bethencourt; Andrea Benedetti; Vivian Lida Avelino-Silva; Ricardo Arraes de Alencar Ximenes; Antonio Alves da Cunha; Jackeline Alger Journal: BMJ Open Date: 2019-06-18 Impact factor: 2.692
Authors: Camila Helena Aguiar Bôtto-Menezes; Armando Menezes Neto; Guilherme Amaral Calvet; Edna Oliveira Kara; Marcus Vinícius Guimarães Lacerda; Marcia da Costa Castilho; Ute Ströher; Carlos Alexandre Antunes de Brito; Kayvon Modjarrad; Nathalie Broutet; Patrícia Brasil; Ana Maria Bispo de Filippis; Rafael Freitas Oliveira Franca Journal: Emerg Infect Dis Date: 2019-05 Impact factor: 6.883
Authors: Nathan D Grubaugh; Sharada Saraf; Karthik Gangavarapu; Alexander Watts; Amanda L Tan; Rachel J Oidtman; Jason T Ladner; Glenn Oliveira; Nathaniel L Matteson; Moritz U G Kraemer; Chantal B F Vogels; Aaron Hentoff; Deepit Bhatia; Danielle Stanek; Blake Scott; Vanessa Landis; Ian Stryker; Marshall R Cone; Edgar W Kopp; Andrew C Cannons; Lea Heberlein-Larson; Stephen White; Leah D Gillis; Michael J Ricciardi; Jaclyn Kwal; Paola K Lichtenberger; Diogo M Magnani; David I Watkins; Gustavo Palacios; Davidson H Hamer; Lauren M Gardner; T Alex Perkins; Guy Baele; Kamran Khan; Andrea Morrison; Sharon Isern; Scott F Michael; Kristian G Andersen Journal: Cell Date: 2019-08-22 Impact factor: 41.582
Authors: Annelies Wilder-Smith; Raman Preet; Elizabeth B Brickley; Ricardo Arraes de Alencar Ximenes; Demócrito de Barros Miranda-Filho; Celina Maria Turchi Martelli; Thália Velho Barreto de Araújo; Ulisses Ramos Montarroyos; Maria Elisabeth Moreira; Marília Dalva Turchi; Tom Solomon; Bart C Jacobs; Carlos Pardo Villamizar; Lyda Osorio; Ana Maria Bispo de Filipps; Johan Neyts; Suzanne Kaptein; Ralph Huits; Kevin K Ariën; Hugh J Willison; Julia M Edgar; Susan C Barnett; Rosanna Peeling; Debi Boeras; Maria G Guzman; Aravinda M de Silva; Andrew K Falconar; Claudia Romero-Vivas; Michael W Gaunt; Alessandro Sette; Daniela Weiskopf; Louis Lambrechts; Helen Dolk; Joan K Morris; Ieda M Orioli; Kathleen M O'Reilly; Laith Yakob; Joacim Rocklöv; Cristiane Soares; Maria Lúcia Brito Ferreira; Rafael Freitas de Oliveira Franca; Alexander R Precioso; James Logan; Trudie Lang; Nina Jamieson; Eduardo Massad Journal: Glob Health Action Date: 2019 Impact factor: 2.640