Literature DB >> 33728133

Chronic Undiagnosed Brucellosis Presenting as Sciatica.

Meletis Rozis1, John Vlamis1, Spyros G Pneumaticos1.   

Abstract

Brucellosis is a common zoonotic disease in southern Europe. Although having the potential to harm several anatomic regions and systems, musculoskeletal manifestations are rare, usually involving the spine and the sacroiliac joints. In the literature, the reports of hip manifestations are sporadic. We present a case report of chronic, undiagnosed brucellosis indirectly affecting the hip joint. A 51-years-old male patient was admitted to our department with acute onset sciatica. His medical history was remarkable for incomplete cauda equina syndrome of unknown etiology and concomitant dura mater disruption, creating local sinuses resulting at the right buttock. On radiological evaluation, we demonstrated multiple abscesses of the lower lumbar spine and the ipsilateral sacroiliac joint, along with sinuses communicating with the right hip joint capsule. Soft and osseous tissue cultures obtained from the area of the lesion were negative for common bacteria. Considering the patient's history, chronicity of the disease, and the lesional pattern, we suspected brucellosis as a possible etiological factor. Laboratory evaluation with the serum agglutination test confirmed the diagnosis. The patient denied the surgical treatment, so we proceeded with chronic suppression antibiotics schemes. On 12-month follow-up, the patient has no clinical signs of infection relapse; he has reasonable pain control and a normal gait. Indirect hip infection due to chronic brucellosis is rare, and physicians should be very suspicious of the disease's characteristic radiological manifestations to reach a correct diagnosis.
Copyright © 2021, Rozis et al.

Entities:  

Keywords:  abscess; brucellosis; osteomyelitis; sinus

Year:  2021        PMID: 33728133      PMCID: PMC7936015          DOI: 10.7759/cureus.13114

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  20 in total

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Authors:  Nizar A Al-Nakshabandi
Journal:  Can Assoc Radiol J       Date:  2010-11-12       Impact factor: 2.248

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Journal:  J Clin Pharm Ther       Date:  2015-05-26       Impact factor: 2.512

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6.  Magnetic resonance imaging findings of musculoskeletal brucellosis.

Authors:  Zulkif Bozgeyik; Serpil Aglamis; Pinar Gundogan Bozdag; Affan Denk
Journal:  Clin Imaging       Date:  2014-04-21       Impact factor: 1.605

7.  Effect of hydroxychloroquine on treatment and recurrence of acute brucellosis: a single-blind, randomized clinical trial.

Authors:  Mohammad Mahdi Majzoobi; Seyyed Hamid Hashemi; Mojgan Mamani; Fariba Keramat; Jalal Poorolajal; Hamid Reza Ghasemi Basir
Journal:  Int J Antimicrob Agents       Date:  2017-08-04       Impact factor: 5.283

8.  Musculoskeletal involvement of brucellosis in different age groups: a study of 195 cases.

Authors:  Mehmet Faruk Geyik; Ali Gür; Kemal Nas; Remzi Cevik; Jale Saraç; Bunyamin Dikici; Celal Ayaz
Journal:  Swiss Med Wkly       Date:  2002-02-23       Impact factor: 2.193

9.  Doxycycline-rifampin versus doxycycline-streptomycin in treatment of human brucellosis due to Brucella melitensis. The GECMEI Group. Grupo de Estudio de Castilla-la Mancha de Enfermedades Infecciosas.

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Journal:  Antimicrob Agents Chemother       Date:  1995-09       Impact factor: 5.191

Review 10.  A Systematic Review and Meta-Analysis of Epidemiology and Clinical Manifestations of Human Brucellosis in China.

Authors:  Rongjiong Zheng; Songsong Xie; Xiaobo Lu; Lihua Sun; Yan Zhou; Yuexin Zhang; Kai Wang
Journal:  Biomed Res Int       Date:  2018-04-22       Impact factor: 3.411

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