Literature DB >> 33665072

Advanced platelet-rich fibrin plus and osseous bone graft for socket preservation and ridge augmentation - A randomized control clinical trial.

Manasi Yewale1, Subraya Bhat1,2, Abhay Kamath3, Aditi Tamrakar4, Vathsala Patil4, Adel S Algal2.   

Abstract

OBJECTIVE: To compare the clinical and radiographic effectiveness of A PRF Plus as an adjuctive material to osseous bone graft in socket preservation and ridge augmentation.
METHODS: Twenty patients with need to preserve extraction socket in non-molar sites planning for further prosthetic rehabilitation were divided into two groups. Test Group (Group A) was treated with A PRF Plus membrane and Sybograf plus ™ (70% HA and 30 %β TCP) bone graft. The Control Group (Group B) was treated with Sybograf plus ™ (70% HA and 30% βTCP) bone graft. Both groups had same socket preservation surgical technique.
RESULTS: Both Group A and Group B showed significant improvement in clinical and radiographic parameters. Mean socket length, Vertical Resorption reduction in Group A was 1.48 whereas in Group B was 1.67 which is statistically significant. (p ​≤ ​0.05). Changes in Horizontal width reduction at 1,3, and 5 ​mm depth of the socket for both groups were not statistically significant. The Gain in socket fill for Group A and B 6 months postoperatively was 1185.30HU ± 473.21 and 966.60 HU ± 273.27 respectively. But intergroup comparison was not statistically significant. (p ​= ​0.17). There were no significant statistical differences in postoperative pain in Group A and Group B as subjects experienced moderate amount of pain. The assessment of post-operative swelling showed that only 30% subjects in Group A reported with swelling. Whereas 80% subjects in Group B complained of post-operative swelling.
CONCLUSION: The results of the present study proved utilisation of A PRF Plus as a promising adjunct to conventional regenerative therapy for socket preservation.
© 2021 Craniofacial Research Foundation. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  A PRF Plus; Esthetics; Extraction socket; Implant; Osseous bone graft; Ridge preservation; Socket preservation

Year:  2021        PMID: 33665072      PMCID: PMC7900600          DOI: 10.1016/j.jobcr.2021.01.016

Source DB:  PubMed          Journal:  J Oral Biol Craniofac Res        ISSN: 2212-4268


  26 in total

Review 1.  Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF).

Authors:  David M Dohan Ehrenfest; Lars Rasmusson; Tomas Albrektsson
Journal:  Trends Biotechnol       Date:  2009-01-31       Impact factor: 19.536

Review 2.  Alveolar bone dimensional changes of post-extraction sockets in humans: a systematic review.

Authors:  Fridus Van der Weijden; Federico Dell'Acqua; Dagmar Else Slot
Journal:  J Clin Periodontol       Date:  2009-12       Impact factor: 8.728

Review 3.  Clinical and histologic outcomes of socket grafting after flapless tooth extraction: a systematic review of randomized controlled clinical trials.

Authors:  Shantanu Jambhekar; Florian Kernen; Avinash S Bidra
Journal:  J Prosthet Dent       Date:  2015-03-04       Impact factor: 3.426

4.  The use of leucocyte and platelet-rich fibrin in socket management and ridge preservation: a split-mouth, randomized, controlled clinical trial.

Authors:  Andy Temmerman; Jeroen Vandessel; Ana Castro; Reinhilde Jacobs; Wim Teughels; Nelson Pinto; Marc Quirynen
Journal:  J Clin Periodontol       Date:  2016-09-21       Impact factor: 8.728

5.  Optimized Platelet-Rich Fibrin With the Low-Speed Concept: Growth Factor Release, Biocompatibility, and Cellular Response.

Authors:  Masako Fujioka-Kobayashi; Richard J Miron; Maria Hernandez; Umadevi Kandalam; Yufeng Zhang; Joseph Choukroun
Journal:  J Periodontol       Date:  2016-09-02       Impact factor: 6.993

6.  Clinical evaluation alveolar ridge preservation with a beta-tricalcium phosphate socket graft.

Authors:  Robert A Horowitz; Ziv Mazor; Robert J Miller; Jack Krauser; Hari S Prasad; Michael D Rohrer
Journal:  Compend Contin Educ Dent       Date:  2009 Nov-Dec

7.  Effect of age and radiation on bone healing adjacent to hydroxyapatite placed in the tibia of rats.

Authors:  T Shirota; K Donath; K Ohno; Y Matsui; K Michi
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  1995-03

8.  Socket preservation by beta-tri-calcium phosphate with collagen compared to platelet-rich fibrin: A clinico-radiographic study.

Authors:  Swati Das; Rajesh Jhingran; Vivek Kumar Bains; Rohit Madan; Ruchi Srivastava; Iram Rizvi
Journal:  Eur J Dent       Date:  2016 Apr-Jun

Review 9.  Extraction Socket Preservation with or without Membranes, Soft Tissue Influence on Post Extraction Alveolar Ridge Preservation: a Systematic Review.

Authors:  Ricardo Faria-Almeida; Inesa Astramskaite-Januseviciene; Algirdas Puisys; Francisco Correia
Journal:  J Oral Maxillofac Res       Date:  2019-09-05

Review 10.  Platelet-rich Fibrin: A Paradigm in Periodontal Therapy - A Systematic Review.

Authors:  Umesh Pratap Verma; Rakesh Kumar Yadav; Manisha Dixit; Abhaya Gupta
Journal:  J Int Soc Prev Community Dent       Date:  2017-09-18
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  4 in total

1.  Clinical and radiographic evaluation of low-speed platelet-rich fibrin (PRF) for the treatment of intra-osseous defects of stage-III periodontitis patients: a randomized controlled clinical trial.

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Journal:  Clin Oral Investig       Date:  2022-07-25       Impact factor: 3.606

Review 2.  Efficacy of platelet-rich fibrin in promoting the healing of extraction sockets: a systematic review.

Authors:  Sarah Al-Maawi; Kathrin Becker; Frank Schwarz; Robert Sader; Shahram Ghanaati
Journal:  Int J Implant Dent       Date:  2021-12-19

Review 3.  Third-Generation Platelet Concentrates in Periodontal Regeneration: Gaining Ground in the Field of Regeneration.

Authors:  Unnati Shirbhate; Pavan Bajaj
Journal:  Cureus       Date:  2022-08-16

Review 4.  The Use of Biocompatible Membranes in Oral Surgery: The Past, Present & Future Directions. A Narrative Review.

Authors:  Ioannis Kormas; Alessandro Pedercini; Hatem Alassy; Larry F Wolff
Journal:  Membranes (Basel)       Date:  2022-08-29
  4 in total

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