Literature DB >> 27509214

The use of leucocyte and platelet-rich fibrin in socket management and ridge preservation: a split-mouth, randomized, controlled clinical trial.

Andy Temmerman1, Jeroen Vandessel2, Ana Castro3, Reinhilde Jacobs2, Wim Teughels3, Nelson Pinto4, Marc Quirynen3.   

Abstract

AIM: To investigate the influence of the use L-PRF as a socket filling material and its ridge preservation properties.
MATERIALS AND METHODS: Twenty-two patients in need of single bilateral and closely symmetrical tooth extractions in the maxilla or mandible were included in a split-mouth RCT. Treatments were randomly assigned (L-PRF socket filling versus natural healing). CBCT scans were obtained after tooth extraction and three months. Scans were evaluated by superimposition using the original DICOM data. Mean ridge width differences between timepoints were measured at three levels below the crest on both the buccal and lingual sides (crest -1 mm (primary outcome variable), -3 mm and -5 mm).
RESULTS: Mean vertical height changes at the buccal were -1.5 mm (±1.3) for control sites and 0.5 mm (±2.3) for test sites (p < 0.005). At the buccal side, control sites values were, respectively, -2.1 (±2.5), -0.3 mm (±0.3) (p < 0.005) and -0.1 mm (±0.0), and test sites values were, respectively, -0.6 mm (±2.2) (p < 0.005), -0.1 mm (±0.3) and 0.0 mm (±0.1). Significant differences (p < 0.005) were found for total width reduction between test (-22.84%) and control sites (-51.92%) at 1 mm below crest level. Significant differences were found for socket fill (visible mineralized bone) between test (94.7%) and control sites (63.3%).
CONCLUSION: The use of L-PRF as a socket filling material to achieve preservation of horizontal and vertical ridge dimension at three  months after tooth extraction is beneficial.
© 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  L-PRF; bone resorption; extraction socket; oral implant; platelet concentrates; ridge preservation

Mesh:

Year:  2016        PMID: 27509214     DOI: 10.1111/jcpe.12612

Source DB:  PubMed          Journal:  J Clin Periodontol        ISSN: 0303-6979            Impact factor:   8.728


  43 in total

Review 1.  The Role of Autologous Platelet Concentrates in Alveolar Socket Preservation: A Systematic Review.

Authors:  Marco Annunziata; Luigi Guida; Livia Nastri; Angelantonio Piccirillo; Linda Sommese; Claudio Napoli
Journal:  Transfus Med Hemother       Date:  2018-05-03       Impact factor: 3.747

2.  Advanced platelet-rich fibrin and freeze-dried bone allograft for ridge preservation: A randomized controlled clinical trial.

Authors:  Daniel Clark; Yogalakshmi Rajendran; Sarmad Paydar; Sunita Ho; Darren Cox; Mark Ryder; John Dollard; Richard T Kao
Journal:  J Periodontol       Date:  2018-04       Impact factor: 6.993

3.  Advanced platelet-rich-fibrin (A-PRF +) has no additional effect on the healing of post-extraction sockets of upper third molars. A split mouth randomized clinical trial.

Authors:  Davisson Alves Pereira; Pedro Gomes Junqueira Mendes; Nuryê Rezende Prisinoto; Gabriella Lopes de Rezende Barbosa; Priscilla Barbosa Ferreira Soares; Guilherme José Pimentel Lopes de Oliveira
Journal:  Oral Maxillofac Surg       Date:  2022-05-25

4.  The effect of dental pulp stem cells and L-PRF when placed into the extraction sockets of impacted mandibular third molars on the periodontal status of adjacent second molars: a split-mouth, randomized, controlled clinical trial.

Authors:  Seçil Cubuk; Bahar Fusun Oduncuoglu; Emine Elif Alaaddinoglu
Journal:  Oral Maxillofac Surg       Date:  2022-02-09

5.  Research progress of platelet-rich fibrin in alveolar ridge preservation.

Authors:  Shi-Lei Han; Hui-Guo Zhou; Na Li; Xiao-Hui Zhang; Hong-Hui Chen
Journal:  Rev Assoc Med Bras (1992)       Date:  2022-08       Impact factor: 1.712

6.  In Vitro and Ex Vivo Kinetic Release Profile of Growth Factors and Cytokines from Leucocyte- and Platelet-Rich Fibrin (L-PRF) Preparations.

Authors:  Xuzhu Wang; Melissa R Fok; George Pelekos; Lijian Jin; Maurizio S Tonetti
Journal:  Cells       Date:  2022-06-30       Impact factor: 7.666

Review 7.  Dimensional and histomorphometric evaluation of biomaterials used for alveolar ridge preservation: a systematic review and network meta-analysis.

Authors:  L Canullo; M Del Fabbro; S Khijmatgar; S Panda; A Ravidà; G Tommasato; A Sculean; P Pesce
Journal:  Clin Oral Investig       Date:  2021-11-26       Impact factor: 3.606

8.  Advanced platelet-rich fibrin plus and osseous bone graft for socket preservation and ridge augmentation - A randomized control clinical trial.

Authors:  Manasi Yewale; Subraya Bhat; Abhay Kamath; Aditi Tamrakar; Vathsala Patil; Adel S Algal
Journal:  J Oral Biol Craniofac Res       Date:  2021-02-03

9.  Impact of g force and timing on the characteristics of platelet-rich fibrin matrices.

Authors:  Ana B Castro; C Andrade; X Li; N Pinto; W Teughels; M Quirynen
Journal:  Sci Rep       Date:  2021-03-16       Impact factor: 4.379

10.  Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development.

Authors:  Momen A Atieh; Nabeel Hm Alsabeeha; Alan Gt Payne; Sara Ali; Clovis M Jr Faggion; Marco Esposito
Journal:  Cochrane Database Syst Rev       Date:  2021-04-26
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