Literature DB >> 33634220

Use of biologics in food allergy management.

Margitta Worm1, Wojciech Francuzik1, Sabine Dölle-Bierke1, Aikaterina Alexiou1.   

Abstract

Food allergies are a common medical problem, with children being the most affected patient group. The standard of care of food allergy consists of the acute treatment in case of a reaction and food avoidance in the long term, which influences the quality of life of patients. In this article, current developments for the causal treatment of food allergy including specific immunotherapy and biologics will be discussed. Epicutaneous and oral immunotherapy are currently in clinical development for the treatment of food allergy, and the results demonstrate good tolerability and efficacy with an increase in the oral threshold level. Biologics and, in particular, anti-IgE are currently investigated for their therapeutic use in food allergies. The results are promising, suggesting efficacy and tolerability. © Dustri-Verlag Dr. K. Feistle.

Entities:  

Keywords:  anti-IgE; efficacy; food allergy; oral tolerance induction

Year:  2021        PMID: 33634220      PMCID: PMC7901360          DOI: 10.5414/ALX02141E

Source DB:  PubMed          Journal:  Allergol Select        ISSN: 2512-8957


  23 in total

1.  First European data from the network of severe allergic reactions (NORA).

Authors:  M Worm; A Moneret-Vautrin; K Scherer; R Lang; M Fernandez-Rivas; V Cardona; M L Kowalski; M Jutel; I Poziomkowska-Gesicka; N G Papadopoulos; K Beyer; T Mustakov; G Christoff; M B Bilò; A Muraro; J O B Hourihane; L B Grabenhenrich
Journal:  Allergy       Date:  2014-08-16       Impact factor: 13.146

2.  Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis.

Authors:  Emma Guttman-Yassky; Robert Bissonnette; Benjamin Ungar; Mayte Suárez-Fariñas; Marius Ardeleanu; Hitokazu Esaki; Maria Suprun; Yeriel Estrada; Hui Xu; Xiangyu Peng; Jonathan I Silverberg; Alan Menter; James G Krueger; Rick Zhang; Usman Chaudhry; Brian Swanson; Neil M H Graham; Gianluca Pirozzi; George D Yancopoulos; Jennifer D D Hamilton
Journal:  J Allergy Clin Immunol       Date:  2018-09-05       Impact factor: 10.793

3.  Kinetics of mast cell, basophil, and oral food challenge responses in omalizumab-treated adults with peanut allergy.

Authors:  Jessica H Savage; Jean-Paul Courneya; Patricia M Sterba; Donald W Macglashan; Sarbjit S Saini; Robert A Wood
Journal:  J Allergy Clin Immunol       Date:  2012-07-15       Impact factor: 10.793

4.  Ligelizumab for Chronic Spontaneous Urticaria.

Authors:  Marcus Maurer; Ana M Giménez-Arnau; Gordon Sussman; Martin Metz; Diane R Baker; Andrea Bauer; Jonathan A Bernstein; Randolf Brehler; Chia-Yu Chu; Wen-Hung Chung; Inna Danilycheva; Clive Grattan; Jacques Hébert; Constance Katelaris; Michael Makris; Raisa Meshkova; Sinisa Savic; Rodney Sinclair; Karl Sitz; Petra Staubach; Bettina Wedi; Jürgen Löffler; Avantika Barve; Kenneth Kobayashi; Eva Hua; Thomas Severin; Reinhold Janocha
Journal:  N Engl J Med       Date:  2019-10-03       Impact factor: 91.245

5.  AR101 Oral Immunotherapy for Peanut Allergy.

Authors:  Brian P Vickery; Andrea Vereda; Thomas B Casale; Kirsten Beyer; George du Toit; Jonathan O Hourihane; Stacie M Jones; Wayne G Shreffler; Annette Marcantonio; Rezi Zawadzki; Lawrence Sher; Warner W Carr; Stanley Fineman; Leon Greos; Rima Rachid; M Dolores Ibáñez; Stephen Tilles; Amal H Assa’ad; Caroline Nilsson; Ned Rupp; Michael J Welch; Gordon Sussman; Sharon Chinthrajah; Katharina Blumchen; Ellen Sher; Jonathan M Spergel; Frederick E Leickly; Stefan Zielen; Julie Wang; Georgiana M Sanders; Robert A Wood; Amarjit Cheema; Carsten Bindslev-Jensen; Stephanie Leonard; Rita Kachru; Douglas T Johnston; Frank C Hampel; Edwin H Kim; Aikaterini Anagnostou; Jacqueline A Pongracic; Moshe Ben-Shoshan; Hemant P Sharma; Allan Stillerman; Hugh H Windom; William H Yang; Antonella Muraro; José M Zubeldia; Vibha Sharma; Morna J Dorsey; Hey J Chong; Jason Ohayon; J Andrew Bird; Tara F Carr; Dareen Siri; Montserrat Fernández-Rivas; David K Jeong; David M Fleischer; Jay A Lieberman; Anthony E J Dubois; Marina Tsoumani; Christina E Ciaccio; Jay M Portnoy; Lyndon E Mansfield; Stephen B Fritz; Bruce J Lanser; Jonathan Matz; Hanneke N G Oude Elberink; Pooja Varshney; Stephen G Dilly; Daniel C Adelman; A Wesley Burks
Journal:  N Engl J Med       Date:  2018-11-18       Impact factor: 91.245

6.  Efficacy and Safety of AR101 in Oral Immunotherapy for Peanut Allergy: Results of ARC001, a Randomized, Double-Blind, Placebo-Controlled Phase 2 Clinical Trial.

Authors:  J Andrew Bird; Jonathan M Spergel; Stacie M Jones; Rima Rachid; Amal H Assa'ad; Julie Wang; Stephanie A Leonard; Susan S Laubach; Edwin H Kim; Brian P Vickery; Benjamin P Davis; Jennifer Heimall; Antonella Cianferoni; Andrew J MacGinnitie; Elena Crestani; A Wesley Burks
Journal:  J Allergy Clin Immunol Pract       Date:  2017-10-31

7.  Effect of anti-IgE therapy in patients with peanut allergy.

Authors:  Donald Y M Leung; Hugh A Sampson; John W Yunginger; A Wesley Burks; Lynda C Schneider; Cornelis H Wortel; Frances M Davis; John D Hyun; William R Shanahan
Journal:  N Engl J Med       Date:  2003-03-10       Impact factor: 91.245

8.  Prevalence of adverse reactions to food in Germany - a population study.

Authors:  T Zuberbier; G Edenharter; M Worm; I Ehlers; S Reimann; T Hantke; C C Roehr; K E Bergmann; B Niggemann
Journal:  Allergy       Date:  2004-03       Impact factor: 13.146

Review 9.  Allergen immunotherapy for IgE-mediated food allergy: a systematic review and meta-analysis.

Authors:  U Nurmatov; S Dhami; S Arasi; G B Pajno; M Fernandez-Rivas; A Muraro; G Roberts; C Akdis; M Alvaro-Lozano; K Beyer; C Bindslev-Jensen; W Burks; G du Toit; M Ebisawa; P Eigenmann; E Knol; M Makela; K C Nadeau; L O'Mahony; N Papadopoulos; L K Poulsen; C Sackesen; H Sampson; A F Santos; R van Ree; F Timmermans; A Sheikh
Journal:  Allergy       Date:  2017-05-11       Impact factor: 13.146

Review 10.  Food allergy: immune mechanisms, diagnosis and immunotherapy.

Authors:  Wong Yu; Deborah M Hussey Freeland; Kari C Nadeau
Journal:  Nat Rev Immunol       Date:  2016-10-31       Impact factor: 53.106

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  1 in total

Review 1.  The Road Toward Transformative Treatments for Food Allergy.

Authors:  Allyssa Phelps; Kelly Bruton; Emily Grydziuszko; Joshua F E Koenig; Manel Jordana
Journal:  Front Allergy       Date:  2022-02-09
  1 in total

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