Literature DB >> 33580388

Taste Receptor Signaling.

Debarghya Dutta Banik1,2, Kathryn F Medler3.   

Abstract

All organisms have the ability to detect chemicals in the environment, which likely evolved out of organisms' needs to detect food sources and avoid potentially harmful compounds. The taste system detects chemicals and is used to determine whether potential food items will be ingested or rejected. The sense of taste detects five known taste qualities: bitter, sweet, salty, sour, and umami, which is the detection of amino acids, specifically glutamate. These different taste qualities encompass a wide variety of chemicals that differ in their structure and as a result, the peripheral taste utilizes numerous and diverse mechanisms to detect these stimuli. In this chapter, we will summarize what is currently known about the signaling mechanisms used by taste cells to transduce stimulus signals.
© 2021. The Author(s), under exclusive license to Springer Nature Switzerland AG.

Entities:  

Keywords:  Bitter; Peripheral taste cells; Salt; Signal transduction; Sour; Sweet; Umami

Mesh:

Year:  2022        PMID: 33580388     DOI: 10.1007/164_2021_442

Source DB:  PubMed          Journal:  Handb Exp Pharmacol        ISSN: 0171-2004


  140 in total

1.  Role of the G-protein subunit alpha-gustducin in taste cell responses to bitter stimuli.

Authors:  Alejandro Caicedo; Elizabeth Pereira; Robert F Margolskee; Stephen D Roper
Journal:  J Neurosci       Date:  2003-10-29       Impact factor: 6.167

2.  Nucleoside triphosphate diphosphohydrolase-2 is the ecto-ATPase of type I cells in taste buds.

Authors:  Dianna L Bartel; Susan L Sullivan; Elise G Lavoie; Jean Sévigny; Thomas E Finger
Journal:  J Comp Neurol       Date:  2006-07-01       Impact factor: 3.215

Review 3.  Genetics of taste receptors.

Authors:  Alexander A Bachmanov; Natalia P Bosak; Cailu Lin; Ichiro Matsumoto; Makoto Ohmoto; Danielle R Reed; Theodore M Nelson
Journal:  Curr Pharm Des       Date:  2014       Impact factor: 3.116

Review 4.  Vertebrate Bitter Taste Receptors: Keys for Survival in Changing Environments.

Authors:  Maik Behrens; Wolfgang Meyerhof
Journal:  J Agric Food Chem       Date:  2017-01-05       Impact factor: 5.279

5.  Individual mouse taste cells respond to multiple chemical stimuli.

Authors:  Alejandro Caicedo; Kyung-Nyun Kim; Stephen D Roper
Journal:  J Physiol       Date:  2002-10-15       Impact factor: 5.182

Review 6.  Sensory receptors of the larynx.

Authors:  R M Bradley
Journal:  Am J Med       Date:  2000-03-06       Impact factor: 4.965

7.  A novel family of mammalian taste receptors.

Authors:  E Adler; M A Hoon; K L Mueller; J Chandrashekar; N J Ryba; C S Zuker
Journal:  Cell       Date:  2000-03-17       Impact factor: 41.582

8.  T2Rs function as bitter taste receptors.

Authors:  J Chandrashekar; K L Mueller; M A Hoon; E Adler; L Feng; W Guo; C S Zuker; N J Ryba
Journal:  Cell       Date:  2000-03-17       Impact factor: 41.582

9.  Optogenetic Stimulation of Type I GAD65+ Cells in Taste Buds Activates Gustatory Neurons and Drives Appetitive Licking Behavior in Sodium-Depleted Mice.

Authors:  Caitlin Baumer-Harrison; Martin A Raymond; Thomas A Myers; Kolbe M Sussman; Spencer T Rynberg; Amanda P Ugartechea; Dean Lauterbach; Thomas G Mast; Joseph M Breza
Journal:  J Neurosci       Date:  2020-09-02       Impact factor: 6.167

10.  Amiloride-blockable sodium currents in isolated taste receptor cells.

Authors:  P Avenet; B Lindemann
Journal:  J Membr Biol       Date:  1988-11       Impact factor: 1.843

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