Literature DB >> 3355371

Effect of recombinant mouse interferon-beta on acute and latent herpes simplex infection in mice.

M Yamada1, Y Arao, A Hatano, F Uno, S Nii.   

Abstract

The antiviral effect of recombinant mouse interferon-beta (rMuIFN-beta) on herpes simplex virus type 1 (HSV-1) in experimentally infected mice was examined at several stages of infection as a model for the treatment of human HSV infection. Recombinant MuIFN-beta protected mice from lethal intraperitoneal challenge with virulent HSV-1 strains. The in vitro reactivation of HSV from latently infected trigeminal ganglia was also suppressed by treatment with rMuIFN-beta. Thus, rMuIFN-beta was effective against HSV-1 during acute infection and during in vitro reactivation of latent HSV. However, rMuIFN-beta was not effective in preventing the establishment of latent infection, or in eliminating a previously established latent infection.

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Year:  1988        PMID： 3355371     DOI： 10.1007/bf01311027

Source DB:  PubMed          Journal:  Arch Virol        ISSN： 0304-8608            Impact factor:   2.574


  23 in total

Review 1.  Structure of interferons.

Authors:  J A Langer; S Pestka
Journal:  Pharmacol Ther       Date:  1985       Impact factor: 12.310

2.  In vitro cytopathology and pathogenicity to inbred mice shown by five variants of a laboratory strain of type 1 herpes simplex virus.

Authors:  M Yamada; F Uno; S Nii
Journal:  Arch Virol       Date:  1986       Impact factor: 2.574

3.  Maintenance of latent herpetic infection: an apparent role for anti-viral IgG.

Authors:  J G Stevens; M L Cook
Journal:  J Immunol       Date:  1974-12       Impact factor: 5.422

4.  Spontaneous cytotoxicity mediated by human monocyte-macrophages against human fibroblasts infected with herpes simplex virsu--augmentation by interferon.

Authors:  T L Stanwick; D E Campbell; A J Nahmias
Journal:  Cell Immunol       Date:  1980-08-01       Impact factor: 4.868

5.  Giant cell-forming variants of the Miyama strain of type 1 herpes simplex virus which differ in fusion activity.

Authors:  S Nii; M Yamada; F Uno
Journal:  Biken J       Date:  1983-09

6.  Production of recombinant mouse beta-interferon.

Authors:  T Tanaka; M Naruto; G Kawano
Journal:  J Interferon Res       Date:  1986-08

7.  Latency of herpes simplex virus in absence of neutralizing antibody: model for reactivation.

Authors:  T Sekizawa; H Openshaw; C Wohlenberg; A L Notkins
Journal:  Science       Date:  1980-11-28       Impact factor: 47.728

8.  Inhibition by indomethacin of in vitro reactivation of latent herpes simplex virus type 1 in murine trigeminal ganglia.

Authors:  I Kurane; Y Tsuchiya; T Sekizawa; K Kumagai
Journal:  J Gen Virol       Date:  1984-10       Impact factor: 3.891

9.  Effects of oral treatment with acyclovir and bromovinyldeoxyuridine on the establishment of maintenance of latent herpes simplex virus infection in mice.

Authors:  H J Field; E De Clercq
Journal:  J Gen Virol       Date:  1981-10       Impact factor: 3.891

10.  Effect of acycloguanosine treatment of acute and latent herpes simplex infections in mice.

Authors:  H J Field; S E Bell; G B Elion; A A Nash; P Wildy
Journal:  Antimicrob Agents Chemother       Date:  1979-04       Impact factor: 5.191
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  4 in total

1.  The role of the immune system in establishment of herpes simplex virus latency--studies using CD4+ T-cell depleted mice.

Authors:  D S Schmidt; A M Eis-Hübinger; K E Schneweis
Journal:  Arch Virol       Date:  1993       Impact factor: 2.574

2.  Antiviral activity of limitin against encephalomyocarditis virus, herpes simplex virus, and mouse hepatitis virus: diverse requirements by limitin and alpha interferon for interferon regulatory factor 1.

Authors:  Shin-Ichiro Kawamoto; Kenji Oritani; Hideo Asada; Isao Takahashi; Jun Ishikawa; Hitoshi Yoshida; Masahide Yamada; Naoko Ishida; Hidetoshi Ujiie; Hiroaki Masaie; Yoshiaki Tomiyama; Yuji Matsuzawa
Journal:  J Virol       Date:  2003-09       Impact factor: 5.103

3.  Enhancement by TNF-alpha of reactivation and replication of latent herpes simplex virus from trigeminal ganglia of mice.

Authors:  I Walev; J Podlech; D Falke
Journal:  Arch Virol       Date:  1995       Impact factor: 2.574

4.  Alteration of intracerebral cytokine production in mice infected with herpes simplex virus types 1 and 2.

Authors:  G Lewandowski; M V Hobbs; F E Bloom
Journal:  J Neuroimmunol       Date:  1994-11       Impact factor: 3.478
  4 in total

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