Literature DB >> 8240008

The role of the immune system in establishment of herpes simplex virus latency--studies using CD4+ T-cell depleted mice.

D S Schmidt1, A M Eis-Hübinger, K E Schneweis.   

Abstract

The immunological mechanisms involved in establishment of herpes simplex virus (HSV) latency were studied in normal and CD4+ T-cell depleted C57BL/6J mice following intravaginal infection. During transition from acute to latent ganglionic infection two consecutive processes were observed: first, clearance of infectious virus from the ganglia, and second, reduction of the number of infected ganglia.

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Year:  1993        PMID： 8240008     DOI： 10.1007/bf01309753

Source DB:  PubMed          Journal:  Arch Virol        ISSN： 0304-8608            Impact factor:   2.574


  32 in total

1.  Viral persistence in neurons explained by lack of major histocompatibility class I expression.

Authors:  E Joly; L Mucke; M B Oldstone
Journal:  Science       Date:  1991-09-13       Impact factor: 47.728

2.  In vivo induction of H-2K/D antigens by recombinant interferon-gamma.

Authors:  F Momburg; N Koch; P Möller; G Moldenhauer; G J Hämmerling
Journal:  Eur J Immunol       Date:  1986-05       Impact factor: 5.532

3.  Effect of immune serum on the establishment of herpes simplex virus infection in trigeminal ganglia of hairless mice.

Authors:  R J Klein
Journal:  J Gen Virol       Date:  1980-08       Impact factor: 3.891

4.  Lyt-1+ T cells participate in recovery from ocular herpes simplex virus type 1 infection.

Authors:  J E Oakes; J T Rector; R N Lausch
Journal:  Invest Ophthalmol Vis Sci       Date:  1984-02       Impact factor: 4.799

5.  Effect of recombinant mouse interferon-beta on acute and latent herpes simplex infection in mice.

Authors:  M Yamada; Y Arao; A Hatano; F Uno; S Nii
Journal:  Arch Virol       Date:  1988       Impact factor: 2.574

6.  Effect of B cell suppression on primary infection and reinfection of mice with herpes simplex virus.

Authors:  A Simmons; A A Nash
Journal:  J Infect Dis       Date:  1987-04       Impact factor: 5.226

7.  Pathogenesis of genital herpes simplex virus infection in mice. IV. Quantitative aspects of viral latency.

Authors:  A M Eis; K E Schneweis
Journal:  Med Microbiol Immunol       Date:  1986       Impact factor: 3.402

8.  Passive immunization protects the mouse eye from damage after herpes simplex virus infection by limiting spread of virus in the nervous system.

Authors:  C Shimeld; T J Hill; W A Blyth; D L Easty
Journal:  J Gen Virol       Date:  1990-03       Impact factor: 3.891

9.  Pathogenesis of herpes simplex virus in B cell-suppressed mice: the relative roles of cell-mediated and humoral immunity.

Authors:  A K Kapoor; A A Nash; P Wildy
Journal:  J Gen Virol       Date:  1982-07       Impact factor: 3.891

10.  Differential expression and regulation of major histocompatibility complex (MHC) products in neural and glial cells of the human fetal brain.

Authors:  T Mauerhoff; R Pujol-Borrell; R Mirakian; G F Bottazzo
Journal:  J Neuroimmunol       Date:  1988-07       Impact factor: 3.478
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  3 in total

Review 1.  Aerosol therapy for the treatment of osteosarcoma lung metastases: targeting the Fas/FasL pathway and rationale for the use of gemcitabine.

Authors:  Nancy Gordon; Eugenie S Kleinerman
Journal:  J Aerosol Med Pulm Drug Deliv       Date:  2010-08       Impact factor: 2.849

2.  Correlation of virus replication, cytokine (TNF-alpha and IL-1) producing cells, neuronal necrosis and inflammation after intranasal infection of mice with herpes simplex virus strains of different virulence.

Authors:  I Walev; H P Dienes; J Bohl; J Podlech; D Falke
Journal:  Arch Virol       Date:  1995       Impact factor: 2.574

3.  Replication-defective virus vaccine-induced protection of mice from genital herpes simplex virus 2 requires CD4 T cells.

Authors:  Lynda A Morrison
Journal:  Virology       Date:  2008-04-14       Impact factor: 3.616
  3 in total

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